Тёмный

Coronavirus (COVID19) Update: Fairly Rationing ICU Care 

JAMA Network
Подписаться 218 тыс.
Просмотров 21 тыс.
50% 1

Hospitals need ways to make rational fair decisions about who gets ICU beds and ventilators if COVID-19 patients overwhelm capacity. Douglas B. White, MD, MAS, Director of the Program on Ethics and Decision Making in Critical Illness at the University of Pittsburgh, discusses a framework for making those decisions. Originally streamed Friday March 27 at 12 noon CDT (GMT-5).
Read the Viewpoint by Dr White: jamanetwork.co...
Read the proposal summary at:
ccm.pitt.edu/s...
• Free CME for watching this video is available at ja.ma/COVIDcme
• Coronavirus Resource page from the JAMA Network: ja.ma/covidyt
Topics discussed in this interview:
Could you say a bit about your co-author, Bernard Lo? (0:55)
You're an ethicist and an intensivist. How did you combine these two disciplines? (1:18)
The focus today will be on ventilators and critical care beds. But how do you think about rationing in the broader sense? (1:58)
Categorically excluding large groups of patients from receiving mechanical ventilation Is ethically problematic (4:08)
It is ethically insufficient to solely focus on survival to hospital discharge (6:31)
Were there other models that you drew on besides the lung allocation scoring system? (9:02)
Recommendations for a multiprinciple allocation framework (9:46)
More guidance is needed on withdrawing life support from one patient to provide it to another (10:06)
In ICUs, after someone's been on a ventilator for a long period of time, there are decisions made about how long they should remain on a ventilator. Are these situations different? (12:08)
Can you talk more about this framework that you've helped develop? (13:05)
Do you know if any of this approach has been used in Italy? (14:49)
I have enormous respect for Maurizio Cecconi, MD and what he has been going through in Italy (15:48)
So how is this document being used at this moment? (16:43)
Creation of triage teams (19:02)
Allocation criteria for ICU admission/ventilation (21:00)
What happens if you have 3 patients with acute respiratory failure but only 1 ventilator. (Secondary criteria) (24:24)
Reassessment for ongoing provision of critical care/ventilation (27:27)
Different cultures and religions view these issues differently. How does this framework address that? (29:36)
How do you think about the rationing of tests and personal protective equipment (PPE)? (31:25)
Do you have a sense of why such a large number of health care workers are getting infected. (33:31)
Is it ethical to double ventilate on a single ventilator knowing that this might be harmful to some patients? (35:01)
Hospitals and nursing homes are limiting visitors. Will families be able to visit patients dying of COVID-19 in ICUs? (36:51)
#JAMALive #Coronavirus #COVID19 #SARSCoV2
• Earn Free CME credits by watching JAMA Livestreams and completing a brief questionnaire. Claim 0.5 credits for each video at ja.ma/covidqa
• Coronavirus Resource page from the JAMA Network: ja.ma/covidyt
=====================================================================
To watch all the #JAMALive Q&A's Visit: ja.ma/covidqaytpl
Don't forget to hit subscribe or click ja.ma/subscribe
#JAMALive #Coronavirus #SARSCoV2
---------------------------------------------------------------------------------
For more from JAMA
• www.jama.com
• / jamajournal
• / jama_current
• / jamanetwork
Follow the #JAMANetwork
• www.jamanetwor...
• www.jamanetwork...
• / jamanetwork
• / jamanetwork
• / jamanetwork
• / jamanetwork

Опубликовано:

 

8 окт 2024

Поделиться:

Ссылка:

Скачать:

Готовим ссылку...

Добавить в:

Мой плейлист
Посмотреть позже
Комментарии : 83   
@kurtfisher1379
@kurtfisher1379 4 года назад
The analysis of the worst case scenario for ventilator supply does not include discussion of the ethics of the CDC not recommending the use of 3D printed, but unapproved, ventilators and pseudo-N95 masks. There are large groups of 3D printing enthusiasts who are presently stymied by the CDC and FDA not deploying a standardized approved design. When is the use of an unapproved ventilator or mask device appropriate within the context of a worst case supply case?
@joseonwon2797
@joseonwon2797 4 года назад
Seriously? (Punctuation matters)
@kurtfisher1379
@kurtfisher1379 4 года назад
@@joseonwon2797 Yes, seriously. www.wsj.com/articles/lacking-ventilators-hospitals-seek-out-alternative-device-11585154579. The ethicist in this video essentially replaces a numerical rating scheme based on life years saved in substitution of categorical exclusions based on age. The end result is the same - do not serve the elderly -although the numerical rating scheme may be more emotionally satisfying to clinicians. My question goes to practical responses seen in Italy and as discussed in Pennsylvannia in the WSJ article where a sufficient number of ventilators are not available and practitioners turn to creating improvised ventilator devices. Thinking as well as punctuation matter.
@marchanson711
@marchanson711 4 года назад
It makes sense to consider all of these very real clinical judgements. It was expected in light of all the factors at play here.
@MaeV808
@MaeV808 4 года назад
The title alone is sobering ... even after all the images and videos of ICUs worldwide being overwhelmed with patients.
@jmer9126
@jmer9126 4 года назад
Forgive me, but the first ones to be deprived of resources should be those politicians who dismantled public health readiness, delayed response, refused to provide adequate testing, equipment and PPE, and put the financial greed of themselves and their cronies before the needs of the people they supposedly serve. There’s a special hot place waiting for them,
@meredumais4934
@meredumais4934 4 года назад
One doesn’t have to believe in that “special hot place” to agree about where such monsters belong in any line of patients awaiting top-notch care and resources : *at the very back !* This clinician/ethicist is marvelous. His sense of uniform compassion is impressively evolved, to put it mildly.
@sandyb1184
@sandyb1184 4 года назад
The Trump administration dismantled the US Pandemic response team in 2018 to save costs.
@johnmeyer3366
@johnmeyer3366 4 года назад
Really?
@sandyb1184
@sandyb1184 4 года назад
@@johnmeyer3366 Yes, look it up.
@michaelmiller1131
@michaelmiller1131 4 года назад
Shouldn't the goal be to reduce the mortality rate? Allocating a ventilator to a younger person, who may well survive w/o it while condemning to death the elderly, seems counter intuitive.
@hocndoc
@hocndoc 4 года назад
That's where medical judgment, on a case by case, comes in. By the time there is a shortage, if there is a shortage, the docs on the frontlines will be experienced & better able to triage. That being said, I don't think I could remove one patient in favor of another.
@hocndoc
@hocndoc 4 года назад
Against the patient's will, that is.
@justaguy1679
@justaguy1679 4 года назад
I think the decision is already made “ventilation is necessary” to live. So now they have established criteria than will be considered in total as to which patients will be vented 1st is the absence of enough to go around. If a person can live without it, they wouldn’t be in the “lottery” so to speak.
@gulfgypsy
@gulfgypsy 4 года назад
In a perfect world where the ventilators *and* the qualified nurses to take care of patients on ventilators in an ICU --- Such might be possible. But both ventilators and staffing are in short supply. At that point triage bast on criteria for most optimal outcome, in necessary. And the reality is that a very elderly person with ARDS brought on by CoVid-19, even without other comorbidities, is at such an increased risk. Palliative care is the most compassionate and ethical course of treatment. Consider this: An elderly patient with CHF or advanced dementia or health issues due to uncontrolled diabetes *and* a patient who is in their 40's, otherwise healthy, no comorbitities, both need the one remaining ventilator in the ICU. Who would *you* ventilate?
@michaelmiller1131
@michaelmiller1131 4 года назад
@@gulfgypsy -- The recognized purpose of "TRIAGE" was to attend to the most severe first. Let's stay w/ that. It is not the role of healthcare to deny treatment and arbitrarily decide who lives and who dies. Of course, if a younger person is more severe, the ventilator should be used there. But, considering the more likely survival of a younger person, the ventilator should go to a more severe need, regardless of age.
@sophieb30
@sophieb30 4 года назад
Thank you.
@richb2229
@richb2229 4 года назад
Some very difficult discussions and choices that may have to be made here in the US. If the goal is to save as many patients as possible and these difficult decisions are being made I don’t see how how it would be ethical to allow family members to be exposed to these conditions. That’s a recipe for even greater disaster.
@eduardohoover2127
@eduardohoover2127 4 года назад
My viewpoint on the related topic of the standard for ethics of euthanasia is that it’s more ethical to weigh salvageable viability on the patient’s current and projected quality of life rather than the patient’s current or projected ability to contribute to society. Thus it’s morally irksome that in the hypothetical case discussed that medical personnel would get privileged treatment. I’m a retired Catholic zuegmatographer so my opinion means little and I’m apologetic for the harsh terms I used. Absolutely a wonderful topic of discussion. As a former UPMC Magee employee thank you. I also worked at NIH so hats off to Dr White and Dr Fauci.
@sandyb1184
@sandyb1184 4 года назад
I feel that in any hospital that is overwhelmed and needing to make these challenging decisions, there is no place for family members. When we cannot waste resources due to value decisions, we can also not waste time and resources to allow such visitations. The ultimate goal is to save as many lives as possible, while protecting the healthcare workers to the maximum we can achieve. Visitors do not fit in to that. I will have a talk with my family members that should any of us require hospitalization, we would understand that other members of the family cannot be present while that treatment is being administered, including right up to any terminal conclusion. It is just safer for all, including healthcare staff. It is a sad reality of a devastating crisis that we must all be able to accept.
@SteveL4
@SteveL4 4 года назад
That's exactly what they're doing in Italy. The family is called when the patient passes away, that's all.
@barbarahenninger6642
@barbarahenninger6642 4 года назад
You are mighty comfortable playing God.
@michaelmiller1131
@michaelmiller1131 4 года назад
A poor solution is not allowing anyone with a vested interest to speak-up for the patient. Didn't work for the Nazis.
@joseonwon2797
@joseonwon2797 4 года назад
To do no harm breads compassion and empathy cultivates understanding
@sandyb1184
@sandyb1184 4 года назад
@@barbarahenninger6642 Maybe God could send more ventilators and we wouldn't have to make these decisions.
@ChiliMcFly1
@ChiliMcFly1 4 года назад
Very interesting and trying decision making processes. Good luck and God bless.
@jenniewilliamsmural
@jenniewilliamsmural 4 года назад
Im a nurse at a hospital north of NYC. Governor Cuomo announced that they'll shift ill people from NYC to hospitals in the state. These urban presumably young vital people will likely change the ethical ecology and the outcome for rural people like me. Thanks for the great discussion.
@pattipepper2964
@pattipepper2964 4 года назад
Can you add closed captioning please.
@buzaldrin8086
@buzaldrin8086 4 года назад
Click on the CC icon.
@pattipepper2964
@pattipepper2964 4 года назад
@@buzaldrin8086 Thank -you
@jameswright6316
@jameswright6316 4 года назад
*** NEEDS TO BE RESEARCHED *** The most direct goal of treatment should be to "treatably prevent" or greatly reduce the interactions between the Type 2 Neumocytes and the viral load. Another goal is to mechanically prevent attachment of the S-Spike Protein to ACE-2. So, how can we: 1 - Attack the virus directly while in the lungs? 2 - Interfere with the attachment? The normal way by which the human body interferes with things that want to harm the lung is to create mucus. That's the role of the mucous membranes. They create an immunological fluid which collects particles [ eg viruses interacting with the cilia of the respiratory cells ] and move them away from the cells that they may be "digested" by the body - OR - cast out by the organism with a hacking cough. So, how do we cause the patient to create more than a normal amount of mucous in such a way that the effect is reversible? Also, the effect of the virus upon the alveoli is basically to create a form of pulmonary edema. The alveoli drown in fluid. So, how do we: 1 - Attack the virus directly while in the lungs? 2 - Cause the body to create more mucous than is normal for the organism? 3 - Create a situation where the fluid around the alveoli [ basically pulmonary edema ] is mitigated? The inhalation of 91% isopropyl alcohol - aerosolized - eg inhaling from a half full, shaken bottle of 91% alcohol - accomplishes all three goals in a very treatable way. 1 - We know that 70% alcohol is enough to destroy the protein envelope around SARS-COV-2. Inhaling 91% which has been aerosolized will actually be the inhalation of a concentration less than 91% due to the presence of some water vapor in the patient's normal room air. However, a lot of the aerosol should be over the 70% concentration level. When that alcohol comes into contact with the virus - the virus will be destroyed. That is a chemical necessity. This will destroy viral load that has been inhaled - as well as new viral load budded off from the Neumocytes. 2 - Inhaling the alcohol will cause the mucous membranes to activate. This will turn the "dry cough" into a "wet cough. That wetness is an immune system material created to protect the cells from damage. That material will - in small amounts - coat the surfaces of Type 2 Neumocytes and block their interaction with the S-Spike proteins. Further, those viruses that are not directly destroyed by the alcohol - will be captured by the mucous for discharge or digestion. [Hot peppers contain Capsaicin which activates the mucousal membranes. Also, the flush that occurs when one eats a hot pepper can interrupt the transmission vector of this virus.] 3 - Alcohol [ Ethanol ] Inhalation has been used successfully to treat Pulmonary Edema. Here, one would be using Isopropyl alcohol instead of Ethanol because it is more common for patients to have access to it - without overloading the healthcare system - and because it causes the production of fluid rather than fully discharging it. To discharge the fluid, treatment plans could include a second phase where the patient switches to ethanol - OR - the patient could take a decongestant such as Mucinex Day and Night. The goal is to break up the mucous - with the destroyed viral load within - and discharge it. So, to me, it appears that an Alcohol Inhaler offers the most direct possibility of treatment for this disease. Also, watch for the sore throat. It seems that there comes a point where the adenoids [especially] and the lingual and palatine tonsils get very sensitive and painful. [ squeeze a bunch of grapes - feeling is like point just before they pop and it lasts a couple days ] I offer that to be the point where a patient should stop with the inhaler and spend a few days on the Mucinex. And do not be surprised with the weird sound the voice makes as it seems the mucous? coagulates? in the larynx. [ I do not understand that. ] Also, after inhaling the alcohol for a couple weeks the sinus cavities will fill with snot. Blow this out normally. It will happen for a few days. I think the development of the "chunky mucous" aka snot - is useful for the body as an immune function as it collects and binds the viral load more efficiently than fluid can. Fluid mucous in the lung is good. Chunky mucous in the sinus is good there. The "wet cough" and presence of phlegm should be encouraged as long as deep breathing is maintained. The goal with this is to keep the intra-lung environment inhospitable to the virus without endangering the patient. I can live with uncomfortable. [ There are indications that one can be reinfected - a "wet cough" may reduce that opportunity.] I know this treatment plan works because I have just completed doing it. [Former Paramedic, Combat Medic, EFMB etc US ARMY] My wife, an RN with both BSN and MSN is doing so too. We live in San Antonio, Texas. The only side effects either of us have had is a slight light headedness. We have never practiced "deep breathing" and are getting a lot of air with every breath we take. I am seeing videos where others are beginning to describe their symptoms and they are all consistent with what I felt - except the fever. I started with the alcohol on 1 March due to cough, fatigue etc as a "preventative." Around the 14th I had a few hot flashes and quickly inhaled the alcohol. The hot flashes went away with no development of a fever. Thank you and I hope it helps - if it is considered. James Anthony Wright Thank you for your reply. I used this treatment as a preventative. I started when my wife and I began having a dry cough. This was a couple of days after the patients who were quarantined here in San Antonio Texas were told to go to a hotel. One of them went shopping at a large local mall instead. My wife is an RN who specializes in high risk OB. She, and I, began to feel fatigued, coughing etc and wanted to try to do something pre-fever onset. This virus has some HIV-like functions and other issues that appear to be attacking the immune system even harder after it begins to respond to the virus. I suggest the 91% isopropyl alcohol as an inhaler. I explained why in my original post. I have no idea what any other substance would do, except, do not use bleach as WW1 gas attacks proved that to be a very bad option. [A bottle of 91% isopropyl alcohol costs about $5 at the local HEB. Assuming patients can find it on the shelf - it should be available.] As for the autopsy, I have not seen it. It is hard to speculate because vaping, smoking, living in urban air pollution etc all have an effect on the lung. Mucous is a natural self defense mechanism of the body. I am not surprised that it would be present. The issue is having enough in the lung to prevent viral development - early enough - without creating so much that it becomes harmful. Dosing is a primary issue that I feel doctors need to research. Remember, alcohol inhalation has been used to successfully treat pulmonary edema. Also, the volume of aerosolized alcohol inhaled should be low. I only took 2 or 3 deep breaths with each nostril each session. Sessions occurred after coughs, heat flashes, etc. The goal is not to get intoxicated, but, to interfere with this virus. One thing I failed to mention in my original post was that the mucous can be generated by eating hot peppers. Capsaicin causes the mucosal system to flush. [ jalapeño = teary eyes ] That action interferes with the transmission vector of this virus. Hot Peppers - interrupt transmission - create mucous Alcohol Inhaler - perhaps put alcohol onto virus envelope - interfere with linkage in lung - treat the edema Mucinex - assist with the removal of excess mucous when it develops as outlined in my original post Of course, again, all of this should be researched and verified by doctors.
@h1jen1x
@h1jen1x 4 года назад
It's pretty evident you've invested likely hundreds of your personal hours searching for actual solution based management of the virus itself. Idk if ur a doctor? Or are you just a regular American who refuses to accept the pain, suffering and DEATHS officials agree to in their adoption of this glaringly flawed idea of 'flattening the curve'
@jameswright6316
@jameswright6316 4 года назад
@@h1jen1x Former US Army Paramedic, Combat Medic with the EFMB - married to an RN with her BSN and MSN with a specialization credential in High Risk OBGYN. We have been married 27 years. I lost faith in doctors the night one of them cut inflated trousers off a patient I saved and was transferring into the hospital. MAST trousers are the same as flight suits. They have bladders which push the blood out of the legs and into the chest to reduce the severity of shock. Proper way to remove them is to slowly lower the blood pressure. Cutting them off results in the blood rushing to the feet. That causes a vacuum in the heart which actually pops the valves - killing the patient. I refuse to blindly trust a doctor with my - or my wife's - or my family's - life. I always use the internet, my library and other resources to verify everything I'm told. Physician, heal thyself ! Also, it is very interesting to me that no one seems to be offering suggestions as to how we can treat ourselves at-home pre-hospitalization if we are diagnosed with COVID-19. That is why I posted my idea. Fauci and others seem to stalling the scientific process regarding hydra-zinc-z-pak as much as they can. Interesting !
@familiegeier4828
@familiegeier4828 4 года назад
I agree. Survival years, quality of life, QALY's, regional framing, the patient's will, and religious&theologic&metaphysic&ethic aspects (general, and the patients') have to be considered by a triage team. Nullius in verba. sg
@aartfx
@aartfx 4 года назад
Why don't we create US Pandemic Service. Draft (Quarantine) all who test positive to empty hotels (minor care facility). Crash course covid 19 specific minor, care giver. Free up RN, LVN Nurses for more intensive tasks in hospitals. If you tested positive you don't need protective gear if quarantined with others.
@sandyb1184
@sandyb1184 4 года назад
There was a pandemic response team up until a few years ago when it was cancelled by the Trump administration to save costs.. Poor decision don't you think?
@scarlet8078
@scarlet8078 4 года назад
Hello, it would be helpful if you discussed ways of optimizing PPE effectiveness. I'm a counsel for drug & device companies & while there have been no public statements re: the many HCPs being infected, I want everyone to know that PPE manufacturers & suppliers care deeply about this. When tested, the equipment has all met quality standards. No batches have been recalled by any major US supplier. This indicates infections are due to community spread, insufficient PPE supply &/or ineffective PPE use. Scientists & engineers familiar with PPE who've studied SARS-Cov2 believe certain qualities of this virus, including its "stickiness" for lack of a better term, result in infections due to minor user errors that are inconsequential with other infectious agents. For example, PPE should NOT slide over the skin, jewelry should be removed, nails cut & filed & users should avoid contact with any other sharp edges that can compromise PPE, etc. Some ER HCPs even use antibacterial moisturizers like Neosporin to prevent masks from moving on skin. It would be interesting to hear a discussion on these methods & if they help
@oohh1411
@oohh1411 4 года назад
Thank you, so it poisons you then you fight and you get it and you fight it again and then intensity can still poison you again until it is gone. I wish you all the best.
@carlitosmrv
@carlitosmrv 4 года назад
Great contents gents.
@johnmeyer3366
@johnmeyer3366 4 года назад
What bodies are responsible for conferring critical worker status? Who anoints them? Are democrat government decision makers, governors, etc, going to be found likely to save more lives in conservative healthcare settings administered by members of the republican base?
@jenniewilliamsmural
@jenniewilliamsmural 4 года назад
I agree with these guidelines except that I would add a lifetime contribution rather than simply years. Mothers and grandmothers keep our world turning. This is a very important discussion- thank you!
@Mike-01234
@Mike-01234 4 года назад
This should never have to happen in America because of a pandemic I could see this if we were attacked by nuclear weapons.
@deborahhebblethwaite1865
@deborahhebblethwaite1865 4 года назад
blastman8888 it sort of is.... without guidelines doctors faced with the emergencies like in Italy must take ventilation away from an older person and let them die . Those doctors are all going to have ptsd. If a patient dies without ever being on a ventilator this creates some distance and less of a feeling of killing someone. Also ventilating people who have lung issues before and the elderly do not get as good of an outcome. Their lungs can be quite damaged. Its isnt as simple as just saving lives. I am a senior and have allergic asthma, i will NOT be ventilated should the situation happen. I hope they would be merciful and put me out....
@sandyb1184
@sandyb1184 4 года назад
A pandemic can easily overwhelm the healthcare system and the resources of that system. It is simple, there are not enough ventilators for all who will need them. Had protocols been adopted early enough as in South Korea, the healthcare system may have stood a chance of functioning properly. Sadly, those excellent protocols were not adopted in the US and there will be needless loss of life above and beyond what would have happened otherwise. The US squandered the precious time that they had to prepare adequately and the citizens will pay the price.
@deborahhebblethwaite1865
@deborahhebblethwaite1865 4 года назад
Sandy B before the internet and i lived many years before that time we would not know what hit us. We would simply react. I sometimes think i like it better that way. Live life like it was your last day. None of all this anxiety with news and should ofs......
@justaguy1679
@justaguy1679 4 года назад
“Should” is such a difficult concept.
@sandyb1184
@sandyb1184 4 года назад
@@deborahhebblethwaite1865 We were very fortunate to have the news of what was occurring in Wuhan. That news, has allowed us to prepare , however imperfectly, for this. I am incredibly thankful for that, because with all that news (and anxiety) lives will be saved. Many, many lives have already been saved by the imperfect preparations of many countries. I would gladly suffer a lot of anxiety to spare a family the devastation of losing a loved one. Technology has been a very important gift to us, and it will result in lives saved. I would never wish to go back to a time where we had no advance notice and many more lives were lost (and there was still extreme fear and anxiety about 'the unknown' disease).
@andreawalker2535
@andreawalker2535 4 года назад
Well, no surprises here. No families present in this crisis, in order to advocate for the patients.
@sandyb1184
@sandyb1184 4 года назад
That is the unfortunate reality of a crisis. This is not normal operation of healthcare. We must all understand that. We must all accept that this is one arena where decisions must be made by adhering to well defined guidelines, and must ne carried out by the healthcare professionals willing to step into that life threatening arena in the first place.
@andreawalker2535
@andreawalker2535 4 года назад
I was one who was near death in November 2019, hospitalized without any family with me in the first two days, I was told to declare a DNR for myself because I was so sick with 4 major acute morbidities.I refused and then I did receive the care needed, including Bpap, a week in ICU and 14 days in hospital.total. I will expire if I contract Covid=19. Healthcare professionals are not gods, even if they do save our lives. My hope is that, after this crisis, the health care rationing tribe will not prevail. Hospitals wanted the rationing of health care access prior to this. As I said to start, "Nothing new here."
@sandyb1184
@sandyb1184 4 года назад
@@andreawalker2535 Sorry for what you went through. I hope you are doing much better now. Many of my family will not likely survive Covid 19 if they get it. I agree that after this has resolved we must always fight for increased patient care, access and resources. But now, during this crisis, there is an overwhelming under supply of resources and very difficult decisions will be made. This lecture demonstrated that they have put in place very compassionate, logical and ethical standards for making those decisions. I applaud their efforts to make good guidelines for challenging times.
@andreawalker2535
@andreawalker2535 4 года назад
@@sandyb1184 Have this rationing been put in place?
@sandyb1184
@sandyb1184 4 года назад
@@andreawalker2535 Reports from Italy suggest it has been necessary. Most likely in NYC now as well. It is a simply matter of numbers. The only treatment in severe cases is ventilation and there are not enough ventilators to go around. The governor has made a special circumstance authorization to allow multiple patients on one ventilator but many experts feel this could be a very dangerous practice. New York City hospitals have responded with the statement, 'the only alternative is death'
@cassandrawarner78
@cassandrawarner78 4 года назад
Douglas be white
Далее
Dialysis for Chronic Kidney Failure
21:39
Просмотров 334
Bipolar Disorder Across Lifespan | DBSA Summit 2022
1:15:25