How to download sir

So glad I stumbled upon this video.

Sir can we add our own designed molecules for pharmacophore mapping

thank you

Hello sir, I need your help in interpreting a NMR data. Can you help?

Sir, how to perform docking using the homology modelled protein and how to select the binding site in it

How Does validate docking of a protein that does not have co-crystalized ligand?

if the molecule have more than 500 molecular weight so how we can dock

Thank you Sir very Good This is rigid docking or flexible docking sir ?

When I try to display a 2D diagram of the ligand in Discovery Studio, I receive an error message saying 'Ligand is not a single fragment' and I don't know what I need to do. I need help to resolve this issue.

Hi bro dushyant reddy Please send me your contact number

Thank you very useful

How to dock only one ligand, if two ligands are present in a protein imported from Database, For example : 5ARG this is having two ligands, but i want to retain SAH ligand, other ligand should be docked. Please comment you answer can solve my difficulty.

Do we need to prepare the ligand and protien before uploading onto cluspro?

I have an out of context question, can you demonstrate Lumo properties of a methyl side chain against an amine side chain let say in the activity of a propionic acid group which is responsible for antiinflammatory activity.

Thank you very much for this well articulated video. I am new to Pharmacophore Modeling and I have perfomed docking on a protein and ligand (drug), so my question is how do I know which pharmacophores are responsible for the interactions between the two?. Can I assume that the descriptors I am getting after loading the two before "submit query" is what is responsible for the interactions?. If so how do I download the table of this descriptors ? and picture of my protein-ligand complex?.

Hello sir, can you please explain how to get the mol format of ligand and protein that we can use in pyMol for RSD value that you explained at the end of the video? Can you make a video if possible please

thank you sir. 👍

NICE SIR ..I Like your way of teaching....

Thank you Sir for such a good video for making is understand about docking

Dear professor i need your help please, I performed docking with Schrodinger and i want to validate my docking, so i need to calculate RMSD. But i didn't know how to do that with discovery studio, how to get the structure of r docked complex : protein- ligand

Sir gene related disease ka receptor kese find kre ge for drug design plz guide me

how can the pharmacophore be generated only with the protein structure assuming we know the active site residues but have no ligand-protein structure

So one question sir, when we redock the same ligand we need to get the docking results such that over docked ligand comes exactly over the actual bonded ligand.........so we have to change the grid box dimensions so many times till we get exact allingment of redocking. Am I right?

Sir qsar study k liye koi free software available h kya

Sir, Pls tell us how can we select any protein for docking of any derivative?

need your help regarding Interpretation of P-NMR

Sir I want your help

Sir kindly, give a tutorial on RMSD calculation of protein n co crystal using discovery studio please

Hi Dr Dushyanth It's pleasure to write you. actualy i have a problem with Zincpharmer. could you help me to solve this problem. Error connecting to search engine. Please try again later and if the problem persists, contact the administrator. keep in contact. best regards Mahmoud

This was really good! Thank you!

sir could u tell me how to visualize protein protein docked complex in dsv

Hello sir, I hope you are doing well. Could you give me a step-by-step from first how to do pharmocopore modelling and how to make the structure from pharmacophore modelling results? Thank you

How can we download molegro virtual docker

sir only hydrophobic and h-bond visible in LigPlot? hw can we view other interactions

Hello sir

what for those who dont have paid version of discovery studio

Hi sir Experiment repeat krne se results alg aarhe hai. Can you please guide regarding the same? Thank you so much!

Sir vo x ka x thoda detail me bato na

Hi sir one doubt The active site and binding site are the same or not?

What is selection criteria for Protein selection from PDB for Docking

I have optimised my ligand with Marvin sketch, and added gasteiger charge even though error comes that partial atomic charge had not added on ligand , can u please tell that where is the problem ?

Sir the hit molecules after submit query...how to do docking for best hits compunds other than the CLC GENOMIC WORKBENCH.. as this software is paid. Please can you tell some other softwares that are free. Thank you.

Thank you so much for your video, I would what to know after I got my hits , how do I decide which one to choose for further study? Based on SAR ? or best overlay? Thanks

How could I get other related videos of ur channel

It was really very helpful....wish to see your informative videos again sir

Sir can you share your mail address, so that i can send you my query?

Nice lecture

a lot of love for ndian people with their generosity

Sir, is there any validation step required after performing this experiment.