#calcium#interpretyourbloodtests
Disclaimer:
IYBT is not a substitute for your Doctor consultation. Blood work only acts as a supportive workup to your physical examination and always needs to correlated by a professional doctor before taking any step in the management. Hence, seeking the advice of a professional doctor in the related field is adviced for questions related to you symptoms , diagnosis and management.
If you have or suspect that you have a medical problem or condition, please contact a qualified health care professional immediately. You should never disregard or post pone the medical advice given by your doctor just because you have seen or read the content in the channel
Calcium forms the basic structural component of bones in the form of calcium hydroxyapetite. Major function of calcium inlude cellular signalling, neuronal transmission, contraction of soft and skeletal muscles.
Only 1 percent of the calcium is present in the circulation. Of that around 50 percent is free while the rest is bound to albumin and organic anions . The part of the calcium which is free is called as ionized calcium . It is the active form of calcium.
Reference range of
Ionised calcium : 4.6 to 5.8 mg/dL (1.15 and 1.30 mmol/L)
Total Calcium : 8.5 to 10.5 mg/dL
Normally total calcium reflects the amount of ionized calcium hence testing of ionized calcium is not routinely required unless in special conditions involving parathyroid disorders.
Corrected calcium (mg/dL) = measured total calcium (mg/dL) + 0.8 (4 - serum Alb g/dL)
Corrected calcium is an estimate of the total calcium concentration, had serum protein (albumin) concentration been normal. Although "corrected" total calcium reflects ionized calcium more accurately than uncorrected total calcium in patients with abnormal serum protein concentration, none of the correction formulae are entirely reliable for all patients.
The two principal clinical situations in which total calcium concentration does not sufficiently accurately reflect ionized calcium activity are:
1.Those in which the patient's serum protein concentration is abnormal
2.Those in which the patient is suffering disturbance of the acid-base balance
More info :
www.interpretyourbloodtests.com
Follow us at : / interpretyourbloodtests
22 авг 2024
