CAR T Cells: Beating Cancer with the Immune System

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Doug Olson's terminal cancer was miraculously cured through genetic modification of his own immune cells. While this sounds like it's straight out of a science fiction novel, many cancer patients are currently receiving this revolutionary new cancer treatment: CAR T cell therapy. Learn about the mechanism, side effects, and the exciting future of CAR T cells in this episode of Medicurio.
Please go to my website for the video transcript, references, and extra info about the video:
• Doug Olson’s Story
• What’s the Fuss About Co-Stimulation?
• The Natural Cancer-Killing Ability of the Immune System
• New Ideas for CAR T Cells
• Hypogammaglobulinemia, CRS, and ICANS
• Thank You, Alpacas, For Your Nanobodies
Website: medicurio.ca/2023/09/04/car-t...
Timestamps
00:00 Introduction
01:30 T cell signaling mechanisms
03:32 How T cells destroy infected cells
04:46 Chimeric antigen receptor structure
07:03 CAR T cell manufacturing
07:53 Approved CAR T cell therapies and clinical trials
09:28 CAR T cell therapy side effects
10:37 The future of CAR T cell therapy
12:56 Outro

Опубликовано:

20 июн 2024

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Комментарии : 39

@JAB6322 9 месяцев назад

Man its been 3 years since you uploaded this. Your presentation animation and style are simple, straight to the point and eye catching. 😍

@sarveshanand2008 9 месяцев назад

Wow after 3 years medicurio is active back. By the way thank you medicurio for uploading on cart cell therapy. It's really helpful

@vshshshsvsbbdizk 16 дней назад

I am preparing for an presentation of car-t cells and I would like to thank you because your video helped me to understand everything clearly.

@garygenerous8982 9 месяцев назад

So glad to see you back and what an amazing video. That was so interesting and informative. Can’t wait for more.

@ChaseTrent 9 месяцев назад

Woah, I actually forgot about this channel. Super glad I got a notification!

@mussabm2981 2 месяца назад

Amazing channel pls don’t stop your narrative is so soo unique and grabs attention. I really watch so many medical, science-related channels but yours are currently the best i have watched. Your graphics. Your details and information are things you don’t see in other channels

@amangandhi1182 10 дней назад

Very good explanation. Continue making such videos.

@MrCythos 9 месяцев назад

You're back! Excited to watch!

@90klh 9 месяцев назад

So CAR T cells are like really trigger happy guards given a license to kill (no secondary message needed to activate)

@ikeoluwaonasanya7105 3 месяца назад

BMT nurse here! This was so helpful! Thank you!

@albrigo 2 месяца назад

As an experienced health professional, I'm impressed to see how a graduate student explains in a simple and educational yet scientific way such difficult pharmacological concepts. I encourage you to continue like that, and I am pleased to follow your videos!

@saraisantiago5154 4 месяца назад

You're so great at explaining difficult Pharmacology concepts and medications! You should do more videos on Meds like antidepressants and anxiolytics. The videos you have though are definitely getting me through PA school. Big thank you for that!

@amirhosseinrahbar9368 2 месяца назад

So accurate. Thank you

@hodafazaely2641 3 дня назад

Many thanks for it. You send important information as quickly as feasible.

@PedroOjeda 9 месяцев назад

My lab works on CAR NK cells. Same killing ability of T cells, no cytokine storm since NK cells do not release as many cytokines

@mariyanedeva6016 15 дней назад

Can we benefit from your lab as patients or you are conducting trials ?

@niraxlevi9930 13 дней назад

@mariyanedeva6016 nothing happens without trials unless you want to join the trials

@nazgu1 9 месяцев назад

Yay, he's back!

@Alex-mq8jb 2 месяца назад

this was just great

@iRemmi 9 месяцев назад

welcome back!

@waelfadlallah8939 9 месяцев назад

You're making history right now 😅

@justafellab7677 5 месяцев назад

Great to have you back

@livnorium4207 9 месяцев назад

The king is back 💪

@harryli5979 9 месяцев назад

Brooo you are back. Love your vids. I was just watching one yesterday

@Negarnorz 2 месяца назад

this video and the information you collected are really amazing and useful. thank you for this brief explanation based on really good papers that you had chosen .

@Miruoart 9 месяцев назад

Omg welcome back!! 🎉🎉🎉

@akk6783 2 месяца назад

Nice graphics and clear explanations.

@Amalistruzione 5 дней назад

Amazing content. Thank you

@SupLuiKir 9 месяцев назад

We don't necessarily need a universal CAR T cell. The process is expensive because right now it's artisanal. You need teams of qualified technicians to perform every step of the process. Once you can slot in the bag of blood received from the hospital into a machine and reliably receive the modified CAR T cells with minimal oversight, a massive portion of the costs will be eliminated. From there, the machine can simply be produced in enough quantities that the economy of scale phenomenon takes hold.