Love this conversation. Lot's of excellent advice. Very important to consider agronomic needs AND economic abilities of your operation. Don't forget the low interest and no interest finance offers available to help balance that decision and put off paying until after harvest.
Spraying kills the essential soil microorganisms, lowers fertility. Do you focus on fertility, e.g., measuring it year to year? You do that and the fertility will grow/protect your crops. Also, NEVER leave the ground fallow, plant a cover crop.