Thank you Doctor Campbell, I found your videos because I am researching why I have been so poorly for 8yrs. I have a cluster of kidney stones one being 16mm in size and stuck in the left kidney. I wanted to find an understanding on how the kidney works, I have just read about the three main functions, so I wanted to know about water retention. All very interesting and I wonder why my GP only wants to calm a symptom rather than heal the cause. Which is why I am doing my own research. I will find a cure to heal my kidneys. Granted I can't cure a 16 mm kidney stone but with knowledge I can prevent the list of symptoms. Many thanks for your time producing your training videos.
Love you Dr. John Campbell. Only Love and kisses. You are so knowledgeable and there is a sense of calmness in your voice that I just cannot resist not to listen to you for one day.
There are a lot of videos about water regulation by hypothalamus (obviously it includes pituitary) but most of the videos provide either wrong informations or incomplete information. But, your video makes me all cleared about water regulation by hypothalamus as well as pituitary. Thanks a lot SIR.. Thanks from INDIA. I know that my English is not good but if there is any mistake in my writing please forgive me. Thanks again. Sir l Love You❤️❤️❤️❤️❤️🙏🙏
Holy carp this was complicated to figure out, I think chatgpt was also confused by the literature. So the way I finally understand fluid balance this is how it works: For proper sodium blood levels, you actually need both the kidney (aldosterone) and hypothalamus (anti diuretic hormone). The sodium concentration sensors in the kidney will result in increased aldosterone in hyponatremia. But, that alone is not enough. The aldo increases sodium reabsorbtion. That had me spin forever because in reality it only increases fluid reabsorption, period. Ie all the fluid, with salt. Which makes sense because the main purpose of aldo is to increase blood pressure, triggered by pressure receptors. Anyhow, so now we increased fluid retention, including salt, but what the kidney wanted was higher salt, not higher fluid, so what gives? The hypothalamus osmolarity sensors also sense low salt, or osmolarity, so they reduce release of ADH. Adh, also sending me for a spin, increases water absorption, but that’s without the salt (go figure). So in effect, it is the one that increases salt concentration, by reducing ADH, and filtering out more (pure) water. The liver can also be a cause of fluid problems when it produces too little albumin, which distorts osmolarity and sodium. NSAIDS can reduce ADH effect and basically screw with every other fluid regulating mechanism, leading to edema or worse. SSRIs may cause hyponatremia via increasing ADH.
Hi Doctor Campbell, You probably don't read these comments on old post but just in case. I have a question, have you ever reviewed studies the use of reverse osmosis water systems. I read something recently saying they are terrible for you health because they take out all the minerals from the water and that you can't add it back in the way unfiltered tap water does. Just wondering if this is detrimental to health or if you've ever looked into this. Thank you of you read this😊
sir, could you please explain to me what is osmotic pressure but in a verrrrrrry simple terms? i have searched all over the internet but i haven't quite grasped the idea please help me understand this
