Sir, you did a really good job in this video. It's been a year since i started learning bioinformatics but I was never sure of what was going on until I came across this video. I decided to comment before even finishing the video because I already got 90 percent of the concept. Thanks a lot.
Thank you so much! I'm reading a publication about MSA and your videos helped me understand sequence alignment! Very wonderful explanations - by far the best video about sequence alignment on RU-vid.
You explain it so well! But i wanna know if there is any reliable software recommend for sequence alignment since i found so many different software online
How is this calculated in bayesian terms? What are the assumed priors? This must be an infuriating probabilistic problem, if we can't even assume the distribution of mutation frequency?
Glad that you like the explanation. I don't have an implementation in Python. I did ask students who took my course to implement the algorithm, and they have done it using different programming languages.
Why you not used word from the sentence I think it's better until we get the idea clearly I feel like dizzy from these alphabet. Please keep it like examples words am really need that way to understanding Tq so much
didnt understand the 2nd rule can anyone explain plz or does it mean that at a single position in both the resultant sequences must not have a gap ATT-GC SOMETHING LIKE THIS? GCT-AC
