AS Biology - Carbon dioxide transport in red blood cells (OCR A Chapter 8.4) 

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me too

Opps! Typo error, thanks for pointing that out, well spotted! Thanks for watching :D

Hahahaha glad you found the video anyway!! Hope it'll help you next term after the summer break! :) Thanks for watching!

Yes, the concentrations of CO2, H+ and HCO3- within the red blood cells (RBC) will affect how much of this chloride shift occurs, but to put it in simpler terms... The point of chloride shift is to move the HCO3- ions out to the plasma, so to maintain the concentration gradient between RBC and the tissue fluid, to enable more CO2 to be converted into HCO3- form to be transported. The idea is to make it so as much CO2 can be transported away from the respiring tissues as possible. However to move the HCO3- ions out of the RBC and into the plasma, it requires a transport protein as charged ions normally cannot diffuse across the plasma membrane... And this transport protein is a cotransporter, meaning it'll only work if it also moves something in the opposite direction (kind of like the Na+/K+ pumps in active transport). And this "opposite" molecule is the chloride ions! In other words, in order for the transport protein to move HCO3- out, it also needs to move Cl- in, and vice versa. The exchange is on an one in, one out basis. Hope that makes sense? I hope that clears it up! And thanks for watching! :D

​@@BioRach Yes, I understand it as much as I probably need to at least! Thank you so much for such a thorough response :D

Absolutely! And this actually explains the Bohr shift on how the haemoglobin's affinity for oxygen changes depending on the carbon dioxide concentration in different tissues/organs! :D see my other video on the Bohr shift!

@@BioRach just came from the vid. Got a level year 1 exams coming up. I love uou

Yes will do! It's high on my list cuz loads of people have been requesting it :) thanks for watching!

Plasma is the liquid in blood. Tissue fluid is outside of blood vessels and surrounding the cells.

Thanks for watching! :)

@@BioRach love your approach to the topic ❤❤

Haha thank you!! :D

No I haven't. I am aiming to cover the whole spec but that does take time... Eventually I will have! For now, feel free to check out the other videos :)