Our technologies are used by scientists and engineers in a wide range of industries and organizations to solve the challenges associated with maximizing productivity, developing better quality products and getting them to market faster. Our mission is to create superior solutions and services to deliver tangible economic impact through chemical, physical and structural analysis of materials.
Underpinned by extensive industry knowledge and expertise, our instruments help users better understand a wide variety of materials, from proteins and polymers to metals and building materials. Our technologies enable the measurement of parameters such as particle size, shape and zeta potential, biomolecular interactions and stability, rheological properties, elemental concentrations and crystallographic structure. The characterization of these properties is fundamental to predicting how a product will behave during use, to optimizing its performance and achieving manufacturing excellence.
Thanks for your comment. Ensuring cleanliness of the system is certainly one important factor to getting the best quality data. Fortunately, it is very easy to keep your Mastersizer system measurement ready due to the ease of access it offers for cleaning. With respect to the tubing used for wet dispersion, this can be swapped out for new tubing as frequently as you see fit. But you shouldn’t need to do this often. If you are testing samples where biofilm growth might be an issue, cleaning of the system with a suitable solvent could be an option, especially as the Mastersizer demonstrates very good chemical compatibility. And don’t forget we have exciting software features like Data Quality Guidance to warn you of factors which could be impacting your measurement data.
Hi @jomarcamu7057, yes the Eagon requires an extraction system to remove the fumes. You can either sit it under a extraction hood or connect it directly to an extraction system using supplied extraction pipes.
what is the difference in method parameters for 2000 and 3000 series. We have master sizer 2000 and we newly purchased Master sizer 3000. For that we need to develop our regular 2000 methods in 3000 model.
Thanks for your comment. It’s great to hear that you have recently purchased a Mastersizer 3000! When it comes to transferring methods from the Mastersizer 2000 to the Mastersizer 3000, we have a lot of content on our website to help you. We would recommend the following technical notes and webinar as staring points. Technical Note 1: www.malvernpanalytical.com/en/learn/knowledge-center/technical-notes/tn130912transferingmethodsmastersizer Technical Note 2: www.malvernpanalytical.com/en/learn/knowledge-center/technical-notes/tn130515transfermethodstoms3000 Webinar: www.malvernpanalytical.com/en/learn/events-and-training/webinars/w221115epims3000
Hi, do you mean Mastersizer? Mastersizer uses Laser Diffraction and the video you posted on is around Zetasizer, this uses Dynamic Light Scattering. Both techniques maybe useful in measuring CNT’s - dependent on their size range and agglomeration state. If you can clarify what system you have we can point you in the right direction.
@@MalvernPanalytical Hi, we have Master sizer with EV and MV unit. CNT size is 9.5nm. I have a CNT water dispersion 200ml. Please advise what shall me sample volume and which technique I must use. Many thanks
@@user-vf3mp5nn8l Your expected size of 9.5 nm is below the 10 nm lower limit of the Mastersizer (laser diffraction), but this is well within the capabilities of the Zetasizer (dynamic light scattering). However, aggregation of the CNTs will likely mean you measure sizes larger than 9.5 nm and so the Mastersizer should still be relevant. We cannot advise on volume of sample to be tested as we do not know the concentration etc. Best practice for Mastersizer dictates that you should aim for an obscuration of no more than 5%. As these are small particles, there is a high likelihood of multiple scattering at higher obscuration levels. Try measuring at different obscuration ranges and determine where you see stable sizes versus obscuration - it’s within this range that you should be testing.
If the lens and lines are cleaned, what else could be the most likely cause for a reading to fluctuate and not be within the specified obscuration range before the sample runs out? Thank you in advance..
Hi Andrea. Thanks for the question. Based on your comments, it sounds like you are running a dry analyses and observing a fluctuating obscuration reading during sample feeding. This could potentially be due to the feed rate not being optimised for your sample. You could look at investigating different feed rates to determine if you get a better response. If you are using the Aero S on Mastersizer 3000, the mesh basket and ball bearing aid could also help to pre-disperse any agglomerates in the hopper and smooth the flow in the hopper.
@@MalvernPanalytical Thank you for the response! Yes normally we would change the feed rate to experiment, we actually had it set pretty high-70% with the maximum hopper gap; but we were somewhat bound to following the exact procedure. I wound up decreasing the stabilization time from 0.5 to 0.1 or 0.2 secs before reading occurs and it worked great! 👍🏼
Thanks for your comment! We're thrilled you enjoyed the video! 😄 For citing RU-vid videos in your final thesis, consider following the guidelines provided by your academic institution or referencing style (like APA, MLA). Best of luck with your thesis! 📚✨
Matersizer analyser is based on mie theory. Mie theory compertable only with spherical particle, however mastersizer analyser analyse non spherical particle also. How it is possible and whats the accuracy of results??
Hi @santoshpatil4354, laser diffraction is ideally suited to spheres / spheroidal, or slightly irregular materials. It will handle most shapes however. Most particles will randomly move in relation to the laser, so we get a volume based response based on the orientation the particles present. You will get an equivalent sphere with the same volume as the particle. This however can lead to issues if there is any flow alignment occurring. This can often occur with very acicular materials, there it is possible to get 3 peaks, one from the width, one from the length and one in between based on those which are spinning and exposing all the dimensions
Thank you AliRaza for your inquiry. The Aero Funnel sample feeder allows for larger sample masses to be added to the Aero S and Aero M dispersion units without needing to open the dispersion unit lid. Measurements are quicker as a result, and the larger sample mass ensures users achieve good material sampling and more reproducible results. It is an excellent solution for coarse samples, such as coffee, or cohesive powders, such as calcium carbonate. For information, see our website: www.malvernpanalytical.com/en/products/product-range/mastersizer-range/mastersizer-3000/accessories/aero-funnel-sample-feeder
Thanks for your comments and we are pleased you liked the video. The diffusion coefficient is obtained from the relation Γ=D t q 2 where q is the scattering vector, given by q=(4πn/λ0)sin(θ/2). A fuller explanation can be found here - www.malvernpanalytical.com/en/learn/knowledge-center/technical-notes/tn101104dynamiclightscatteringintroduction
Why we do not obtain a zeta potential distribution peak charge measurement? Instead of having desired charge of sample & good quality results? Can you explain?
If enzymes are reusable, why would the ligand ever be saturated after the reaction equals equilibrium? Wouldn't the new product be relased and the previously-used enzymes would be available again?
Hi Tapas Pal, size is obtained from the correlation function by using various algorithms. There are two approaches that can be taken (1) cumulants determines the mean size (z-average diameter) and an estimate of the width of the distribution (polydispersity index) and is defined in ISO22412 (2018)) (2) a multiple exponential fit of the correlation function to obtain the distribution of particle sizes. There are various distribution algorithms available such as non-negative least squares (General Purpose or Multiple Narrow Modes or L-Curve). www.malvernpanalytical.com/en/learn/knowledge-center/faqs/FAQ160705CumulantsNNLS Hope this helps.
Thank you for your feedback! We appreciate your honesty and understand that the background music may not be to everyone's taste. We'll take your comment into consideration for future videos and do our best to strike a better balance between the music and the narration so that it enhances rather than detracts from the viewing experience.
Thanks for your question. We assume that you are referring to the Document Wavelength in the Document Settings dialog. If that is the case, be aware that this is editable only in case there is NO Scan loaded. In case measurement data is present, the Anode material is selected/edited in the Object Inspector per Scan/dataset.
Thank you for watching! The music was chosen to match the video's tone. We're sorry if it wasn't to your liking, but we hope it didn't affect your enjoyment. We're open to suggestions for future videos. Thanks again!
@@MalvernPanalytical It was a great informative video. The main issue was the music being a bit loud, so focussing on the voice explaining was a little difficult for me.
Hi Ashwin, thank you for your question. The Multicore optics only consists of the iCore (incident beam optics) and dCore (diffracted beam optics). Hope this answers your question.
Hi Ashwin, The MultiCore represents the incident beam optic iCore and the diffracted beam optic dCore. As of the detector, we have the choice between 1Der or PIXcel for the dCore. The detector is positioned behind the dCore optics as for the X-Ray tube, that is situated in front of the iCore. Hope this helps.
Hi Abhishek, to measure the PSD of chocolate you need to disperse it in some kind of oil. Many oils are used - Akomed R, Sunflower oil, Isopar G. A fresh production sample (semi molten) will disperse into the oil with a little shaking, a solid chocolate will probably need some ultrasound. This will result in a chocolate / oil mix which can be added to a Mastersizer wet tank circulating clean oil for measurement. For analysis optical properties the industry tends to use the Fraunhofer model which is an option in our software. Hope this helps.
Thank you Dasun for your question. There are several reasons you may get seeming different answers from different particle sizing techniques such as laser diffraction and sieving. Notably they will be measuring different properties of the particles. You can find out more by visiting our website, search on Mastersizer masterclass. Or feel free to contact your local representative www.malvernpanalytical.com/en/about-us/contact-us/
I have an script that with each analysis show the results on a excel sheet, but i also have a problem with that, this excel that the software is making by the scrip, has a file extension of .out, this is causing me problems in the way that access can’t read .out files. Is there a way to change the .out for .xlsx?
Hello, Thanks for your question. As is often the case it depends on the application and the sample! If you are running an automated measurement the 50x that will be used for the Ramana part of the analysis. In this case you select the objective most suited for the Morphological part of the analysis and the system will automatically switch to the 50x to acquire each spectrum. In our support materials there is guidance around which objective to select if you will be performing a full MDRS analysis depending on the particle size. If you are using the system in manual mode then it is possible to acquire a spectrum using other objectives, and which you choose will depend on the sample eg particle size and scattering efficiency. Please do reach out to your local Malvern Panalytical support for further guidance or training. I hope this helps you with your MDRS application.
@@MalvernPanalytical this info will helpful to us. We have separated particle which is very small in amount,we are getting spectra of backgroung not the single particle.any reason..
There are various reasons that may lead to you not getting a good spectrum from your particle. It may be related to the particle size and/or the scattering efficiency of the material. Some materials are not Raman active. The spot size of the Raman beam is ~2um. If the particles of interest are smaller than this and/or are weak scatters then you can try extending the acquisition time. You can also consider applying a background correction. The parameters to use can be very application and sample specific. Your local support team will be happy to advise how they can offer more guidance on your specific application. Find your local team here www.malvernpanalytical.com/en/about-us/contact-us
Thank you for your question Ruhul Amin, C-18 particles are likely hydrophobic and hence will probably need some aid in bringing into a suspension with the use of suitable surfactants or a move to an organic dispersion medium. I’m sorry but we can’t answer to any great depth here or without knowing more about the samples and purpose. We would advise you to contact you local MP technical centre for more application specific advice.
