ALT, AST, ALP & GGT (Liver Function Tests) - How to Interpret 

For me, my higher than normal liver function tests revealed a silent problem that was going on. My ALT and AST started getting out of range growing higher each year (Over a three year period by the lab work results). My ALT hit 153 and AST was 88. ALT by the chart was over 113 past normal and AST was 40 points over. So what was causing my Liver to start hitting the panic button??? Well, an ultrasound of the liver showed the Renal Cell Carcinoma that was growing on my right kidney. MRI showed the tumor growing on my left kidney. From what I have read, the ALT enzyme reacts when the RCC gets into the renal artery. Well, two surgeries later, loss of right kidney and a piece of my left my numbers are back in range. I was in good shape, non-drinker, non-smoker, exercised everyday. If your numbers are getting out of whack and your Dr's tell you to stop eating fast food (That's what the dude told me, turned out to be Cancer) just make sure to keep looking at the problem. My bad Liver Function tests saved my life because I kept trying to find out why it was bad and I indeed found out why.

All I can say is WOW! I could not understand these enzymes any better. I like the fact that you started by highlighting where each one of them is found and that made it very easy to Interpret the results. Im officially your subscriber from now.

Like everyone else here is saying - this is an amazingly digestible breakdown of liver enzyme analysis. I actually feel like I have some rough idea of how to interpret values now. Thank you!

The best video out there on LFTs!! Thank you so much!

No one can do better explanation than this. i really find value

Fantastic video. Thank you

This is the best explanation ever…..

thank you so much for this video and the important information included herein.. had lab tests done and both alt were aboeve normal, the 2nd result was even higher than the 1st and ast also was above normal but abdominal ultrasound shows normal liver impression..

Beautifully done, sir!

That truly was the best and most informative, easy to understand explanation ever. Thank you!

very clear explanation, thank you very much

Thank you so much.... Best I have ever seen.

Excellent presentation to Doctors and Patients

Thank you so much for the clear explanation!

Excellent presentation! Thank you very much!

This is awesome. I have actually learnt alot from watching this and am glad I found your channel. Please can you give us tutorials on lipids profile as well

Very helpful video. Thanks a lot. 👍

Mine was due to alpha1antitrypsin deficiency! I think everyone with the high levels should be checked for this today! It’s not an expensive test and needs an early diagnosis when possible🙏

Excellent explanation. Thank you.

Well explained to my understanding. Thank you very much

Genius. amazing explanations

U absolute gem Thankyou

Excellent. Was diagnosed with autoimmune hepatitis and treated most of last year. Turned out to be an infected gall bladder.

Wonderful explanation. Keep sharing more

Your interpretation is amazing, i ws able to grasp it easily. Thank you so much, God bless you. Hadiza from Nigeria.

Thank you thank you thank you! ❤️

Wow thank u for this eloquency 👏🏻👏🏻👏🏻

Thank you so much for this very informative video.

Wow , Awesome thank you Doctor

It was more than awesome! Keep up!

Thank you... you saved many hours of my study time 🥰❤️

Thanks great summary.

thank you. really really useful.

Excellent explanation❤

great explanation, thank you very much

Very nice explained

Amazing explanation!

Awesome video! New sub man

Good explanation, thank you

Thanks. good and perfect

Very good explanation...❤

Thank you for this video.. God bless 🙏

Great vid Thanks!

In India, we frequently find ALT values in thousands, 2 to 3 thousand , in case of Viral hepatitis

Good job

ty 4 the awesome video

Good explanation, animations superb.

Thank you!

Brilliant

very helpful thanks

Got ur subscription deserves it

This is the amazing video 🎉

Excellent explanation.

Just amazing

excellant teaching

I suggest you look into anti dressants. I have MTHFR c677t. My liver detoxes 70% slower. I allowed myself to be put on an anti present well butrin an enzyme I a had under control rose.

Great lecture.

Thank you, that was very easy to absorb 🙂

Thank yo so much

Thank you so so much 😍😍

Really superb

Very informative

Concise and to the point. So helpful! Thank you so much!

Hight GGT only is : Auto brewery syndrome is also known as gut fermentation syndrome and endogenous ethanol fermentation. It's sometimes called “drunkenness disease.” This rare condition makes you intoxicated - drunk - without drinking alcohol. This happens when your body turns sugary and starchy foods (carbohydrates) into alcohol.

Thumbs up👍👍👍

Well explained

Best video

Thank you so much for sharing this info! I just received my blood test result and have high ALP. The rest are alright so now I can decide to do a bone scan first just to make sure everything is ok. Cheers!

what about NAFLÐ (non alcool fatty liver disease)?

What could a high AST:ALT ratio (>2) with low to normal GGT suggest?

wow. 👌

You got a subscriber.

Very clear video. What is the potential diagnosis please if there is an isolated abnormal ALT of 127? I am talking about a young nondrinker who does not so suffer from haemochromatosis. I mention haemochromatosis because his serum ferritin is also high, as is his creatinine. No viral hepatitis detected.

Doc my ast is 21.3 and my alt is 26.5 which the ratio is .80 that is less than 2, but my upper right abdomen is painful and the right side of my ribs, what is that doc? Could you enlightened me for that situation

Upon getting my Bloom simple tests results.....de hace discovered i am experiencing "LowLevels of GamaGlutamylTransferase" I am uncertain what that implies....i do know i am experiencing VeryLowEnergyLevels????

Could raised ALT and AST be due to beta blockers and/or anti-coagulants?

My heart just keeps thanking you and thanking you Dr Igudia for all you have done for me, you gave me your words that you could heal any sickness or disease, thank you for permanently curing me of my Hepatitis B disease you are amazing

Great analysis but i suggest you to use better microphone for sound quality

My ast level is 36 and alt is 18 , but ast alt ratio is 2 , is there any problem?

So with a small raise in GGT on blood test but all others are fine is most likely cause I drank a shit ton of alcohol 4 days before during a crazy weekend?

my blood tests came back and everything was good except my ALP was very low - what does this mean? The lab did not explain anything. Can this be the reason for Rosacea and/or weight gain? My AST and ALT were normal

Thanks sir 👍👍

Amazing video, thank you! if GGT, is raised and ALP is normal, accompanied by elevated AST and ALT (AST higher than ALT, but both raised), what is the likely outcome for that?

Can anyone plzz explain me the difference between liver infection and liver damage???

i am hep b patient what test results interpret that i am in danger or out of danger?

May God continue to bless you Dr Igudia for always listening to me and always being there for me, your medicine was top notch, thanks for taking away my Hepatitis B Virus pain. I'm grateful doctor

What about Liver Steatosis? NAFLD?

ALT is in muscle too

What does it mean if there is no liver damage? Does it mean that it is functioning well?

What about alkaline phosphatase at first test 182 now 211, 5 weeks later and alt at 48? Thoughts? Everything else seems to be good

Wishing you had included a low ALP result. Otherwise, great information.

My ast 52.8 and alt 86.1....sap 103 pl suggest it's ok

Alt 40. AST 30. Alp 47. Ggt 85u/l. Have not drank alcohol for 5 years. What’s up with ggt being 20 points out of range?

Normal AST &ALT but alightly high GGT ( results 43 &51) can chemo do this?

My test include AGPT and SGOT not sure what it means.

What if my ast is slightly elevated am I okay ??

I was diagnosed with fatty liver but my doctor said it is unnecessary for me to have a GGT test performed. Is this true?

My alt is 20 and my ast is 20. This is the second time they have been the same. Is the ratio important to look at? My ALP is within normal limits and my doctor didn't comment on it so I don't know if I should bring it up. I have been diagnosed with fatty liver in the past with NASH 1 but I lost about 50 lbs since then but gaining 15 back. My last CT Scan did not show fatty liver so I am just concerned about the ratio since my 15 lb gain.

Ast Alt ratio is 1.35 normal or not.

AlT - 37.0 U/I is normale range?