I probably find you the most easy to understand lecturer on RU-vid. You don't make things unnecessarily difficult, you stick to the point without adding extra information. Together with Khan academy, arguably the best channel for biology on youtube
This is so helpful! I read my book, listened to my lecture, and went over my notes and this just never made any sense. You made this so easy! Thank you!
This really helped! Although the way we were taught, SPATIAL summation involves multiples EPSPs happening SIMULTANEOUSLY from 2 or several more presynaptic connections with the connections of the receptive zone of the postsynaptic neuron. The graph we were shown looks completely different, as since all of the EPSPs fire at ONCE, it goes up past the threshold suddenly, rather than in small increments like temporal summation
According to the Elder Scrolls, they speak of something to do with the concept of Zero-Sum, but I went blind before fully understanding the necessities of achieving it. I'm a Moth priest who studied the Dragonborn Elder Scroll, mostly. I won't be retiring any time soon, I'll be on an expedition to Morrowind to learn as much as I can of Vivec's biological, spiritual and metaphysical aspects of how he Zero-Summed, achieving CHIM, though through mechanical/magical means (Zero-Summing requires a deep understanding of existence, not earthly things).
Yes we saw it that way as well. For temporal, the graph goes up 2 times and reaches the point X for example; for spatial summatiıon, the graph goes straight to X
@Chaldanaya Sure. The importance is to allow the stimulation to bring the membrane potential of the axon hillock to threshold. Once the membrane potential reaches threshold, an action potential can happen. Each neuron is receiving input from multiple neurons, and it takes all of that input and decides whether or not to start an action potential. It basically combines the inputs and generates an Action Potential if the sum of all Potentials is large enough. Hope that helps!
@aydn9 That's awesome. Glad it's helping. With an insect that landed on your skin, you are getting stimulus coming from the same source that isn't moving. The stimulus remains, but same source, same receptors stimulated over and over. That is temporal. With a crawling butterfly, you have different receptors stimulated (in addition to the same ones for a certain period of time). Different input is spatial. Hope that helps. Gotta run ;)
@stareleades Unfortunately, Leslie is no longer taking requests for specific videos, but he will definitely get to more systems and more Biology topics in the future. He has many to work on at the moment. So stay tuned for more. :)
My professor did not cover this subject in class however it is on the departmental final. Luckily i found your video, very clear and concise information. Just wanted to say thank you!
From this description it one could make an educated guess then that the "pins and needles" feeling after a limb wakes up from going numb ("fell asleep") is mostly due to the nerves increasing their temporal firing to reestablish contact with that body part's nerves. It's not felt when the limb first reawakens but after the nerves of the limb reestablish their normal levels (of firing and response) and the excess firing that was triggered to compensate results in the pins and needles feeling until the excess firing wears back down (seems very likely a negative feedback loop at play there).
hi, I'm from Germany. I used your video to understand this topic due to there are no good german videos.... You speak a understandable English and you present the topic understandable...... greetings from Bavaria :)
@Jaggamuffin1 That is correct. I'm simplifying in this video by just showing one synaptic terminal, but there can be many on 1 neuron, and they would all be releasing NT when there is an action potential.
Great videos. Awesome to hear a different accent backed by a brilliant brain. Far too often, TV shows, dvd producers, academic institutions, tend to promote the French, Spanish, Italian, German, American (Anglo) accents, and this leads to most people being brainwashed to think that the only intelligent humans come with a Spanish, Anglo accent. Thanks for helping to educate other students/teachers/producers that "a person's accent doesn't indicate their intellect nor human value as an educator/human friend".... Keep up the great work.
I'd be interested in seeing you explain how EPP and NMJs differ. Thanks for your effort 12 years ago. You're a teacher that reminds the world the power of excellent teaching.
I'm so glad this was helpful for you, @myranoorwaheed2501. My goal is to make biology as clear as possible. That's a great topic suggestion. I'll add it to my topic ideas list. Also, if you want more explanations like this, make sure to subscribe - I have a ton more on the way!
Leslie, Thank you so much for your videos. I have a very hard time with understanding how my professor explains things. You ALWAYS do such a great job of explaining things to where I understand it. You make it simple and interesting. Thank you, thank you, thank you! :) You are AWSOME!!
Your explanations are perfect- to the point, simple, easy to understand without a lot of unnecessary verbiage to confuse me. Great work! :-) If I get an A on my final, some of the credit goes to you!
omg.. YOU ARE A LIFE SAVER!!!! Wow wonderful video! I really understand it now. reading it from notes and a textbook is nothing compared to visual and explaining. It really feels good to actually know whats going on now :) thanks a lot
EXCELLENT!!!!!!!!!!! LOVED IT! made it much easier for me to understand. I have read this section on my textbook several times, but it didn't make sense to me. Thank you so much! Continue with these great explanations, you make a difference in understanding and also in a grade for a paper ;)
Thank you for this video! I could not understand what summation was the way my A&P book explained, but it totally makes sense now.... and it seems so simple now ;)
@EvelynNLB Sorry, Leslie won't be able to get back to your inquiry. He's been very loaded at the moment with a lot of work. Please do stay tuned though as he'll be adding more Biology videos in the future. Thanks!
@pinkash1283 Glad to know that you found value on this one. You might also need other Biology videos and resources. Just head on to our site for more of them :)
@Emelyme Hi, I don't think that summation is necessary for every action potential, but I'm not 100% sure of that. Maybe someone else can chime in. I would assume that if a stimulus is large enough from one input, it should be able to reach threshold.
There's potential called threshold potential (-55mV) when reached affects certain voltage gated Na+ that when opened give rise for rapid change in membrane potential due to entering of sodium into the cell.
@anjali1129 Lol! Well, that's good to know! Thank you for watching this video. You can go and check our other Biology videos at the site. We hope you'll find value in them as much as you found one on this. Have fun!
The Elder Scrolls speak of something to do with the concept of Zero-Sum, but I went blind before fully understanding the necessities of achieving it. I'm a Moth priest who studied the Dragonborn Elder Scroll, mostly. I won't be retiring any time soon, I'll be on an expedition to Morrowind to learn as much as I can of Vivec's biological, spiritual and metaphysical aspects of how he Zero-Summed, achieving CHIM, though through mechanical/magical means (I believe Zero-Summing requires a deep understanding of existence, not earthly things).
