On a mission to disseminate information to the community and bridge the gap between academia and community oncology in this rapidly changing field of hematology & oncology. Drs. Rahul & Rohit Gosain interview world-renowned hematologists/oncologists to present the practice-changing data in a small bite-sized format where one could immediately apply that information in their daily practice to provide the best cancer care to their patients close to home.
That was great. Thank you. When are you going to do the NET p and GI treatment with Mark Lewis? He is great. Can´t wait. I listen to you guys almost daily in Spotify
I'm kappa light chain MGUS, but it's just 38.69, ratio 3.06. At what point would a bone marrow biopsy be done? When my ratio reaches 100? I understand the "watch and wait" in MGUS and SMM, but I thought a baseline BMB was standard after MGUS diagnosis via serum.
I've been just diagnosed with rectal cancer after a biopsy during my colonoscopy. So far I've had a CT scan that showed 2 lymph nodes one 5mm and the other 6 with no spread to any organs. The Carcinoma is in the mid rectal area 5cm in length and I believe it is the MSS type tumor. I'm getting a MRI the second week of June I believe to get a better look at the lymph nodes. From what my surgeon said, I will get chemo/radiation, then if it didn't totally disappear which I don't think it would from that, I would get the surgery with an ileostomy. Then most likely chemo after that. All this seems like overkill to me. I'm so unsure if what they are planning is the best thing to do. Do you have any input or questions I should ask my Oncologist and Radiologist..
I was enrolled in manifest-2 protocol in Rome. My life became miserable because I was always ill. I stopped after the virus herpes zoster was riactivated and I suffered a sever facial paralysis. After a year I already have a parcial paralysis and balance problems beacause the VII and VIII cranial nerves were severy injured. I accepted to be enrolled because the doctor told me that otherwise I was going to die for leukemia. That was not true! I didn't have the intermediate-1 grade of myelofibrosis! I only had pre-myelofibrosis! Now I am well cured for pre-myelofibrosis in another roman hospital, only with oncocarbide and booldlettings when necessary, exactly as before I was enrolled in Manifest-2 protocol. I have never have anemia, sweeting or other sintomi, except a bit of fatigue. I've spent 10 thousand euros for the cures. Now I've filed a lawsuit against the hospital. But the law in Italy is really slow and I'll wait 10 years to have justice. The bad news is that I am hughly and parcial disabled, the good news is that I'm not going to die soon as I was told by the doctor who enrolled me in manifest-2!
I'd like more info, my husband was diagnosed in 2017 without biopsy... he chose to do nothing with a PSA of 80 & rising . His PSA is now over 200 & PET Scan shows it's spread to bones & lymph. PLEASE HELP, NEED ADVICE ON WHAT TO DO NOW, I don't want to loose him !
They mean kidney damage, due to light chain (proteins) deposits, that are dumped in the urine. They also may be referring to amyloid proteins in the heart (Amyloidosis) and kidneys.
Those types of drugs will not penetrate cancer cells without a lipid vehicle. Researchers have had promising results with mice by attaching a benzene molecule to mebendazole but you cannot do that with humans as benzene is a known carcinogen.
Good morning sir, To use Sacituzumab in metastatic setting there must be atleast failure of two prior therapies, but our algorithm does fit that way. We are directly opting it after first line failute
Absolutely worthless video if your a patient. Might be fine for bunch of docs sitting around a table. Nothing but a group of intellectual dweebs talking to one another in language a patient has no hope of understanding.
As an MBC/PIK3CA patient on Truqap/Faslodex, I think a lot of prescribers have limited educational material to offer us (I am fortunate to have an excellent oncology team, but others in our support group have been told "It's so new we can't really tell you what to expect") Can you recommend any educational sites for patients on Capivasertib? Thank you for this video, and for your work, Dr. Rugo.
MM is caused by the Herpes virus family. If doctors performed a PCR test on the BMB for all eight herpes viruses, they would be taken back by the positive results of the BMB for at least one of the herpes viruses. Take patients with a recent SCT as an example, what do doctors prescribe right after the SCT? Acyclovir!!! Why!? Because the herpes virus wasn't destroyed by your SCT. And now it's back even stronger because you weakened your whole immune system! Hence why patients relapse within a year following their SCT once they get off the Acyclovir. Don't believe me? Look at the remission rates of patients that remain on the Acyclovir vs those who didn't following their SCT. Here's some more food for thought; why are there so many MM patients who's spouses end up with MM as well? It's not hereditary, we've already determined that. It's because the herpes virus can be transmitted so easily. It's found in semen, breast milk, saliva, vaginal secretions etc. This is also why there's so many MM patient's children, brother's, sister's, mother's or father's also get MM. The virus is being passed down generation after generation. It's also why we see so many young people, including myself getting the disease. The MM communities I'm part of and hundreds of patients who've confessed to a previous critical herpes outbreak/experience years prior to being diagnosed is blatantly obvious. Let's dive deeper, what cells does EBV use as a host to replicate itself? B-cells, right? What cells do B-Cells create? PLASMA cells. Could an overabundance of PLASMA cells be caused by EBV?? Gee I wonder... Still don't believe me? "Fresh peripheral blood mononuclear cells (PBMCs) from 139 MM patients who had been diagnosed and treated from January 2010 to May 2018 and 50 PBMC samples from healthy donors were obtained. PCR was carried out for detection of EBV-DNA. The results indicated a significantly higher EBV-DNA concentration among 139 MM patients compared with healthy controls (P<0.05)." (www.ncbi.nlm.nih.gov/pmc/articles/PMC6822490/) Jump on Acyclovir and see if your numbers don't improve.
Im 55 IgG Lamda 0.3, and 0.4 = 0.7.. All other numbers are good. Ya, I have 2 M Spikes found by accident looking for something else. My Numbers stayed the same for a Year. So, I dont go back until Aug 2024. Great Video. Very Informative. Thank You!!
Is it possible to email Julie? My Mother is dealing with recurrent lung cancer and is on a targeted therapy pill. She read Julie’s article in the Boston Globe this morning 2/7/2024. I am her daughter Susan and caregiver. My Mom would love to reach out to Julie. Thank You, Susan
