Algorithm can be implemented in suitable programming language. Here are some details and references: ------------------------------------- Online server: www.biogem.org/tool/chou-fasman/ Original papers: 1.Peter Y. Chou, and Gerald D. Fasman. Prediction of protein conformation. Biochemistry. 1974 Jan; 13(2), pp 222-245. 2. Peter Y. Chou, and Gerald D. Fasman. Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins. Biochemistry. 1974 Jan; 13(2): pp 211-222. Source code in C++: github.com/hassan11196/Chou-Fasman Source code in Python: github.com/greg-gardner/Chou-Fasman-Protein-Prediction