C-C Bond & C=C Bond Formation Reactions with Stereochemistry : ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-YqCH8AEccSw.html Oxidation & Reduction Reactions with Stereochemistry: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-qJoDhV4DX98.html Rearrangement Reactions with Stereochemistry : ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-Lat7VXgAJ8o.html
Dear Babachary ji, Heck reaction is performed in organic solvents using organic bases such as Et3N etc. Suzuki reaction is performed in a mixture of organic solvents (dioxane, DMF etc) in water system. Palladium catalysts are soluble in organic solvents e.g. Palladium acetate: Solubility: sol organic solvents such as chloroform, methylene chloride, acetone, acetonitrile, diethyl ether. Dissolves with decomposition in aq HCl and aq KI solutions. Insol water and aqueous solutions of NaCl, NaOAc, NaNO3 as well as in alcohols and petroleum ether. Decomposes when heated with alcohols. However, when bases (inorganic bases like CsF, Cs2CO3, Na2CO3, K2CO3 are used then water also used). Typically in a Suzki reaction the solvent system will be : 1,4-dioxane/water (9/1 ratio) and the Pd catalysts such as Pd(dppf)Cl2 and CsF are used.
Thank you Brahmi ji, Please follow these videos for more name reactions: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-0uWqtCi21N4.html Name Reactions alphabetical order: sites.google.com/site/venuschemistryacademy/home Wish you all the best.
Dear Pureti ji, Palladium catalyzed reactions involves a step of oxidative addition and this step is facilitated by high electron density compounds like organic (C-X) halides /pseudo-halides of sp2 carbons, and the rate of the addition decreases in the following order; C-I > C-Br >>> C-Cl >>> F. Aryl fluorides are almost inert. It is clear from the above order that the R-Cl is less reactive and R-F is almost intact. However, recently, facile oxidative addition of sp2 C-Cl bonds can be used by using electron-rich ligands such as P(t-Bu)3 or N-heterocyclic carbene ligands, and electron-deficient aryl fluorides can be coupled when PMe3 or biphenylylphosphines ligands are used. In general, most of the halides/pseudo halides like Alkenyl, aryl halides, acyl halides, sulfonyl halides, Diazonium salts and triflates undergo facile oxidative addition. I hope your question is answered. wish you all the best.
