Miltenyi Biotec is a global provider of products and services that empower biomedical discovery and advance cellular therapy. Our innovative tools support research at every level, from basic research to translational research to clinical application. This integrated portfolio enables scientists and clinicians to obtain, analyze, and utilize the cell. Our technologies offer solutions for cellular research, cell therapy, and cell manufacturing. Our more than 30 years of expertise spans research areas including immunology, stem cell biology, neuroscience, cancer, hematology, and graft engineering. In our commitment to the scientific community, we also offer comprehensive scientific support, consultation, and expert training. Today, Miltenyi Biotec has more than 4,700 employees in 23 countries - all dedicated to helping researchers and clinicians around the world make a greater impact on science and health.
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Thank you for this information. I wanted to live in the FDA community in MD. Maryland is very progressive. Good manufacturing is essential. Consumer journalist document everything. With AI and drone introduction’s everything is on the intrepol or internet. MR 12 good morning.
Thank you for showing the equipment and a real life sample being filtered with the kit. @Miltenyi_Biotec please add more videos like this for new users. This is more useful than the cartoon/diagram/cgi-only videos.
I think u have to use the plant Nuclei extraction you have to use tris HCl 0•4 M pH 7.5, always with ice bath and filter pores 20 micrometers this protocole is used for Allium cepa roots
Our Nuclei Extraction Buffer (130-128-024) has been validated for a wide range of fresh and frozen mouse and human tissues. We have not tested the Nuclei Extraction Buffer on fungal culture, I am afraid. However, we think that the buffer may be applicable to a wide range of species.
During a manual magnetic cell separation, the negative fraction will drip by gravity and it is necessary to perform the 3 washing step and to collect them as well as part of the negative fraction. Hope, we could help you with this. If you need further help, please contact your technical support technicalsupport@miltenyi.com
What is this machine doing? Vibrating the cells? Shaking? What's the approximate rotation area and rpm? What is this machine doing that just shaking the cells at high RPM is not doing?
Good morning, if you want further information about our Sample Preparation portfolio, please visit our website: www.miltenyibiotec.com/products/macs-sample-preparation.html?query=:relevance:allCategoriesOR:10000088%23OnJlbGV2YW5jZTphbGxDYXRlZ29yaWVzT1I6MTAwMDAwODg%3D
Another webinar where’s it’s impossible to understand anything. It looks these type of webinars are dominated by people with poor linguistic and communication skills.
Hello Nolab, maybe we can help you with further information on our website or you also can contact your Support Team Miltenyi Biotec Technical Support Global <technicalsupport@miltenyi.com> www.miltenyibiotec.com/DE-en/lp/immunogenicity-assays-in-drug-discovery/solutions-for-predictive-immunogenicity-assays.html
I understand that when Car-T therapy is used for chronic Lymphocytic Leukemia,it wipes out all B-cells,what about NK-cell therapy?Would it leave the heathy B-cells?
Thank you for the question. NK cell-based therapeutic strategies in chronic lymphocytic leukemia (CLL) and in other malignancies aim to potentiate and/or restore NK cell activity or to provide patients with functional NK cells able to kill tumor cells. According to Sportoletti et al (NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications - PMC (nih.gov)) ‘’in vitro studies have shown that allogeneic NK cells, after expansion/activation with an optimized protocol, are able to kill CLL cells independently of KIR-HLA mismatches. However, although allogeneic NK cells do not mediate the GvL effect in a CLL-HSCT transplantation setting, they, unlike T cells, lack the potential to cause graft-versus-host disease (GvHD) thus representing appealing and safe candidates for adoptive immunotherapy for CLL.” Your Miltenyi Team
Hello INGSOC, to our knowledge and according to the published references there are some clinical trials using NK cells in combination with other drugs treating esophagus cancer. Here you find the references: www.ncbi.nlm.nih.gov/pmc/articles/PMC8113860/ and www.ncbi.nlm.nih.gov/pmc/articles/PMC8630679/#!po=20.7692 Your Miltenyi Support Team.
Hi Carlos, yes absolutely! Our gentleMACS™ M Tubes can be used to extract proteins with our gentleMACS. If you want to analyze the cytokine secretion by specific cells we can also recommend our MACSPlex Custom Cytokine Assays. Our Miltenyi Team
Hello, yes you can. Here are more information to our products for Research and clinical applications for hematopoietic stem cells (HSCs) www.miltenyibiotec.com/applications/hematopoietic-stem-cells.html
Dear Wayne, in this video we used the tube sealer of the CliniMACS Prodigy, our instrument for automated cell processing. However, if this device is not available in your labs, there’s are a number of sealers from other companies available on the market. Best, your Miltenyi Biotec Team
Hello Kriti, you can use the following application Programs 1. for human tissue: h_mito_tissue 01 human and for 2. mouse: m_mito_tissue 01 mouse C 1 - 1270
