Brought to you from the clinical education department at the University Hospitals of Leicester, this channel aims to serve as a library of short videos on an array of important clinical topics. The short lectures are about 8-20 mins long and serve as case based approaches. The guidelines adhered to are a mixture of local and national guidelines and we would always recommend looking at your own trust guidelines in clinical practice. All videos have been thoroughly checked by all levels of doctors including a consultant in that field for each topic. Links to the videos are also available in the Dr Toolbox app.
My son, 10yr old, 4wks ago had haemoptysis, 600mls, 2 days later 200mls, 2 days later 100mls. Univentricular, Tricuspid Atresia, fenestrated TCPC, SPO2 mid 80s %. Warfarin & lisinopril. Normal obs, TXA, Stopped Warfarin, now on Aspirin. Developed chest infection post haemoptysis. No diagnosis as yet! Lots of arterial collaterals. Planned closure of fenestration in next month. No brochoscopy. No CT angiography.
If LAMBDA is 122.52 & so ratio is 0.14 but IgG is high 19.12 Paraprotein is 6.2, TSH 6.6 , ESR 34, Vita D3 v low 14. fatigue, back neck shoulder pain, numbness tinkling , all since 6-8 months, acid reflux- since 5 months Is this Myeloma ?
Thank you for posting this, so I can actual see test results. I’ve been classified as having Kappa Light Chain IgM-MGUS, that seems to be slowly progressing towards NHL or WM. I had a brother who died from MM. I’m in very poor condition health wise because of multiple birth defects, so my outlook is grim at best. I’m a male,79 my brother was 72 at death. I had two precancerous moles were removed in 2013, one by the left side of my nose, the other in the left side of my neck in the back. I see an Oncologist and Hematologist bi-yearly. Any advice for me, my bloodwork showing an slow upwards climb in this wait and see method?
No it's more liver related disease is my understanding...my igg is 18 and I've suspected myeloma but he says anything under 30 is mgus its all rather confusing
Yes, kappa and lambda free light chains can increase due to immune system activation like infections or autoimmune disorders. The ratio typically stays normal in polyclonal responses. Monoclonal proteins excreted by cancerous cells cause the ratio to get abnormal-typically.
Many thanks for the video. Would just like to point out that potassium should almost never be added to a fluid bolus, as it would be infused very quickly which is risky especially if the patient is very small
I need to see this doctor, I'm currently experiencing this and it's driving me crazy. I've been to hospital and they gave me antihypertensive drugs which are yet to be effective. The pain I'm going through brought me here. How do I get in touch with this doctor please?
Me too. I was rushed to AnE last week with these symptoms and diagnosed with a migraine. After the Dr (a specialist) told me that there are several types of migraines I did a quick research on their symotoms and causes (which did not match mine). That then lead me to research the different types of headaches which lead me to thunderclap headaches and symptoms that matched mine. Now to get the Drs to look into this ...
