Thank you for a great lecture. You can't imagine how I laughed when you said streptokinase was a "prototype". I had to give that crap in the early 1990's to a guy with a central line in his axilla. He was going through DT's, and the medical residents didn't quite grasp the concept of Librium. Also, I very much appreciate your understanding of economics in medicine. So many providers don't even know what a "Wazoo" is, much less when it needs to be wiped!
First, a massive thanks for the time and the effort for this great video. As of now I'm an incompetent self studying biology student and aspiring doctor studying med topics way ahead of my time. This video should have brain damaged me but you explained everything so well that it was easy to follow, a few double takes but I got it all down in one sitting. I do have some questions for you: 1 - Since I can't find any intravascular trauma that doesn't first begin with external trauma (such as blunt force or cuts that expose TF,) doesn't all clotting therefore begin with the extrinsic pathway? 2 - The intrinsic pathway starts with this kallikrein which takes factor XII and activates it, creating XIIa. What causes the kallikrein to come about, or more straight to the point what kind of event initiates the intrinsic pathway independent of the extrinsic pathway (if the answer to question 1 is 'no'.) Again, monumental thanks. Your video is the first one I've been able to understand and actually make notes on. Cheers.
Very useful. I enjoyed the clinical part of it. I suggest that u draw everything from advance so it wouldn't take time. Other than that it was very nice.
