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Bone remodeling and repair 

Osmosis from Elsevier
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What is bone remodeling and repair? Bone remodeling is when old, brittle bone tissue is removed or resorbed and gets replaced by new bone tissue. Remodeling also occurs when reshaping your bones after a fracture or when repairing micro-cracks which form during ordinary activities, especially when your bones are under stress, like after lifting heavy weights. Find our full video library only on Osmosis: osms.it/more.
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13 окт 2020

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Комментарии : 173   
@alfathrahagika7226
@alfathrahagika7226 3 года назад
why this gave me more understanding than my college..i love it
@kashifkhan7379
@kashifkhan7379 3 года назад
Focused on lecture rather than Girls 😂😂😁
@This_or_Thatx1
@This_or_Thatx1 2 года назад
Willl my bone density will grow after quitting drugs? I am 23+.
@amnafayyaz6768
@amnafayyaz6768 Год назад
Because you are fool 🤣
@bayannasseral-harrasi6089
@bayannasseral-harrasi6089 Год назад
Bone remodeling in short: -Osteoblast release M-CSF & RANKL → Convert monocytes into osteoclasts → ↓ Bone mass -Osteoblast also release Osteoprotegerin (OPG) → OPG will inhibit RANKL → ↑ Bone mass
@senankavanagh2382
@senankavanagh2382 3 года назад
Great video. ties everything together nicely. Decided to review bony remodelling today and fascinating what you can pick up again on revision. Initially when learning about bony remodelling I never really thought about the significance of RANKL , but with drugs such as Prolia , a RANKL inhibitor , it becomes obvious as to why the fundamental understanding of the physiological processes is vital to clinical practice with associated pathological states such as Medication related oseteonecrosis of the jaws. Many thanks.
@uhlezza
@uhlezza 3 года назад
This was really helpful plus the illustrations are adorable!! Thank you so much.
@rasheshdas
@rasheshdas 3 года назад
The illustrations are fabulous
@user-rk7ox1pb6x
@user-rk7ox1pb6x Год назад
Finally understood the mechanism after 5 retake. love this type of resource, really insightful and articulate.
@osmosis
@osmosis Год назад
We're glad it helped, Dhruv! 🙏🏼
@evakhwaiss7484
@evakhwaiss7484 3 года назад
I've searched more than 1 hour for a video like this, thank you so much 😍 this sums up everything i want about bone tissue 👏
@osmosis
@osmosis 3 года назад
Hi Eva, Glad it was helpful!
@abel6298
@abel6298 5 месяцев назад
Read your bible! (KJV, preferably) ♥‎
@sarahesse2979
@sarahesse2979 6 месяцев назад
Thank you for sharing. Please we would love to see more videos like this
@degodaniyt6557
@degodaniyt6557 2 года назад
I would have loved to see more infromation about hormones and their influence on bone remodelling, such as the osteolytic effect of cortisol and such. An all-in-one video of what hormones affect bone remodelling.
@MA-fd6kg
@MA-fd6kg 3 года назад
Great video! Helped me a lot!
@DrDY-us4rg
@DrDY-us4rg 3 года назад
That was exactly what was needed
@LuanTran
@LuanTran 3 года назад
What a vivid way to present such hard topic. Thanks a lot !
@osmosis
@osmosis 3 года назад
Thanks for your wonderful comment! 🥰
@laurenndance
@laurenndance 3 года назад
Pretty helpful! Thanks!
@mikhailkushadiwijaya1027
@mikhailkushadiwijaya1027 3 года назад
Simple yet deep and well explained. Thanks a lot. Please make more animationlike this. I really appreciate it. Gbu all team!
@osmosis
@osmosis 3 года назад
Thank you Mikhail for that wonderful feedback!
@maymansourian7417
@maymansourian7417 2 года назад
Another great video by the Osmosis Team! Thank you!
@osmosis
@osmosis 2 года назад
Thank you too! 🙏🏼
@paltrygorilla9151
@paltrygorilla9151 3 года назад
Thanks Bro! this really helped me.
@heathenwizard
@heathenwizard 3 года назад
Great visuals and wonderfully concise and explanatory! Thanks so much!
@osmosis
@osmosis 3 года назад
You're very welcome! Thanks for letting us know!
@melindaaa1404
@melindaaa1404 2 года назад
This is the perfect video for this subject. Thank you so much!
@osmosis
@osmosis 2 года назад
Glad you think so!
@MinhNguyen-li2eb
@MinhNguyen-li2eb 2 года назад
Amazing. Now i remmeber the core of a complicated process in our body. TKs a lot
@osmosis
@osmosis 2 года назад
Glad to hear that, Minh! ❤️
@mshaik435
@mshaik435 3 года назад
Osmosis makes med school easy♥️love this channel. So accessible
@osmosis
@osmosis 3 года назад
Yey! We're glad to be of help to your medical journey! If have time, feel free to sign up for a free trial at osmosis.org so you can access more of our video library and other study features. 😊
@charmimgshahnaz7455
@charmimgshahnaz7455 3 года назад
Dear Osmosa,,, please make a video about closed fracture.. thanks a lot.
@foramsanghavi9328
@foramsanghavi9328 2 года назад
That's wonderfully explained..Made understanding very clear just in 5 min.. Thank you so much
@osmosis
@osmosis 2 года назад
Glad it was helpful, Foram! ❤️
@Realmadridforever714
@Realmadridforever714 3 года назад
One of the best video on bone remodeling
@osmosis
@osmosis 3 года назад
Wow, thanks for that feedback!
@khushishah2130
@khushishah2130 3 года назад
❤️❤️.. plz make a video on osteoporosis
@ayamohammed7753
@ayamohammed7753 Год назад
Great explanation ma sha Allah!
@katharina6865
@katharina6865 2 года назад
Wow, this is really informative. Thank you! I lost 2 Parathyroids after a messed-up operation. Still don`t know how to deal with this, but trying and learning. 😰
@osmosis
@osmosis 2 года назад
Sorry to hear that. Katharina. We hope you're doing better now. 🙏🏼
@kuengatshomo7396
@kuengatshomo7396 9 месяцев назад
Wow thats so helpful...Thanks alot. In the midst of confusion and infodemic, its like a hopeful rays.
@osmosis
@osmosis 9 месяцев назад
Glad it was helpful! 💫 🥰 💖
@lynnlive21
@lynnlive21 3 года назад
Thank u! ♡
@Chuckbgd
@Chuckbgd 3 года назад
thx! it help me a lot
@arshishamim4064
@arshishamim4064 3 года назад
nicely explained :)
@alikadhim4546
@alikadhim4546 3 года назад
Amazing ♥️♥️♥️♥️ thank you very much
@fevenre4969
@fevenre4969 3 года назад
Very brief vidio......Thanks alot
@wendyfer735
@wendyfer735 2 года назад
Thank you!
@nothing_fancy692
@nothing_fancy692 2 месяца назад
Thank you!!! It makes so much sense now!
@osmosis
@osmosis 2 месяца назад
Glad to help! 😊
@marysakala1079
@marysakala1079 2 года назад
Very clear and straight forward
@osmosis
@osmosis 2 года назад
Thanks, Mary! 👍🏼
@cpbeauvoir
@cpbeauvoir 3 месяца назад
Watching this on my way to my test. Thank you
@osmosis
@osmosis 3 месяца назад
We hope it went well! 🙏🏼
@rasheshdas
@rasheshdas 3 года назад
Thank you very much
@ramokunupisekgwaila5033
@ramokunupisekgwaila5033 2 года назад
Well explained 👏👏👏, thank you so much 🙏
@osmosis
@osmosis 2 года назад
Glad you think so, Ramokunupi! 🥰❤️🙏🏼
@melinaguillon2449
@melinaguillon2449 5 месяцев назад
Amazing content and animation! Thank you!
@osmosis
@osmosis 5 месяцев назад
Most welcome, Melina! 😊
@navyashreedegowl9352
@navyashreedegowl9352 3 года назад
U ppl.arw.doing such a great teaching ..thanks a lottt
@osmosis
@osmosis 3 года назад
Hi Navyashree, thank you, we're glad you find our videos useful! :)
@rethijja3331
@rethijja3331 2 года назад
This is amazing
@Vikrant-7812
@Vikrant-7812 11 месяцев назад
I'm gonna send this video to my professor 💀✌️
@alkynesofatoms9315
@alkynesofatoms9315 8 месяцев назад
Great, thank you.
@CHRISGURJAR
@CHRISGURJAR 2 года назад
Awesome explanation. Loved it.
@osmosis
@osmosis 2 года назад
Thanks, Chris! 😊
@nihalgaber3403
@nihalgaber3403 2 года назад
I have a question please regarding Wolff's Law: if we say that Applied pressure results in bone resorption, while applied tension results in bone formation. is that correct or not?
@requestcontrol1886
@requestcontrol1886 3 года назад
God bless you people
@itxmfahadkhan
@itxmfahadkhan Год назад
You are a life saver ❤️
@osmosis
@osmosis Год назад
Always glad to help, Muhammad! 🥰
@ADAPTATION7
@ADAPTATION7 2 года назад
Parathyroid gland stimulates osteoclasts (not osteoblasts) for bone resorption to occur. Small mistake at 5:05.
@ruveydalipa
@ruveydalipa Месяц назад
This is so good but i dont know english well so it was hard to understand😭😭 but tysm anyways that helped a lot🥹🫶
@halobium3513
@halobium3513 2 года назад
excuse me but do you have a video explaining mechanism of healing of bone's fracture?
@jayarramos2300
@jayarramos2300 3 года назад
How about left humerus? How many months it takes before healing?
@sufias1459
@sufias1459 2 года назад
Perfect👌Tnks✨🌸
@sitiulfaturrizqa3555
@sitiulfaturrizqa3555 2 года назад
woow I love this one, thank for amazing video :)))
@osmosis
@osmosis 2 года назад
Glad you like it, Siti! 🙌🏼
@mardenidres
@mardenidres 3 года назад
Really hepful thank you so much 💜
@osmosis
@osmosis 3 года назад
Our pleasure! 😊
@mahuubao
@mahuubao Год назад
Excellent ... well done ...
@osmosis
@osmosis Год назад
Thank you, Mahu! 🙏🏼
@azouz5675
@azouz5675 3 года назад
why there is resorption in one side and the deposition in the other side not in the same side ?
@munishgupta2226
@munishgupta2226 2 года назад
Excellent presentation , but as far as I know osteoclasts doesn't produce COLLAGENASE , it is produced by osteoblasts actually , bone resorption by osteoclasts at it's clear zone (at ruffled borders) mediated by carbonic anhydrase , secondly it pump out hydrogen ions( after CO2 hydartion - H2CO3 formation - breakdown into Hydrogen and carbonate ions -then pump out hydrogen ions) which lowers pH , lysis of collagen in acidic media , which leads to bone resorption , Plz tell me if I m wrong
@maja0247
@maja0247 7 месяцев назад
Thank you so much this is amazing
@osmosis
@osmosis 7 месяцев назад
You're so welcome! 💖
@dunyaimanova9207
@dunyaimanova9207 Год назад
the best explanation 😍
@osmosis
@osmosis Год назад
Thanks, Dunya! 💕
@wifaqjaborialbazy-4405
@wifaqjaborialbazy-4405 Год назад
excellent job
@osmosis
@osmosis Год назад
Many thanks! ❤️
@ranch-ng1gv
@ranch-ng1gv Год назад
I wish my actual lecture was that easy with less deatails :(
@eugenunesdemoraes2398
@eugenunesdemoraes2398 Год назад
Great video, thank you
@osmosis
@osmosis Год назад
You're welcome, Euge! 🥰
@thomasbays8292
@thomasbays8292 Год назад
My daughter had PAO surgery. The coverage is good no doubt. She still has pain and is very thin, could bone remodeling be an issue?
@rosiefans863
@rosiefans863 8 месяцев назад
Understand thanks. A lot
@osmosis
@osmosis 8 месяцев назад
Happy to help 🙏🏼
@Omar_11234
@Omar_11234 3 года назад
amazing❤❤❤❤❤❤❤❤❤
@dr_blueman
@dr_blueman 7 месяцев назад
Thank you. ❤
@osmosis
@osmosis 7 месяцев назад
You're welcome 😊
@HAA-wasteAcc
@HAA-wasteAcc 2 года назад
holy shit that's so good
@gauravgupta174
@gauravgupta174 2 года назад
When the bone is getting remodeled due to stress fracture , does it add 2-3 inches in height growth . When fully recovered
@francesca186
@francesca186 11 месяцев назад
hi, could you add the bibliography used to make this video? it was so useful to me and i'd like to read sources too
@osmosis
@osmosis 11 месяцев назад
Hi Francesca! You may access this information when you hop on osmosis.org! Please feel free to sign up for the 7-day free trial (no card needed) anytime 😊
@GuidetteExpert
@GuidetteExpert 2 месяца назад
Are these cytokines that these cells use to signl or use as a communication to start og stop a process?
@mike.m4621
@mike.m4621 3 года назад
I had 12 years ago a femure fracture very ugly caused by a tumore. I had surgery ofcourse the doctor said he clean everything there very good and he put me a metal plate wich I still have now and than I had the chimioterapy treatment. After 3 years I started to go slowly to gym and workout slowly but still even now after years I still cannot do the exercises for legs I did before the fracture because some pain during workout. You think the femur after this damage has healed properly? I will like your opinion also. Thank you
@Kiran.2020
@Kiran.2020 2 года назад
You are the best ❤️
@osmosis
@osmosis 2 года назад
Aww.. thank you Kiaan! ❤️
@maryambukhari7635
@maryambukhari7635 2 года назад
Amaaaaazing !!!!
@osmosis
@osmosis 2 года назад
🙌🏼 💕 ✨
@btsismybias8332
@btsismybias8332 Год назад
Thanks a lot !!!
@osmosis
@osmosis Год назад
We hope our video helped! 🥰
@BhaskarDrukGiri0688
@BhaskarDrukGiri0688 8 месяцев назад
Awesome
@mehsudmedicos8768
@mehsudmedicos8768 2 года назад
very appreciable
@osmosis
@osmosis 2 года назад
Thanks!
@arh1511
@arh1511 3 года назад
Great
@EkilRevolution
@EkilRevolution 2 года назад
What do you think about bonesmashing?
@aventadorgamer1575
@aventadorgamer1575 3 года назад
Medical college life is easier with osmosis! 💗💗
@osmosis
@osmosis 3 года назад
Glad to be of help! 😊
@hananmohamed9302
@hananmohamed9302 Год назад
great vid
@osmosis
@osmosis Год назад
Thanks, Hanan! 😊
@KhadigalMohamed
@KhadigalMohamed 6 месяцев назад
Great ❤❤❤❤❤🥳🥳
@1cloudshinobi
@1cloudshinobi 2 месяца назад
What is the duration of this process
@hmzzrg5045
@hmzzrg5045 Год назад
I think there is a mistake at 2:41. Myeloid progenitor cells come from hematopoietic stem cells, not lymphoid stem cells.
@osmosis
@osmosis Год назад
Thanks for pointing this out! Our team will be reviewing this information and update the video as needed. 🙏🏻
@crenapun57
@crenapun57 3 года назад
Tq
@llostudio4278
@llostudio4278 2 года назад
Really nice
@osmosis
@osmosis 2 года назад
Thank you! 🥰❤️🙏🏼
@lukeskywalkerjediknight2125
@lukeskywalkerjediknight2125 3 года назад
Monocytes looks like a friendly thing 😊
@wypy817
@wypy817 3 года назад
Monocytes are the most badass myeloid cells
@user-xp3cg6dz4h
@user-xp3cg6dz4h 4 месяца назад
This is nice
@arizarichie9446
@arizarichie9446 Год назад
how long is it ? how long the process go ?
@wypy817
@wypy817 3 года назад
I just failed my exam because i never prepare for ortho sub the intro was so boring in my university lecture i need to start with this ✊🏻🤞🏻 wish me luck everyone i m gonna start studying this video give me so much hope i find it it very interesting and its very easy to understand this😁
@osmosis
@osmosis 3 года назад
Hi Pitchet! You can rock this exam! If you can, you may sign up for a free trial at osmosis.org so you can access our entire video library and study resources to help you ace your exam. This might help! We won't be asking for your bank details or anything, so no worries. 😊
@joewichterman1193
@joewichterman1193 2 года назад
My stupid bio teacher is making me learn this for a presentation tomorrow. Great vid if you have any clue what the stuff in it is. Does she think I’m majoring in orthopedics or something. No I’m just trying to understand transcription factors and how they affect bones. I’m screwed
@UHFStation1
@UHFStation1 Год назад
This didn't really explain how the bones know what shape they're supposed to be. I am particularly interested to know why spinal stenosis doesn't reverse itself relieving pressure on the spinal cord.
@grant4360
@grant4360 Год назад
I think there is a small mistake, yellow bone marrow does not produce blood cells as was indicated in the video. That is actually red bone marrow typically found in the epiphysis
@osmosis
@osmosis Год назад
Thank you so much for bringing this to our attention, Grant! I will be sure to pass this along to my colleagues on the Content Team so they can check the details with our Chief Medical Officer. 😊
@vijayramaraju3522
@vijayramaraju3522 2 года назад
Hello Sir, i had an small accident and 5th metacarpal was fractured, and it's just in position, doctor said, no need for k-wire , just split is enough for 6weeks. 2weeks back split is removed, now 2months completed, but fracture line still visible, how long it will take to go off fractured line on x-ray, and I'm afraid of do physiotherapy, because when I'm doing physiotherapy some pain on fracture site. Give me some suggestions, please, thanks in advance....
@mahmudulhaq564
@mahmudulhaq564 Год назад
Amazing !!!! I was struggling with this topic in Harrison Internal Medicine...you made it a cakewalk. PS- 9 days to go for my DNB Medicine finals😢
@osmosis
@osmosis Год назад
Best of luck, Mahmudul! You got this! 🤓🩺 🙌🏼
@honeybadger1621
@honeybadger1621 2 года назад
what if person diabetic? how will heal
@swagMan253
@swagMan253 3 года назад
Does this process take place in the skull bones like the jaw or cheekbones?
@karenk3986
@karenk3986 3 года назад
Good question
@Bassman7608
@Bassman7608 2 года назад
@5:03 I think you’re mistaken. Shouldn’t the osteoclast be reabsorbing bone to release calcium in the bone?
@osmosis
@osmosis 2 года назад
Hi Kevin! Thanks for pointing this out. We've notified our team about this so they can have the information reviewed. 😊
@StiffAftermath
@StiffAftermath 2 года назад
So...is bone death reversible?
@panda-pw6eg
@panda-pw6eg Год назад
Nice
@osmosis
@osmosis Год назад
Thanks! 😊
@mariamriaz2311
@mariamriaz2311 Год назад
Where's repair???
@peednas711
@peednas711 11 дней назад
It starts at 4:20
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