Guybrush singing to Van Helgin in the Barbery Coast was a highlight of the game. Also you can pick up a speaking LeChuck toy from the smuggler's cave on Skull Island. My personal favorite moment is when Guybrush gets revenge on the winch operator (before he leaves Skull Island with the Lost Welshman), but only if Guybrush fails to stop his free fall from the dead waiter earlier.