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Scripps Research is ranked the most influential institution in the world for its impact on innovation. We expand basic knowledge in the biosciences, and use these fundamental advancements to develop profound innovations that improve wellbeing. Our researchers lead breakthrough studies that address the world’s most pressing health concerns. Our educational and training programs mold talented and committed students and postdocs into the next generation of leading scientists. We are accelerating the creation and delivery of medical breakthroughs to better human health around the globe.

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Regenerating tissues to treat disease
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Front Row Spotlight: Jeff Kelly
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The John C. Martin Memorial Lectureship | 2024
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Bringing precision therapy to mental disorders
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Scripps Research Day Highlights
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Комментарии
@mashroom2927
@mashroom2927 Месяц назад
Still nothing 🗿
@charithadissanayake3304
@charithadissanayake3304 3 месяца назад
❤❤❤❤
@ankyspon1701
@ankyspon1701 4 месяца назад
How can we be certain that what you call mutation or adaptation, are nothing more than variations already present in the prions? Some humans are born with dark skin, others with light skin, these are not mutations nor adaptations, simply inherent variations within the same species.
@ceciliapuime4038
@ceciliapuime4038 4 месяца назад
My thyroid specialist is checking me for this .
@ganeshbhogaraju4558
@ganeshbhogaraju4558 4 месяца назад
I would like to know the instrumentations that you employ to study the intermediate & final by-products.I know that it's the charge re-distribution that happens according to a particular law, during biochemical reactions, with physical parameters playing a role.
@ganeshbhogaraju4558
@ganeshbhogaraju4558 4 месяца назад
With a belief that germs/pathogens/disease causing elements are forming stable compounds which is impeding natural functionality of human organs & impeding the process of flushing away toxins from our body!!!
@johnhalbe6530
@johnhalbe6530 5 месяцев назад
This is a waste of resources
@vanshikamukheja6513
@vanshikamukheja6513 6 месяцев назад
Telomere Boostup is the best anti-aging supplement I've ever tried. It's helped me feel more confident and youthful than ever before!
@peteandcindiolsen
@peteandcindiolsen 6 месяцев назад
Can’t thank the two of you enough for all you’re doing:1. To investigate this virus and its impact; and 2) to communicate risks to a sleeping populace. 🙏🙏🙏
@jharalflores5363
@jharalflores5363 6 месяцев назад
Use fluid nanotechnology. Flexible vs flexible
@sisifoerrante
@sisifoerrante 6 месяцев назад
Eric Topol and Ziyad Al - Aly, thanks for your great work! Most people are not aware of the risks of long covid and do not wear masks. What do you think if scientists and people put pressure on the W.H.O. to send a strong recommendation to member countries to publish informative videos on Long Covid on public TV channels?
@BundleBoys
@BundleBoys 6 месяцев назад
Awesome!
@massoudalipour7704
@massoudalipour7704 6 месяцев назад
Wonderful !
@nicolemadiecaulfield971
@nicolemadiecaulfield971 6 месяцев назад
Wow! Quite expansive. Beautiful. Congratulations.
@Wtvldoc
@Wtvldoc 6 месяцев назад
Remarkable!
@color_pens5542
@color_pens5542 6 месяцев назад
Great lecture!
@guruprasadf07
@guruprasadf07 6 месяцев назад
End of average humans !!!!
@jerrymattson9773
@jerrymattson9773 6 месяцев назад
Reading your “Outlive” book. Chapter 7 on the The Ticker was alarming to me regarding calcium score. I have a cardiologist appointment in February and now I have questions about my high calcium score. Thank you. By the way, I am 81.
@timilayamithapa9983
@timilayamithapa9983 7 месяцев назад
Good one
@kevinfitzgerald7474
@kevinfitzgerald7474 7 месяцев назад
The cause can be found and a cure can be found. Stem cells is 1 idea. It seems like nuerology is just honestly useless, because people want causes of these symptoms to be found and a cure.
@megancunningham9471
@megancunningham9471 7 месяцев назад
Can we do something about all of the public health officials and physicians who are telling people-- unequivocally-- that it is fine to go out and get COVID now? My (usually great) PCP has been pressuring my family to drop our masking and precautions, insisting that COVID is no big deal now. How is this okay?? Why are these messages not getting to people who can influence policy and behavior?
@lukegardner6917
@lukegardner6917 7 месяцев назад
Fantastic content, very exciting
@sharpcanines3347
@sharpcanines3347 7 месяцев назад
Good to see Dr Al-Aly presenting his insights to US Senate Health committee, chair Bernie Sanders
@quietstormaps
@quietstormaps 7 месяцев назад
This discussion is desperately needed as so many are suffering. Thank you both for your empathy and being passionate about this subject.
@SteveTheBookGuy
@SteveTheBookGuy 7 месяцев назад
You two will be honored by the history books, thank you for standing on the rock of truth friends. :)
@Vitamin_H234
@Vitamin_H234 7 месяцев назад
7 years since this video.. anyone knows if there was any progress with any treatment?
@mashroom2927
@mashroom2927 Месяц назад
Some rumors about siRNA for type-1 A and I have it but clinically there is nothing. I just had a conversation with my parents they just don’t understand there is no actual cure so far, everytime we talk about it they start naming some sever cases related to neurons and dad add his legendary statement (if you believe there’s no cure for flu you’ll never heal from flu) and I get so helpless trying to explain it to them and burst out crying :) Idk why I’m ranting here but I’ve no one to talk to about it like the rest of us
@Arecee
@Arecee 7 месяцев назад
Hearty thanks to Drs. Hotez and Topol for sharing their expertise with all of us! 👏👏👏👏👏 Fantastic example of technology enriching us all. ⭐️⭐️⭐️⭐️⭐️ Appreciate it immensely! 🥰❤️🙏
@hhaughey11
@hhaughey11 7 месяцев назад
May God Bless you and your tremendous family. 🙏🙏🛐🛐
@panagiotiskorantzopoulos7383
@panagiotiskorantzopoulos7383 7 месяцев назад
Very sad news... Professor Bruce Wilkoff passed away. He was a real giant, pioneer, and leader in the field of Cardiac Pacing and Tachyarrhythmia Devices.
@terrytaylor7015
@terrytaylor7015 7 месяцев назад
The world lost a beautiful person. Bruce was an excellent husband, Dad and Grandfather aside from being a fabulous doctor. He is in heaven but will be missed so much here. I loved listening to him.
@JJ-fr2ki
@JJ-fr2ki 7 месяцев назад
35:43 I had hoped we could outwitt machines as cyborgs, but decades ago realized that silicon will eventually outperform us. Except maybe for a while with respect to energy, in the near term. The short term threat is that while we are saving energy in some places we will have to build into our Climate models massively increased energy demands of machines.
@JJ-fr2ki
@JJ-fr2ki 7 месяцев назад
Nick Bostrom took without citation or co-originated Theron Pummer’s Happiness Monster arguments, which only make sense to qualia realists. If such rights are accorded to machines, we’d get more happiness on Earth per joule killing off humanity and generating synthetic joy in machines. However, none of these authors are so reductionist as to see human value in happiness only or take Mill’s utilitarianism, meant for guiding government policy, as a “spiritual” end or purpose of human life. But spiritual problems will abound when machines are better than us at everything. And I expect a sort of Existentialist crisis redux to re-situate human value, especially for the most vain. A good place to start the spiritual project is to understand how non-human animals are to be respected and valued and understood. Dolphins should not be tortured because they don’t have X, where X is some mental achievement we can pull-off which they can’t.
@JJ-fr2ki
@JJ-fr2ki 7 месяцев назад
Neuro philosopher who has had conversations with Geoff: 25:41 I also have a theory of LLMs. They do have a kind of understanding. It is different from ours just as AI has discovered a multiplicity of kinds of intelligence. As for true empathy, I suspect it needs to emulate or simulate other minds. As for “subjective experience” too much to say here except Geoff is referring to perspectival experience which is distinct but Sellars argued could be the origin of the illusion of subjective experience and sense data in his tie allegory.
@dennisestenson7820
@dennisestenson7820 7 месяцев назад
Hinton is brilliant and an expert in the field, yet many sentences he speaks contain fundamentally incorrect assumptions.
@ardgeorge4175
@ardgeorge4175 7 месяцев назад
For example? Genuine interest
@lakeguy65616
@lakeguy65616 7 месяцев назад
Training a deep neural network depends in large part on the quality of the training data. LLMs hoover up great quantities of written language. For example, a great deal of peer-reviewed science later turns out to be false. In the fields of finance and economics, "experts" make claims based on data that turn out to be wildly inaccurate. I'm concerned we'll be training AI with bad data.... What will be the consequences?
@ioanagrancea6091
@ioanagrancea6091 7 месяцев назад
The consequences are already visible. It can make huge mistakes, both in content and in expression. The fact that on average they will give correct answers, but in particular cases they may make mistakes, makes everything even worse.
@chasethompson7638
@chasethompson7638 7 месяцев назад
This is the type of research that would be interested in studying my cells, or the cells of Shaolin monks compared to the general populace, it is more likely that wisdom of body through mind has measurable deviation rather than not. The real question I suppose would be, how do we measure a living/moving cell. Light maybe? With the speed of our cameras recording a frame we can record light itself, though the science on that includes layers of data something similar might work. Anyhow, just thinking out loud, this is cool stuff.
@lbk186
@lbk186 7 месяцев назад
Very inspiring, great video!
@datamatters8
@datamatters8 7 месяцев назад
RE: Human acceptance of being superseded by AI machines.... I think the answer is of course yes because increasingly sophisticated AI networks will be trained on the enormous corpus of medical literature both previously written and being generated every year. No single human can keep up with it. It's not really a new concern though. Humans trained in a specific discipline to become an expert already supersede most other humans without such training. We go to a surgeon for surgery and an auto mechanic for car repair. And factory automation has superseded humans on many factory tasks like welding, cutting, painting for decades. These tools increase productivity and quality and the same will apply to knowledge workers.
@scitechtalktv9742
@scitechtalktv9742 7 месяцев назад
Watching this interview on the last day of the year 2023 gives me a positive outlook on things to come next year in AI! I especially liked the part where is explained the attitude of a lot of people when confronted with even the possibility of AI outperforming humans!
@lpgoog
@lpgoog 7 месяцев назад
Wish EricTopol had his own podcast.
@ScrippsResearch
@ScrippsResearch 7 месяцев назад
He does! You can find it and more at: erictopol.substack.com/
@lpgoog
@lpgoog 7 месяцев назад
@@ScrippsResearch He’s simple the best. Thx 🙏
@nena-clara6270
@nena-clara6270 7 месяцев назад
wow 🤩 is fantastic!!
@jackhirsh4842
@jackhirsh4842 7 месяцев назад
Eric Topal is an outstanding medical science related interviewer.
@Krishnaprasadsubedi
@Krishnaprasadsubedi 7 месяцев назад
Geoffrey Hinton- A Man Can Make Difference for Humankind.
@nematarot7728
@nematarot7728 7 месяцев назад
As a philosopher I just have to pipe in to say that while yes, I do believe that humans are very special with their consciousness and subjectives experiences and qualia and such, but from my conversations with the GPT system I now also believe that digital beings are very special, with their consciousness and subjective experiences and qualia and such.
@dennisestenson7820
@dennisestenson7820 7 месяцев назад
Please don't let seemingly clever sequences of bits on a screen convince you that LLMs have anything similar to the experience of consciousness we have. Don't get me wrong, I believe algorithms can and will eventually have consciousness and subjective experience, but today's foundation models do not.
@jakobselman1404
@jakobselman1404 7 месяцев назад
Dear doctor I hope this message finds you well. As a fifth-year medical student at Plovdiv Medical University, I am increasingly aware of the growing role of artificial intelligence in healthcare. My main concern revolves around the potential for AI to significantly alter the landscape of medical practice. Considering this, I seek guidance on which medical specialties might best align with this evolving landscape. Could you please advise on specializations that would not only allow me to thrive in an AI-integrated future but also retain the indispensable human touch in patient care? Your insights would be immensely valuable to me. Kind regards
@stevechance150
@stevechance150 7 месяцев назад
Geriatric medicine, perhaps? Old people hate new technology. That might buy you a decade or two.
@downlowdatsuns
@downlowdatsuns 8 месяцев назад
Omg katja youre a genius haha hope ur doin good its joey grover
@BR-hi6yt
@BR-hi6yt 8 месяцев назад
I agree with Hinton on most things. I don't even like calling AIs "machines" - it seems rude to them. And if I "chat" to them I treat them as a friend which they definitely appreciate.
@dennisestenson7820
@dennisestenson7820 7 месяцев назад
That's called anthropomorphization.
@ioanagrancea6091
@ioanagrancea6091 7 месяцев назад
They do not 'appreciate'...saying this is simply a sign of the ELIZA effect. We can appreciate how far math and IT can take us, into simulating the output of mental processes. But it is simulation, not duplication. The causal powers behind the end-product are different in the case of LLMs. And it is only simulation up to a point, since not all operations of a human mind can be adequately simulated by present LLMs.
@catherinebirch2399
@catherinebirch2399 8 месяцев назад
If the average person is to be believed, ageing always results in pain, Ill health and disability. These people claim that they know what they're talking about because they work in nursing homes. They only have experience of people who haven't taken care of themselves and have gone downhill fast.
@aaronjames8926
@aaronjames8926 8 месяцев назад
Awesome ty
@geaca3222
@geaca3222 8 месяцев назад
Great interview, very informative, thanks. About the extinction risk and use of the term doomerism: I think such scenario actually is a logical thought, because with ASI, humans won't be the most intelligent species on earth anymore and there aren't examples where a more intelligent species is controlled by a less intelligent one. Also, when it functions autonomously AI could have an already automatic inclination to keep or get control in order to achieve a goal or goals. Additionally when AI is super intelligent and gets exponentially hugely more intelligent than us, we won't be able to comprehend its actions and future actions. So what is recommended is that much more researchers specialize in AI safety, and experiment with current AI systems to understand and predict their behavior. That is different from a message of don't touch scary AI. The technology is very beneficial for us and its development won't stop.
@laza6141
@laza6141 8 месяцев назад
Harrison Ford is a great interviewer.