(SORRY FOR BAD ENGLISH) easiest is seraphine with build crit, ability haste and proyectile (her passive gives you a chance to duplicate proyectiles) and then proyectile weapons that deal crit and shoot proyectiles like uwu bot or boomerang, etc. You also build health (more shield from E) and armor (you get the blue cube shield that blocks 1 instance of damage everytime, it's broken with ability haste and when evolutionated), don't forget to use R to get invulnerable for a few seconds if you're about to die. To evolution all your cards you must dont pick up 5 cards from minibosses. You can do this when around 8 minutes instead of at the start so you are not that weak. Good luck :)