075-Cyclization of Sugars 

You saved my semester, thank you :)

Thank you for posting these Biochem videos! They are helpful!

very lucid in explaining, thanks a lot

Very helpful, thanks!

hi, this video has been really helpful, but can you pls explain why is it that the O on the 5th Carbon attacks the double bond. Is it impossible for the other oxygens to carry out nucleophilic attack?

The chair projection of D-a-Glucose, is the OH equatorial or axial? To me it should be axial since OH is pointing down in Haworth representation. Thanks

Why does cyclization of d glucose give two isomers of a and b d glucose?

Thinking alpha down and beta up is not entirely accurate. That would only apply to D-sugars. The most accurate definition is if the -OH on the anomeric carbon is on opposite planes of the terminal -CH2OH group, that is alpha. If the -OH on the anomeric carbon is on the same plane as the terminal -CH2OH group, then it is a beta sugar.

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