At first I thought "Geez, the boss puts on a Bond of Life that needs to be cleared and Arlecchino requires her BoL to dish out damage, this is not going to be fun." But putting the BoL onto other characters was actually a good strategy, since they can have it be cleared off.
actually, to evade horned skulls is better to be in floor 3, and right before the eyes have contact with you, you go down, because if you go up you may crush your head with another skull, while you already had the path down you