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Methylation issues like 80% of population. Methylation issues/folate that's now an added ingredient to every grain, cereal, pasta etc. detrimental to the body. MCAS = methylation pathways dysfunction.
Finally, watching my hives and inflammation dissolve every day until it all disappeared was definitely appeasing, I went with what I mentioned and after 20 days my urticaria disappeared. I just go'ogled the latest by Shane Zormander and now my skin is as smooth and healthy as it has ever been!
Sounds crazy but there is some truth because if you go off it I believe your symptoms will come right back from the beginning. Eczema rash and inflammation will return. If you are lucky it may not. What insurance company will cover you for life? I would think at some point they will start denying you because Dupixent is so expensive. And then what?
For some…. there is no stick, the mast cells are activating to benign substances. But if you are more in alignment with the research and work of Dr. Anne Maitland you will realize it’s becoming evident often there is an underlying unresolved condition that is keeping the mast cells over activated and in alert mode universally (responding to what seems benign triggers) and won’t stand down until the underlying condition is addressed or resolved. To always assume it’s a barking dog syndrome and there is no dog there… no stick hitting the piñata in your analogy… leaves the patient the person without the proper care and potential ability to address causation. Maybe entertain her recent up to date talk on the channel named Immune Deficiency Foundation. Her video is titled “Mast Cell Activation Disorder by Dr. Anne Maitland” for a more comprehensive breakdown. Thank you for shining a light on this.
Hello docs! I’d love to ask a question. My parents sometimes talk about a memory of me when I was very young. All of a sudden, they say my fingers and face got swollen like a balloon, and I was having difficulty breathing. Then, they gave me an allergy syrup, and the symptoms were gone. I’m not sure if this was anaphylaxy or something else. (They also say I loved eating bugs for real, ew, haha.) I don’t really have any kind of allergy now, no food, venom, or medicine as far as I realized. I don’t remember that experience since I was too little, but I am now 31 and have never experienced anything like that. I fear anaphylaxis, but I have never experienced any kind of mild, moderate, or severe reaction. I only sometimes have itchiness, and that’s all. Is something like that possible? Someone having anaphylaxis in childhood and never experienced any allergy or other anaphylaxis attacks in the future? Also, it’s strange they claim that they only gave me my syrup and everything was gone. A part of me thinks it could be just an allergic reaction and not anaphylaxis.
Hi - if you believe you have an allergy it is best to discuss this with an allergist or your primary care provider. Make sure to have a detailed history of when you feel that itchiness.
Thank u for focusing on this, but as someone with MCAS, I don’t necessarily agree with the definition given here as there are triggers for the symptoms (e.g. scents, food, plastic, changes in temperature, etc.). So while we have the same amount of mast cells, they just get activated in various systems by things that are usually benign
Thank you for sharing your experience. We have realized in making this series that MCDs are very complex and that everyone's experience is different. We have an episode all about triggers that may be interesting for you to listen to and maybe that will align more with your experience.
So glad that more people are talking about my community's illnesses!! Thank you. Many in my community love everyone who is working to raise awareness about our lives. And, thank you for being willing to take this bull by the horns. Simply raising awareness likely contributed to saving lives and improving our relationships with medical professionals. Whoohoo!! Thank you; thank you. A couple of constructive points that are borne out in the peer-reviewed literature and/or are generally accepted knowledge among mast cell patients and specialists. 1. Mast cells are triggered through other pathways than just the IgE pathway, which can lead to bizarre allergic-like/anaphylactic reactions to things that are not activating the IgE pathway. "Possible triggers of MCA are extensive, vary from patient to patient, and are not limited to immunoglobulin E-dependent allergies." (See text for Figure 1 in the article in Annals of Allergy, Asthma & Immunology linked below.) 2. Folks with MCAS do have triggers. The mast cells are not exploding for *no* reason most of the time, for most patients, in our community. I suspect that physicians sometimes have this perspective because they are not aware that mast cells can be triggered through routes other than the IgE pathway; so, they're not open to patients who tell them that they have triggers that the body does not make IgE for. pubmed.ncbi.nlm.nih.gov/26164792/ www.ncbi.nlm.nih.gov/pmc/articles/PMC8146469/ www.annallergy.org/article/S1081-1206(21)00494-4/fulltext The criticisms are only offered because so many members of our community experience medical gaslighting around their triggers because they are not triggers that the body makes IgE for (temperature variation, pressure changes, fragrances, vibration, etc.). And, some members of our community have died or otherwise been made seriously ill in medical settings -- because they were not believed with regard to their triggers. Thank you again!! *high five* Feel free to reach out to me, if you want to talk to a patient who's both a nerd and works to support other members of this illness community.
I taught i could never get rid of asthma,until i met Dr Obinyan on RU-vid,i recommended drugs from him,to my greatest surprise it worked perfectly 💯💚💚 .
I taught i could never get rid of asthma,until i met Dr Obinyan on RU-vid,i recommended drugs from him,to my greatest surprise it worked perfectly 💯💚💚 .
Yep, it's such a relief to see those nasty hives fade away day after day until they completely vanish, I went with what I pointed out not long ago and after 21 days the urticaria’s gone, I just go'ogled the latest by Shane Zormander and now my skin is as smooth and clean as ever!
