This Channels hosts a series of Nephrology-themed blackboard videos that would be an excellent resource for medical students, Internal Medicine residents, Nephrology fellows or faculty or anyone curious about kidney diseases and kidney physiology.
I' skinny, so I try to improve. I lift weights every 2-3 days. I take protein powder at least 5 days per week. My Proteinuria is 144mg/l in 24h (double the normal leve?l). Is that ok, considering my regimen? or is it too high regardless the fact that I take protein supplements, and I'm ruining my kidneys? should I quit protein powder? I'm 43 years old (with 2 kidney stones; 4.5 and 7.4mm). I like the fact that you said the the value should be less than 150mg per day, but when I had done a google search most results say it should be less than 80 and even my medical report says reference minor than 80. So, I'm totally confused.
1:16 maybe the body really needs high PTH/hyperparathyroidism to compensate, just like it has been shown that increased fgf23 compensates for loss of phosphate filtration 4:16 why would phosphorus be high, when fgf23 specifically keeps phosphorus levels low? (unless you already interfered with fgf23). More calcium may be mobilized by the body to maintain Ph: it's actually super logical, reduced kidney function means reduced bicarbonate production. You guys messing with the wrong issues. Instead, patients should eat baking soda to compensate. It has already been shown that baking soda intake intake increases sports performance, so hardly can hurt. Actually there even is a study for this: "NaHCO3 supplementation produces a dose-dependent increase in serum bicarbonate and improves lower extremity muscle strength after a short-term intervention in CKD patients with mild acidosis."
1:43 that just boggles the mind now doesn't it. No test for erythropoietin to give erythropoietin, and no serum iron criteria (actual iron made available by the body) to give iron. Erythroferrone hormone would suppress hepcidin, ie if the body needs blood, it overrides inflammation concerns. So serum iron would still be a decent test, at least after erythropoietin levels were checked and corrected. 8:09 the mean Hb level for women is 12. So how can you be deficient just below that? Isn't the standard definition of anemia outside of nephrology two standard deviations from the mean? 9:25 Ferritin less than 100 is not only normal but healthy. You guys are insane, I'm sorry to say, to want to get ferritin above 500. I'm not sure I have words for this: 325 mg iron three times daily for 1-3 months? That's more than 30g of iron in one month. Give absorption of 15%, that's 4.5g - 13.5g extra iron that can't leave the body, ever, pretty much. Normal total body iron is 2g - 4g. I think erythropoietin can be prescribed by other doctors not bound by these guidelines.
In metabolic acidosis, the purported theory is - the high H ion concentration reduces the action of the Na/K ATPase leading to less K uptake by cells. This means K ions build up in the extracellular fluid compartment.