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Powerhouse of the Cell
Powerhouse of the Cell
Powerhouse of the Cell
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Powerhouse of the Cell (formerly Primo Science) aims to achieve two goals:

1) To teach science though animations: From my 5+ years of tutoring high school students, I found that it was often challenging to visualize biological and chemical processes through a textbook or blackboard. Powerhouse serves to create a visual resource for students and educators to use to facilitate learning and improve performance.

2) To teach science through experimentation: After doing research in college, my peers and I realized that it was challenging to translate the material learned from classes into the laboratory. While courses often focus on already-discovered processes and mechanisms, science in the real world (not just in the laboratory) requires creative thinking and critical analysis. Powerhouse teaches the stories of famous biological discoveries to help students expand their view of science.

Videos are created and animated by Harrison Ngue, student at Harvard University.
Комментарии
@zqxzqxzqx1
@zqxzqxzqx1 День назад
I'm just a housewife and grandma who's been fascinated by CRISPR Cas9 since the beginning. I even read Code Breaker. I'm so excited to now hear that this is being used to cure sickle cell, blindness, and deafness. Amazing.
@timrowland9422
@timrowland9422 2 дня назад
The Nobel Prize is no longer a distinction of honour and integrity.
@shashpalsidhu2420
@shashpalsidhu2420 3 дня назад
THANK YOU , YOU HAVE EXPLAINED THIES GENIUS CONCEPT IN A REALLY GOOD WAY. THANKS
@adamazmihan196
@adamazmihan196 3 дня назад
Beautiful, I love it. Thank you
@monishrules6580
@monishrules6580 3 дня назад
I wonder how it actually reads the instructions? Guess i might find it out in the next videos,thanks for making this! I love it!
@user-gs8jg7ym4o
@user-gs8jg7ym4o 8 дней назад
Hello, i want to ask you something, could CRISPR Technology be a solution for clinefertel syndrome (47 xxy)?
@khansaahabib219
@khansaahabib219 13 дней назад
Very well explained excellent❤
@EternalFootman-kr6yx
@EternalFootman-kr6yx 13 дней назад
This is science fiction. DNA and genes do not exist. Like sten how glib and brainwashed this guy is
@greatguytv
@greatguytv 18 дней назад
24y5m WiFi is working well Considering.. Did you make this during the heat wave?
@gustavplauen2448
@gustavplauen2448 29 дней назад
Hey bro I don't know how to contact you so I will try it here. I have a VERY important presentation in school and its also about CRISPR-Cas9 so I had the question if you could send me the animations you did in this video so I can put them into my powerpoint? That would skyrocket my grade and help me a lot. is there a way I could dm you on instagram or something so we could figure a way out how you can send it to me? Thank you for your help.
@shotto11
@shotto11 Месяц назад
People don’t realize the amount of knowledge that was put into this video…
@PowerhouseCell
@PowerhouseCell Месяц назад
Thank you so much! I'm thrilled you appreciate the effort that went into it :)
@user-tw8vt7qz2w
@user-tw8vt7qz2w Месяц назад
wait so basically cas9 is like fanum and the DNA is kai and crispr is the fanum tax
@user-tw8vt7qz2w
@user-tw8vt7qz2w Месяц назад
on god
@user-tw8vt7qz2w
@user-tw8vt7qz2w Месяц назад
on fanum
@PowerhouseCell
@PowerhouseCell Месяц назад
based
@kevinarani9033
@kevinarani9033 Месяц назад
Awesome video man!
@PowerhouseCell
@PowerhouseCell Месяц назад
Thank you for watching and commenting!
@meartin
@meartin Месяц назад
Plz come back man the world needs you😢😮
@PowerhouseCell
@PowerhouseCell Месяц назад
Thank you so much for the love and support! More videos are definitely on the way - each video just takes upwards of 200 hours to finish so the process unfortunately takes longer than any of us would like haha
@meartin
@meartin Месяц назад
@@PowerhouseCell I understand 😅🙏
@PowerhouseCell
@PowerhouseCell Месяц назад
I appreciate the support nonetheless! :)
@kedarnavsariwala348
@kedarnavsariwala348 Месяц назад
Dammn that last sentence "maybe that scientist who will accomplish these feats in the future is watching this video right now." felt really emotional for some reason. Thanks
@PowerhouseCell
@PowerhouseCell Месяц назад
It could be true! Keep doing what you're doing :)
@Dr.Reason
@Dr.Reason Месяц назад
This “God mentality” from the generation that thinks making eunics of men somehow turns them into actual women. But a very good vide to describe what science is doing today.
@slendrmusic
@slendrmusic Месяц назад
nice
@PowerhouseCell
@PowerhouseCell Месяц назад
Glad you enjoyed!
@salenaj
@salenaj Месяц назад
love how you simplify topics, it is great video! Sad to see you've stopped making them, but thanks for all the awesome content. Good luck with everything you're doing now!
@PowerhouseCell
@PowerhouseCell Месяц назад
Hearing from viewers like you makes all the hard work worth it. And I haven't stopped permanently - each video just takes hundreds of hours to make, so I've been working on my most recent video for over a year now. Hope I can get it out within the next few months. More videos coming soon!
@anjac8131
@anjac8131 Месяц назад
Thank you so much. It finally makes sense 😊
@PowerhouseCell
@PowerhouseCell Месяц назад
I'm thrilled to hear that the video was helpful for you! If you have any more questions, feel free to ask :)
@IzumeePriya
@IzumeePriya Месяц назад
THANKYOU SO MUCH , YOUR VIDEOS REALLY HELP
@PowerhouseCell
@PowerhouseCell Месяц назад
Your comment made my day! I'm thrilled that the video was able to make things clearer for you.
@she.s.just.a.friend
@she.s.just.a.friend Месяц назад
This was such a useful video and explained things so well but I'm a bit confused as to when the ZFNs were developped because when hes speaking he says 1:20 it was developped in 1994 but on the actual screen it says 1:26 "1985: discovery of zinc finger nuceases". I would love it if someone could pls explain it to me.
@PowerhouseCell
@PowerhouseCell Месяц назад
Good catch! Zinc finger nucleases were _discovered_ in 1985, but they were first _used_ in the context of genome editing in 1994. It's kind of like how microwaves (the form of energy) were discovered in the 1800s, but they didn't invent the microwave oven until the 1940s.
@nonime9566
@nonime9566 2 месяца назад
It was a great video, but the music was a bit distracting. Maybe making it a bit more quiet could help?
@PowerhouseCell
@PowerhouseCell Месяц назад
Thanks for your feedback! I unfortunately cannot change the volume of the music on this already-uploaded video, but I'll keep that in mind for any future videos.
@archiewebster5034
@archiewebster5034 2 месяца назад
thanks for the clear imagery in the explination of Cirspr Cas9's structure, it helped a lot.
@PowerhouseCell
@PowerhouseCell Месяц назад
It's fantastic to hear that the video was helpful! Stay tuned for more exciting content
@bielborrellserra4365
@bielborrellserra4365 2 месяца назад
outstanding
@PowerhouseCell
@PowerhouseCell Месяц назад
Glad you enjoyed! Hope you were able to learn something new :)
@victorsaldiviacardoch8797
@victorsaldiviacardoch8797 2 месяца назад
please come back
@PowerhouseCell
@PowerhouseCell Месяц назад
Thank you so much for the love and support! More videos are definitely on the way - each video just takes upwards of 200 hours to finish so the process unfortunately takes longer than any of us would like haha. I've been working on my latest video for over a year now. Hope to get it out within the next few months!
@alexboianghu
@alexboianghu 3 месяца назад
Are there good beginner books on this topic?
@ImperialKnight86
@ImperialKnight86 2 месяца назад
Commenting so if someone replies, I'll know too.
@PowerhouseCell
@PowerhouseCell Месяц назад
Great question! I actually don't know of any beginner books about CRISPR-Cas9 itself (will update this comment if I find any), but "The Code Breaker" is a wonderful book that goes through the history of the discovery of gene editing technology and is relatively straightforward to understand. If you get the chance to read it, let me know what you think!
@aykcavusyan2001
@aykcavusyan2001 3 месяца назад
Amazing ❤
@PowerhouseCell
@PowerhouseCell Месяц назад
Thanks 😄
@ayenpatel3738
@ayenpatel3738 3 месяца назад
bro u making videos plz need a lot , i have 60K followers on insta ,its a physics page ,i will promote your videos there .plz dont stop making videos your teaching way is best .
@ayenpatel3738
@ayenpatel3738 3 месяца назад
best biology channel to explain what teachers explain in 2hrs class ,bro explained in 15 mins,am your new subscriber , i will surely promote your page on insta
@PowerhouseCell
@PowerhouseCell Месяц назад
Wow, your comment made my day! I'm delighted that my videos are helping you grasp biology concepts efficiently. Thank you for subscribing and sharing the love on Instagram!
@mytho_raj
@mytho_raj 3 месяца назад
Just subbed brilliant content. Keep it up Sir
@PowerhouseCell
@PowerhouseCell Месяц назад
Your comment put a smile on my face! I'm glad my videos are resonating with you and helping you learn biology more efficiently.
@ilaila3504
@ilaila3504 3 месяца назад
What? At 1.32I don't know what you're saying. Need subtitles for hearing loss people and deaf folk x
@PowerhouseCell
@PowerhouseCell 3 месяца назад
This video has subtitles! Go to the video settings to turn them on :)
@topyoutopia
@topyoutopia 3 месяца назад
Please Sir make moreeeeee
@PowerhouseCell
@PowerhouseCell Месяц назад
Will definitely make more! Each video takes hundreds of hours to make, and I've been working on my latest video for over a year now. Hope to get it out within the next few months, so stay tuned :)
@imho2278
@imho2278 3 месяца назад
Please remove the piano music. Its pattern causes distraction.
@PowerhouseCell
@PowerhouseCell Месяц назад
Thanks for your feedback! I unfortunately cannot change the volume of the music on this already-uploaded video, but I'll keep that in mind for any future videos.
@mohammedy.salemalihorbi1210
@mohammedy.salemalihorbi1210 3 месяца назад
Great explanation, Thanks!
@PowerhouseCell
@PowerhouseCell Месяц назад
Glad it was helpful!
@saisohamdani7487
@saisohamdani7487 3 месяца назад
What an explanation sir ,❤️
@PowerhouseCell
@PowerhouseCell Месяц назад
Thanks a ton! I'm glad these videos are making a difference for you :D
@clareannarao3094
@clareannarao3094 3 месяца назад
This is one of the best videos of CRISPR that I've watched!
@PowerhouseCell
@PowerhouseCell Месяц назад
Wow, thank you so much for the incredible feedback! Definitely feel free to share with friends and colleagues who might find this helpful.
@yijingwang7308
@yijingwang7308 3 месяца назад
Look forward to a tutorial on how to make this video
@rodrigohuallanca662
@rodrigohuallanca662 3 месяца назад
Best explanation found so far! good job.
@PowerhouseCell
@PowerhouseCell Месяц назад
Thanks for your kind words! It's fantastic to hear that my videos are helping you understand biology better. Definitely feel free to share with friends and colleagues who might find this helpful :)
@williamrbuchanan4153
@williamrbuchanan4153 3 месяца назад
Beginning to go into , interfering with natural processes. Not advisable. “ Gain of function” for power of humans for financial gain or weaponise our DNA as they require. Not ours to be messing with means , DNA is a random with many variables . Ability to go there is not advised. But once the ability has been spread, like Guns,. . Tool or weapon, or profit use likely to become abuse.
@wernerustettler9731
@wernerustettler9731 3 месяца назад
We have, say 28 billion cells esch with a complete set of DNA. CRISPR is the method to cut out deffective Gens in the DNA of one Cell and replace it with a new Gen. How will thereafter all 28 billion -1 update their DNA? I have no clou as the multitude of humans have. Will appreciate some factual insight. Thanks
@user-gi2kr8sn8d
@user-gi2kr8sn8d 3 месяца назад
LS1B enthusiast?
@PowerhouseCell
@PowerhouseCell Месяц назад
I took LS50!
@anirbanmaitra6051
@anirbanmaitra6051 4 месяца назад
So brilliant!
@PowerhouseCell
@PowerhouseCell Месяц назад
Glad you enjoyed! Thanks for the support ❤️
@nicoleminotti8429
@nicoleminotti8429 4 месяца назад
Most understandable and clear explanation of CRISPR. This makes me want to take Chem 177! And I had no idea David Liu's lab is doing this cutting edge research...amazing. CCB is so cut off from what the Medical School and Broad labs are doing. :(
@PowerhouseCell
@PowerhouseCell Месяц назад
Thanks for your kind words, this really means a lot to me. Yes, super exciting stuff is happening at the Broad and HMS, but that doesn't take away at all from the neat work happening in the Jacobsen group and the rest of CCB. Thanks for all you do :)
@RichardWilkin
@RichardWilkin 4 месяца назад
I do appreciate (14:40) this video. It’s really great communication. Thanks!
@PowerhouseCell
@PowerhouseCell Месяц назад
Your appreciation motivates me to keep creating content. Thank you for your support!
@kamilaalicja2744
@kamilaalicja2744 4 месяца назад
Thank you very much for such a clever video! Make more of them in the name of science!
@PowerhouseCell
@PowerhouseCell Месяц назад
I'm grateful for your kind words! I definitely am in the process of making more. Have been working on my latest video for over a year now; hope I can get it out soon!
@AvantikaExpresses
@AvantikaExpresses 4 месяца назад
amazing video. it's so easy to focus on the small details in bio and forget the big picture. this was so helpful.
@PowerhouseCell
@PowerhouseCell Месяц назад
My main goal with every video is to emphasize the big picture, since that so often seems to get lost in textbooks and lectures. I'm really happy to hear you enjoyed! Please feel free to share with anyone who might find these videos helpful.
@directioner578
@directioner578 4 месяца назад
what an awesome video, it was so smooth and you explained everything in such an easy way!!
@PowerhouseCell
@PowerhouseCell Месяц назад
Glad you liked it!! Feel free to share with any friends or colleagues who might also find this helpful :)
@ezzovonachalm9815
@ezzovonachalm9815 4 месяца назад
Tout ce qui se conçoit bien s'exprime clairement/ Et les mots pour le dire s ' empruntent à l'allemand ! 2 alexandrins de 12 pieds chacun. C' est l' abbé Gamboni, professeur d' allemand du petit séminaire St Louis de Gonzague, à Genève, la Rome du protestantisme, qui nous l'a enseigné ( en remplaçant [aisément] par [allemand]) Ces 2 strophes s'appliquent comme un gant à la présentation cy- dedans!
@v.prestorpnrcrtlcrt2096
@v.prestorpnrcrtlcrt2096 4 месяца назад
Why is the animation opposite of what you are saying? Re NGG pointing to AGG
@PowerhouseCell
@PowerhouseCell Месяц назад
These aren't opposites! "N" just means any nucleotide can be in that spot (A,T,C,G), so "NGG" can refer to AGG, TGG, CGG, or GGG.
@OkNowImWatching
@OkNowImWatching 4 месяца назад
Amazing video! Thank you for taking the time to get everything in order and drawn out clearly
@PowerhouseCell
@PowerhouseCell Месяц назад
You're very welcome! It takes a long time, but it's viewers like you who make it all worth it. Feel free to share with any friends or colleagues who might find this helpful!