@@SiebertScience Hi there , i have a question , i heard of someone having B3 blood type what does it mean is it relevant in comparison to the + - Rh factor of the blood ... i could not find anything on it all over the internet and not even in a Medical physiology book
Thank you, thank you, thank you! Makes perfect sense. You are my go to for my Anatomy class. I learn best by watching videos and I come to your channel every time!
Really you are the best, I wouldn’t understand anything without your videos. You make it very easy for me to receive the information. All your videos are very helpful thanks so much, and I wish you were my professor 😂
I have an idea for a new video for you. Do a video on the rare blood type, cis-AB. This blood type which is the result a rare mutation is generally the same as a normal AB blood type in regards to the transfusion compatibilities etc, The difference in the cis-AB blood type from a normal AB type is in how it's constructed. Normal AB blood types as you know, inherit an A allele from one parent and a B allele from the other parent. But one of the two alleles in the cis-AB type person is an AB allele all its own. (Both the A & B versions of a blood type gene are found on one Allele). So, a person who has this blood type possess one allele being AB and the other allele being any of the other normal ABO types. This mutated cis-AB allele will dominate the other allele type no matter what type it is, resulting in the person always presenting as having AB type blood. One unique thing about a cis-AB person is that if for example, the genotype version combination of that person is the cis-AB allele and an O allele, that person could actually possibly parent a type O child if the other parent also possessed an O allele, which is something that would be impossible with a normal AB phenotype because a normal type AB person only has an A allele and a B allele to work with. The cis-AB blood type is very, very rare around the world, but is mostly found in the Korean and Japanese populations, But even in those populations it reaches a frequency of only 0.035% in Korea and 0.0012% in Japan.
How can I determine if I have Cis-AB ? I was told I am AB- and my child is o+ . Recently my child was confirmed that he is O+. My question is also that proving maternity with Cis-AB is easier than if you had chimerism ( which is way different than a mutation). I also have health issues so I want to make sure my blood group/type is correct so if anything, I won't be giving the wrong blood if needed.
Excellent explanation of blood types and the most commo antigens, it would be great if you make a video about indirect coombs and direct coombs, regards from Venezuela
thank you for making these videos. I fall asleep reading the textbook. I'm currently watching all the systems by you and I like how you make it fun by saying the adrenal glands are like party hats for the kidney lol. Yes I'm on your endocrine system video! keep doing what your doing and thank you for teaching me in a nonboring way. Your system is clear and I appreciate the pictures and drawings your the best !
Thank you infinity ❤️your way of explaining exactly how I learn , I Cant learn much from class , but with drawing and explaining making it super useful. I hope I discover your channel sooner
you are great like all the time! One question left in my mind: When we give O+ blod to a person with A or B+. The O does not have antigen but it has anti bodies. Does´nt O antibodies affect the anti gen of the blod A or B?
Why does the a antigen in blood type A not react with the a antibody in blood type O when donated to Blood type A? I think I missed something, someone pls help
You are an amazing Thank you so much for this video .but can u please speak a little bit slower some foreign people watching you video and we can catch all your words
Hello! That’s a great question that you should ask your doctor. I’m just a guy who makes RU-vid videos…I’m definitely not qualified to give medical advice. I hope everything goes well for you and the pregnancy though!
who can donate to a patient who is a+ that has antibodies that attack bloodcells that they dont recongnize ? ex if i have a anursym (which i do ) how will this anibody in my blood react to a blood transfusion if i need a transfusion ? is there a specific type blood i have to recieve ? what do i need to know incase of a blood need on my end , if i need blood
assuming the "antibodies that attack bloodcells that they dont recongnize" aren't targeting a protien not talked about here, you have A and Rh(+) antigens which means you only have B antibodies, so any blood that isn't type B will be accepted.
I really appreciate this video, it was easy to understand and very informative. Now I know that because my blood type is A-, I cannot receive blood from my brother, whose blood type is O+. Could you make a video on how the Rh factor affects pregnancy?
I probably misunderstood your explanation about the O blood type. It has no antigens A or B, but it has both antibodies A and B. So, if this type of blood is donated to say A which has A antigens and B antibodies, wouldn't the A antibodies contained in the O cause a reaction with the A antigens?
I have couple questions: 1) is it known why do we have different blood types? why nature doesn't have just one universal type? 2) if O blood is donated to A blood, does O receive A's antigens and transform into A blood type? If yes, is it applied to all blood types? 3) if my blood is donated to another person, will he receive my DNA that comes along with the cell?
,,,,question 1....it's just a genetic possibility based on regional genetic development...the same with hair, eye and skin colours. Nothing special. It's said that group AB is a comparatively recent development based on interaction between Mongolian and central European populations. Question 2...it just merges with the existing blood in the body and there are no adverse reactions as long as there is no possibility of conflicting antigens and antibodies. See it as the same as pouring water in a leaking bath...there are only issues if the water has bleach in it at which point the bath water becomes toxic. Question 3...yes, but it will not excite your antibodies to attack it. Blood refreshes itself quite quickly and there will be no adverse reactions as the new, specific genetic code will soon be merged and then replaced. Water can be introduced into the blood stream to aid hydration as can glucose and sodium etc. and it's doesn't get attacked, either...
Dear sir, I have a question, According to the explanation, When donor's blood group is 100%same as the receiver's blood group, then you don't have to extract the plasma from donor's blood sample. But imagine, If donor's Blood group is A, and the receiver's blood group is AB, then you must extract the donor's blood plasma and remove it. because, donor's blood plasma contains B antibodies and they can react with the receiver's Blood Cells. Am I right ?
I have a question, I was told I have O+ Blood, but when my blood was looked at I was told I also lack an entire group of antibodies, and that my doctor had never seen that before. Do you know what this could mean? I have been confused ever since as to if something is wrong with me or not and if this would cause problems if I ever needed a blood transfusion. I already know O types don’t have antigens, but what does me missing a whole antibody group as well mean?
you said we _can_ remove the plasma when giving a transfusion, let's say when donating O to A or B, is it always necessary to do so? I always thought you can just take blood and donate it without altering it in any way 🤔 but according to this it would be dangerous right
I'm O negative, but because I was in England in the 1990s during their mad cow outbreak, I have been told I can no longer donate blood. How does that work?
@@SiebertScience I'm much obliged. The good news is that I've got the full mark! But I feel a bit ashamed because I don't have the full picture of what's happening, like what are antigens and antibodies, what're their chemical structure and main function. But I'm still on the beginning; I have lots of time to learn it all. But thank you so much for opening this door to me! I just noticed that I'm sending this message from my second account, but I'm Flying Feather btw.
Technically, all official websites and sources I've seen regarding the antibodies, refer to them as "anti-A" and "anti-B" antibodies. Not "A-antibodies " or B-antibodies". I've only seen letter prefixes used for antigens. "A-antigens" and "B-antigens". But I digress. We get the idea. But it could be confusing to some some people. Regardless, nicely done video! Also, good job talking about the removal of plasma before transfusion of red blood cells. Most videos don't even mention that and I see a lot of comments expressing confusion and asking how can a O blood type be given to the A, B and AB types if it contains the antibodies for all those antigens?. So, great job explaining that!
