The evidence behind collagen supplements still isn’t very solid, but it’s a myth that it’s scientifically impossible! More about collagen supplements here: • Do Collagen Supplement...
The evidence behind collagen supplements still isn’t very solid, but it shouldn’t be dismissed as scientifically impossible! More about collagen supplements here: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE--6HLBuELGD0.html
@@user-mi5xq8zj7u for one thing, seed oils do not moisturize. They just hold in the moisture that's already in your skin. And can cause melia and they clog pores and can either cause or aggravate acne. They are also contraindicated for most cases of rosacea. Your skin usually produces all the oil that you need. And some seed oils are irritating.
Hi yes I graduate as a pharmacist this coming May. Natural/herbal/dietary supplements have this unfortunate issue where they aren't regulated in the same way that OTC or Prescription medications are. While that might sound fine at first, what it ends up meaning is anybody can put anything on the shelf to sell, and we have to prove its bad to remove it (whereas for OTCs you have to prove its good first before it even gets put on the shelf). TLDR even if a supplement ingredient can have its desired effects, you HAVE to find a good product (appropriate amount of the substance, good manufacturing practices, etc, none of which are required for them to be sold)
Related note: if they decide they are using a "proprietary blend" of ingredients, they don't have to tell you how much of each is in the product, and are only required to list them in order of most to least in the product.
Hi Michelle I do take a collagen supplement, but I have noted it seems to make my hair and especially my nails grow faster - not really visible skin benefits seen however. I also feel it helps my arthritic joints a bit and truthfully that's my main reason for taking it. I do have protein in my diet everyday, but maybe it's just boosting that - who knows? In any case when I stop taking it my hair and nails aren't as healthy and my joints ache more. I don't think it's a placebo effect, as the difference is visible - seen first in my nails. I don't use a massively expensive brand and am happy enough with the results to keep going with it. I think the claims out weigh the actual benefits (not unusual lol) and all supplements should be considered carefully before being introduced (in consultation with your Doctor). Best wishes.
Collagen & keratin do have some overlapping amino acid building blocks. Eg proline, though it's not an essential AA, and you can find it in lots of other foods (including cabbage, surprisingly. Now there's a super food! And it's only 99¢/lb!).
I’ve been on a Collagen video binge watch for the past few days, and I thought yours was great! It seems like there are a lot more studies out nowadays, would you ever come back to the topic?
I started using a product containing Verisol collagen about 4-6 weeks ago and my fingernails have grown like crazy! It’s the longest I’ve ever seen them grow before breaking. I’ve used other collagen powders before and didn’t notice this…only with the Verisol type of collagen.
This is nice to know. I’ve started taking it recently as post pregnancies I have horrible pain in my feet, hands, hips, and knees. I’m hoping for some relief. If it helps with wrinkles that’s a plus as I don’t get very much sleep with these energetic children.
can i just say i love your channel. you keep your biases aside and even admit where you have them you show your work and inform on a base lvl and make this information very easy to digest
Fascinating 😊 I always enjoy when your videos come across my feed I think you meant to put “impossible” instead of unpossible, but the validity of your content remains!
I take hydrolyzed collagen suplements for my joint issues. I honestly can't say I've noticed a cosmetic difference. Though that could be because I'm 19 years old, I suppose. Having said that, they suck. I hate taking mine, it's like drinking water with flour. I tried pills but you have to take so many of them to get the dose from the powder one. They are also so freakin expensive. So I cannot imagine why someone that doesn't need them would willingly take them, but to each their own.
I need it for my joints too. I take a Walgreens brand tablet called Triple Action Joint Health, which contains only UC-II collagen and undenatured type II collagen (the other 2 components are boron and hyaluronic acid) but it's only one tablet a day which is really nice. I tried taking powder too, which it claims you can mix it in anything, and I ruined a perfectly good cup of coffee.
Much more delicious! 😋 Although it’s suggested that whole collagen doesn’t absorb as well as hydrolysed, and requires a higher level of skill to prepare 😆
@@LabMuffinBeautyScience Can collagen be hydrolysed in household cooking? Would adding vinegar or lime juice help catalyse the hydrolysis? How about using a slow cooker? I recall that when I cooked chicken thighs or even a whole chicken in a slow cooker, the cartilage just totally dissolved.
Hi Michelle, I generally don't leave comments on RU-vid as a personal rule, but I'm compelled to make an exception because i want to express my gratitude to you and your team for making some of your expertise so accessible to the public. Thank you for doing what you do with your channel. I have learned a lot about skin and it has been invaluable to me as a non-specialist to be able to access trustworthy information and in such a succinct and comprehensible way. I have Classical-type Ehlers-Danlos Syndrome, and I am homozygous for it (apparently this is unheard of), so I make really crappy type 5 collagen. Having fragile skin means I get all kinds of downstream skin problems with atypical, hard-to-diagnose presentations. I'm currently on a journey to learn and do what I can to optimize the good collagen types that I do have (in my skin but also ligaments, etc). So, I am grateful to be learning from you. This video was very informative! As a vegan with EDS, I am hoping both that hydrolyzed collagen peptides will get supported by more positive evidence AND that someday soon there will be some kind of low-cruelty option. Because i don't want to eat modified cow skin, I'm currently trying out taking a combination of soy protein (for the right amino acids...I hope), vitamin A, and vitamin C. It does seem to be helping! but 🤷🏻♀️ Now I'm curious to learn more about hydroxyproline, and retinoids. Eg I'm curious what effect proline supplementation might have (there's a gram of it in a scoop of my soy protein). And, I don't have acne but now I'm wondering if retinoids could be useful anyway. Or any differently than what I'm already doing with oral vitamin A and (topical) glycolic acid. Thanks again - you rock!
Very interesting 👍🏻 Is hydroxyproline small enough to penetrate the skin barrier ? Definitely would love more videos on AA, peptides and collagen since they are in some ways the most promising ingredients in skincare.
all i can say is that it works for me 🤷🏼♀️ i am 30, started to get a deep nasiolabial fold at 27. i look better now than 3 years ago! i use alpha foods supplements. a ton of them, their green powder is great, too! plus exercise, very clean diet and good skin care 👍🏼 but i notice when i slack on my daily collagen.
@@donovandugard3167 yes i use retinol too. i use a lot of paulas choice skin care. vinoperfect from caudalie is also really good. don’t forget sunscreen!
@@BlondeQtie Thanks for your answers :) I'll buy a Paula's choice retinol, I already have a good diet , at least I try, but my work didn't allow me to sleep and workout as I would like to, I'll try collagène supplement,.hope it could help!
A bit of a side step from this. But I'd love to hear your thoughts/suggestions on good vitamin/supplement brands in Australia Michelle. I've been interested in getting some but all the ones I come across seem to either be cheap and ineffective or a straight up scam with sketchy company practices 😬
Omg finally! I've been asking this question to so many professors and none responded, they just looked at me like I'm a idiot for asking 😂 Thank you for the explanation!
Coming for Dr Carl is a bold move 😛 but luckily he’s the kind of dude who will probably watch your video and then go back and do some more research and agree with you 😊
For people who do not know, an in vitro study is done on cells in a flask. This is the first step in a clinical trial. Then you move to animals then humans. The problem with in vitro studies is that it can work on the particular cell that you're working with, but when you put it into something as an animal or a human, you're now dealing with entire organ systems. Something that won't harm a particular cell might harm a liver or a kidney. Or if it passes through your stomach it might get dissolved in stomach acids. And when you look at putting amino acids or something that is broken down from something else into a complete body system, there's a good chance it will never make it to where you think it will make it. It's not like it can say I'm going to target the skin only.
The translation to organisms issue isn't really relevant here though, since the hydroxyproline-containing fragments have been detected in blood after oral intake in human trials and the lower dermis where these would have their signalling effect are well supplied with blood. The big unknowns now are dose and effect.
@@LabMuffinBeautyScienceYes but you mentioned in vitro studies had shown this. And you really cannot necessarily correlate in vitro with in vivo studies.
@@LabMuffinBeautyScienceYes, but you mentioned in vitro studies concerning this. You cannot correlate in vitro studies to in vivo studies necessarily. And no I didn't get this from Wikipedia. I've been doing in vitro experiments since graduate school. Way more years ago and I wish to remember right now lol
Great video Michelle! There goes my dream of sipping collagen on my coffee and look 20 years younger after! I guess I'll stick with sunscreen and retinoids. Thanks for sharing.
Umm... seriously give it a try. I know scientific studies haven't proven much but a lot of people have reported skin, hair and nail improvement from consuming it. Also, it's good for joints and gut. Obviously, this information is only anecdotal but even my dietician recommended it.
Do all 3! I do & I feel soooo much better! It is helping with my IBS-D as well... I'm very pleased with the results of the collagen peptide powder I take & it's only been a month🤗
@@katrina374 i use the alpha foods collagen powder. they have good supplements! for vitamins and HA i use nature love or natural elements. all on amazon, but i also get them in my local stores.
I'm taking hydrolyzed collagen (from beef) primarily for my joints, and if it benefits my skin as well, all the better. I've read reviews of significant improvements, especially with people of 50+.. so I am hopeful.
I find it best and better to have soups and broths with fat and lots of nutrients like Gori Guk (korean ox tail broth!) c: It taste warm and nice in winter and revives alot. Specially thru rough cold (But I suggest make Tak Juk - chicken rice porridge. You can add lots of nutrient dense ingredients
I take a collagen supplement for my joints. I knew that collagen you consumed got broken down, but I assumed that having more hydroxyproline in my diet would mean my body would make more collagen/make collagen more easily. I have a connective tissue disorder that's more important to me than getting wrinkles!
Hydroxylation of proline is a post-translational modification. Genetic code still only uses the 20 protienogenic AAs. You cannot charge a tRNA with hydroxyproline and use it to make collagen. 0% of the hydroxyproline in the collagen you eat will go into the collagen your body makes. Any protein your body gets will be just as good!
I haven't included collagen into my routine bc I know the evidence is weak but I do see how many people swear by it. I've toyed with eating a small amount of jello everyday for its cost effectiveness!
Well I will just leave this here as my personal story: In 2021 I get an onset of back pain (lasted more then 2 weeks so I knew it had to be lumbar disk buldge or hernia). MRI done and L5 and L4 buldged with L5-S1 being 90% spent and almost completely dried up. Tried PT, spinal decompression and it helped a bit but pain was still there. Started supplementing daily with the following: Collagen Peptides (Bovine) - 20g Glucosamine - 1000mg Chondroitin - 1000mg Vitamic C 2000mg Vitamin D 6000 UI Vitamin K2-MK7 100mcg Magnesium Citrate 400mg Boron 4mg Selenium 100 mcg Zinc Picollinate 22mg Liver Cod Oil (15ml) - It was also source of Vitamin E and A. Month after month I started feeling better and the pain got much more tolerable. I could walk for long periods and also slowly start working out again. 6 months in I do another follow up MRI, my L5 and L4 bulgde rectracted by 3mm and my L5-S1 showed improvements in rehydration and now seemed to be only 60% dehydrated! Noticable effects were also much thicker hair, stronger nails, no more popping sounds in joints, improved skin quality, better sleep, just overall better wellbeing. Probably not all just thanks to Collagen but all of this together worked and continues to work. And I turned a very bad clinical picture around and even my doctor now is amazed how much better I have gotten from just daily stratches and this supplement stack.
Can you talk about fruits and veggies for skin collagen/youth? Thank you so much! Very grateful we have your reliable and credible scientific opinion in that part of the internet 🧖♀️
I wonder if the collagen that's found heavily in certain foods would react similarly to the collagen supplements? As it'd make sense if our bodies were able to absorb and use it more efficiently in this form
All I know is that when I drink collagen powder, my stomach and intestines heal faster when I have inflammation. Like a lot faster. Like days opposed to weeks…
I'm interested in if HA taken as an oral supplement has an benefit I wouldn't deny my dog is on HA and I may have tried it out but don't know if it's worth buying more for both of us (me and patches lol)
I have a question!! May I ask what the topical and ingedted impact of aloe vera on collagen conservation and production? I've seen some budding studies in it, but not a lot, I suspect perhaps it's measured as effective due to increase hydration?
You mention that collagen contains hydroxyproline, a non-canonical AA. I feel that proponents of collagen will use this point to incorrectly say that even after hydrolysis in the stomach, the hydroxyproline will be incorporated into new collagen. That's wrong because hydroxylation of proline is a post-translational modification. Genetic code still only uses the 20 protienogenic AAs. You aren't gonna charge a tRNA with hydroxyproline and use it to make collagen. 0% of the hydroxyproline in the collagen you eat will go into the collagen your body makes. This point cannot be overstated.
I've never seen the whole video of this particular guy but he could be talking about college and supplements for people who have connected tissue disorders. There are two different reasons a doctor will talk about college and supplements. So I have a connective tissue disorder that affects my collagen I have ehlers-danlos syndrome and people in my community try to take so many different forms of collagen in order to help and I've only ever see them get worse because they're not working out and because the supplements I guess are not working. I have to agree with this doctor maybe it helps your skin maybe it helps your body overall look better but I really don't think that it actually helps you with your joints not popping out of place. With this condition all of our joints will dislocate which means they pop right out of the joint and for a lot of us this is extremely painful and we have to live like this forever because there's no treatment and no cure. So I think that he's mostly talking about this because this is a mean reason why a lot of people take collagen supplements not really for their skin but mostly for their joints. What do you think?
Nah, he specifically talked about skin in his reel, and he’s said elsewhere that all proteins break down to individual amino acids before going into blood (not true) and each amino acid has no memory it used to be in collagen (not true because hydroxyproline)
I take it as a source of protein…is that still valid? And any thoughts on marine vs bovine collagen powders? I know they say that bovine is more complete with the “types” it contains.
Collagen isn't a great source of protein, it has a limited range of amino acids, plus it's more expensive than something like whey or pea protein powder.
Anything can damage the liver in high enough quantity. I say try it first since it's just broken down protein anyway & you're taking it in a controlled dose (3 grams of collagen powder twice a day, for example). I'm doing the same 🤞
Honestly I don’t know if I was sweating in my sleep last night but it’s winter here in Australia and I woke up with an Afro. Which is not common, I straighten my hair I’ve never been this fluffy haired in my life, one week of taking collagen
Sunscreen and a retinoid for me :) Not sure if a healthy diet helps collagen production but I eat loads of fruit and veggies 🤞🏽A lot of collagen products come from murdering animals which I don’t partake of anymore, although I’ve seen plant-based collagen skin care advertised but I haven’t looked into that yet…
You make me confused even more. So collagen could work but the evidence is still weak? And still it’s better to use retinoids and sunscreen than taken collagen supplements. It could work but still not recommended?!?!
The effectiveness of traditional collagen supplements isn't strongly supported, and there's probably even less research on plant-based collagen blends (animals make collagen). I'd say if you want to try it out then go for it, but remember that your body makes its own. I support anyone's decision to opt for plant-based products which are much gentler on the environment and don't require the systemized killing of animals .
If the Law of Conservation of Matter is true, then your body can't make collagen from nothing, right? Therefore if you use sunscreen, vit C and vit A but don't have the amino acid signals or building blocks, how would new collagen be made?
Nope, and the collagen in meat is in a less indigestible form - there's a study where there were blood measurements of collagen taken after eating various sources
@@LabMuffinBeautyScience interesting. Can you provide citation? What’s the ratio? So 1g supplement is equivalent to 10g meat to produce same hydroxy proline concentration in blood?
