How does 5-FU(Fluorouracil) work to treat cancer?
How does it work in cell cycle?
We can confirm the RNA and DNA synthesis first, and learn the process of 5-FUto treat cancer.
(Reference)
1.Longley D. B. et al. "5-fluorouracil: mechanisms of action and clinical strategies". Nat. Rev. Cancer. 3 (5): 330-8.
2.Álvarez, P. et al. "5-Fluorouracil derivatives: a patent review". Expert Opinion on Therapeutic Patents. 22 (2): 107-123.
3.Vinayak Singh, et al. Complex Mechanism of Antimycobacterial Action of 5-Fluorouracil. Cell chemical biology. Vol 22(1) 2015 page 63-75.
4.G.JPeters, et al. Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism. BBA vol.1587(2-3)2002 page 194-205.
Music; made by myself, used garageband
Picture(DNA); Pixabay
7 авг 2018
