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Brain health, hormones & genetics with Sara (Gottfried) Szal MD & Dr. Yael Joffe 

3X4 Genetics
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Brain health, hormones & genetics - a webinar hosted by Dr. Yael Joffe and Sara (Gottfried) Szal MD, focusing on the intersections of genetics, hormones, brain health, and autoimmune disease. The webinar emphasizes how genetics can serve as a powerful tool for understanding and improving personal health.
Sara (Gottfried) Szal MD, a Harvard-educated physician, global keynote speaker, and bestselling author, shares her expertise in hormonal health, cognitive decline, and autoimmune disease management. She highlights the role of personalized medicine through genetics and biomarkers. Key discussions include the use of bioidentical hormones to manage age-related hormonal imbalances, the genetic pathways involved in hormone metabolism, and the increasing prevalence of autoimmune diseases.
Dr. Szal emphasizes the significant impact of trauma on health outcomes, particularly in relation to autoimmune conditions and epigenetic changes.
The conversation covers practical advice on using genetic testing to optimize health outcomes, understanding the importance of hormone testing in both men and women, and addressing how trauma and lifestyle factors influence gene expression. Dr. Szal shares her personal experiences and clinical insights, inspiring individuals to take control of their health by leveraging genetic insights and making informed decisions about hormone therapy and lifestyle interventions.
Key Talking Points
1. Introduction and Host/Guest Overview
- Hosts Dr. Yael Joffe and guest Sara (Gottfried) Szal MD, introduce the topics of hormones, brain health, and autoimmune disease.
- Overview of Dr. Szal’s background in hormones, precision medicine, and genetics.
2. Hormone Management and Bioidentical Hormones
- Discussion on the importance of managing hormones as we age and the shift in medical opinion regarding hormone therapy.
- Differences between synthetic hormone replacement therapy (HRT) and bioidentical hormones.
- Addressing common fears around hormone therapy, including breast cancer risks.
3. Genetics and Hormone Metabolism
- How genetics influence hormone metabolism, such as estrogen pathways that may increase or decrease cancer risks.
- Using genetic insights to personalize hormone management and optimize individual health outcomes.
4. Brain Health and Cognitive Decline
- Exploring the genetic and hormonal factors contributing to cognitive decline, including the role of estrogen in maintaining brain health.
- The importance of early intervention to prevent cognitive issues like Alzheimer’s disease.
5. Autoimmune Disease and Genetic Factors
- The rising rates of autoimmune diseases and the roles of genetics, gut health, and trauma triggers.
- Understanding the three factors required for developing autoimmune disease: genetics, leaky gut, and environmental triggers.
6. Epigenetics and Trauma’s Impact on Health
- How environmental and lifestyle factors, such as trauma and isolation, affect gene expression (epigenetics).
- The importance of addressing trauma to prevent chronic diseases like autoimmune conditions.
7. Personalized Medicine and Genetic Testing
- Practical applications of genetic testing in clinical practice, including hormone pathways, inflammation, and detoxification pathways.
- How 3X4 Genetics uses pathway-based genetic testing to provide actionable insights for personalized health strategies.
8. Practical Solutions for Health Optimization
- Recommendations on lifestyle changes to improve sleep, reduce anxiety, and enhance overall well-being.
- Encouragement for patients to advocate for hormone testing and personalized care, especially for those with unexplained symptoms.
9. Closing Remarks
- Dr. Szal emphasizes the empowerment of understanding one’s genetic blueprint to optimize health and reduce the risk of chronic diseases.
- Final thoughts on how knowledge can empower individuals to take control of their health and implement preventative strategies.

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28 сен 2024

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Комментарии : 1   
@lindadupuis1531
@lindadupuis1531 День назад
I am 66 yrs old in less than a month and have been suffering with many issues since perimenopause. I have resistant hypertension, had PSVT and had ablation therapy and had chronic UTI’s during perimenopause. It was a crazy time. I am still dealing with neurological decline, anxiety and sleep issues. I removed caffeine recently and drink decaf coffee and teas but still have very disrupted sleep. Cognitive decline has been evident since perimenopause as well as ADD symptoms. Is it too late to spend oodles of dollars to see a natural hormone replacement therapist? It’s very expensive in Canada to have anything holistic done. I did try progesterone cream years ago to find myself walking into walls etc. it was a horrible experience. Thanks for this great video. 🙏🏻 PS Dr. Sara I did your Hormone Reset program and had good results.
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