Dude never stop making these, You're bettering the world. Please keep going with science stuff, It's the most important! us anatomy and biology majors need you!
dude i had absolutely no idea what my teacher was talking about and neither does my class u summed up her whole 1hr lecture in 13min and made it sooo much simpler THANK YOU!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
+Dearic Smiles right, ive been going to 3 hour biochem lectures for the last 8 weeks, and what the lecturer said in 3 hours, this guy has said in like 10 minutes
Dearic Smiles may be they didn't know it or didn't bother to tell you most teachers are dictionary of concept information only a few know what it really is.
Awesome work ! I think all biochemistry teachers should see these videos before they get out there to teaching. This is how explanation should be and not to confuse students or try to make the subject even harder.
Just a clarification: phosphate is not on the periodic table; phosphorus is and is the element that would have 5 valence electrons. Phosphate is a polyatomic group which is shown in the molecular structure in the video, so it was probably just a slip of the tongue as with the centrioles and centromeres in the mitosis video... :-P Thought it was worth clarifying for anyone confused though.
Can't thank you enough. My Human Biology Professor is from Nigeria and has a very thick accent and reading the book can only do so much! Khan, you are my hero!
I always look up youtube video's to explain the shit my Biology teacher couldn't explain in a week. This video was very useful. Thank you for sharing this with us. :)
your comment about taking it as a leap of faith really stuck me. I hated biochem for the main reason that i had to take everything in it as a leap of faith, and i didnt appreciate memorizing it. Thanks to your video i can finally understand it and not just memorize it and say it just happens. Thank you so so so much
It took mu chemistry teacher 2hrs to explain this n i still didnt understand it. U explained every thing he did n 15 minutes and more clearly. FCK paying 3grand a semester you tube you are my new teacher.
I had to watch this for a moodle day for my biology class (Moodle is a system that my school is privilidged to use, and we take a day off of school [about every 2 wednesday of the month] and do all of our work online, and I will say, this man can explain all of this better than any of my teachers ever could, and I will say, I think anytime I don't fully understand any concept that my teachers try to explain, I will come here.
I can tell this guy is trying to teach us "visually". Which is a great thing when he draws out, and explains everything. I would ace this dude's class if he was my teacher. :)
The electrons in ATP around the phosphate groups are being pulled in a bunch of different directions and are therefore in high energy states. When a bond between two P groups is hydrolyzed, the electrons in the P groups can drop down to lower energy levels (closer to the nucleus). When this happens, energy is released. The difference in energy levels results in release of energy.
"When the phosphate is broken by hydrolysis, it can transfer a considerable amount of energy." that came straight out of the textbook. im not saying your wrong but now im confused lol
thuglife6161971 the textbook is saying exactly what he said in order for atp (stores energy) to transfer into adp (used energy) you will need h20 as the middle man. Hydrolysis - the chemical breakdown due to the reaction with water. Hope that helps 💓
@Ben. This is a subject for a more advanced course, but creatine is like a "shuttle" or "valet parking" for high energy phosphate (ATP). It helps move energy from intracelleular stores to the mitochondria. Eating it doesn't really do much for you, aside from placebo, but the water comes into play in order to protect your kidneys (your natural body filters) from being hurt.
thank you, thank you, thank you!!! I am in Biology right now and for some reason cellular respiration was confusing the shit out of me, but you make it so easy to understand!
Thanks A lot! I always learn better visually and the concept of ATP was kind of looming over me because I got the rest of my material but this video helped ALOT! thanks for making it easy to understand ^^
Maan, really wished KhanAcademy was my teacher at school, all my current teacher mostly does is give us bookwork to do, then the day before the test, tell us the main points so we can cram.
Wow I knew most of the stuff at the start but approaching the end I learned a few intresting things. This is so fascinating because i started lifting weights when I was 16 and fell in love with the science behind it. Im 17 now and I have had amazing results in the gym and its intresting to know what is actually happening. the world is just amazing I get teased for watching this for fun but I dont even care lol way better then mtv and drugs my friends are all into
Just a clarification: The energy is not released when the bond is broken. From the perspective of physical chemistry, energy is released only when bonds are formed. In the case of ATP, simply cleaving ATP is actually an energy investment - energy is only gained when the third phosphate becomes attached to another molecule. As an example, the free P may causes changes to the shape of an enzyme, which, in attaining a more energetic form, may facilitate the otherwise hefty amino-tRNA synthesis.
WOW I have been looking for WHY and HOW does this break f 3rd Phosphate break off what breaks it off and why does it create energy... and here is the answer to number 1 how ie breaks off .... THANK YOU !!!!! I think I have spent a week looking for an answer and here it is... NOW can you show HOW IT IS THAT IT GIVES ENERGY ability to do ... what does it do,,, what does it maybe catalyze ???? ml bente
Energy is basically the ability to cause things to happen. In this case, ATP is storing energy in its chemical structure until it is required to fuel biological chemical reactions.
Enthalpy (bond energy) has little to do with the energy transfer capacity of ATP, or any other biomolecule for that matter. Energy in to break a bond! It its all about entropy. P-O bond rotation is restricted by the negative charges. Resonance is restricted in the phosphates. Popping the phosphate off removes those restrictions, with a resultant entropy gain.
so where does atp energy come from, is it mined, gathered, hunted, harvested? all the above? what is the effect upon mother earth when we play with these bioenergies and what about disposal? this only looks at the technical side of things and not about the effects. it may make us smarter in some ways but at what expense?
Could anyone please help me understand how the phosphorus in the ATP molecule is bonding to the oxygen? It makes absolutely no sense to me since P only has the ability to make 3 covalent bonds and it looks like its bonded about 5 times to oxygen.. are some of those bonds ionic? I mean I can see that some oxygen atoms have a negative charge but does that mean that it creates an ionic bond with phosphorus? But even then, wouldnt the fact that oxygen has an extra electron make it more electronegative meaning that it would be more likely to bond covalently? I'm extremely confused so if anyone could answer my question it'd be greatly appreciated.
Update: after doing a bit of research I found that what appears to be double bonds between the P and O are not really double bonds, it is just the phosphorus sharing its lone pair with oxygen to fill its valence shell but the oxygen does not share any of its electrons with the phosphorus atom. I am posting this just in case anyone has the same question as me at some point and hopefully to save you some time.
So, the phosphate groups store energy by making their electrons uncomfortable. Why is the adenosine necessary? Clearly there would have to be something there, so that other molecules could recognize it and the body could control it, but why adenosine in particular? The group would have to be consistent, since it is part of something intended to be a currency, but would it have to be adenosine? For example, could some alien biological system use something completely different?
Why does it have so much energy to give away? Is it because there is a lot (and takes a lot) of energy used by molecule to hold the negatively charged phosphates together and by breaking the bond there is a lot of energy released because new bonds formed are more stable and don't require as much energy?
Question; So adenosine triphosphate is composed of adenosine and 3 phosphate groups. & adenosone diphosphate is composed of adenosine and 2 phosphate group... & a hydroxyl group? Always?
@godsownphilosopher how is it that energy is released when bonds are formed? I can understand that it "costs" energy to cleave (good word, btw) a phosphate from its "comfortable configuration" (as a physicist, I might use the phrase "least potential state"), but it's hard for me to picture a release of energy upon bonding. What form does it take? Sorry for my lack of knowledge in physical chemistry :)
Could you use ATP for replacing fossil fuel by efficient (and hopefully simple) synthesis under room temperatures? I don't like all the storage problems H2 gives us. PS: This is no joke question.
