限制正常手臂活動(用吊帶或包紮)，一再重複失能手臂的運動，可能激發控制失能手臂的中樞神經元細胞重整網路(如突觸調整重塑，synaptic plasticity, 或樹突，軸突增生)，招募先存並行網路取代或補償損傷網路，甚至新生細胞參預修補(nrurogenesis)，可能提供一些神經可塑性的理論基礎。參閱： 1) Adult Neuroplasticity： More than 40 Years of Research. Neuro Plast 2014; 2014: 541870; 2)Effect of Constraint induced movement therapy on upper extremity function, 3 to 9 months after stroke. 2006; 296(17):2095; 3)Constraint induced movement therapy as a rehabilitation intervention for upper extremity in stroke patients, systemic review and meta-analysis. Int J Rehabil Res. 2016; 39(3):197; 4) Rehabilitation and Neuroplasticity. Am J Therapeutics. 2011; 18(1):70.
