This is really silly, but.... I played this when I was in 3rd grade, and I had the most massive crush on some girl in my class. For some reason, this song reminded me of her, and I used to teleport back to Winters just to wander around listening to this music and daydreaming about rescuing that girl from evil and going on adventures all over the world together, just like Ness and Paula. This song is a flashback to a very innocent time.
I love the Runaway Five. They give so much happy energy to the game, and their performances are great too. And don't forget they helped you beat the Clumsy Robot!