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Digestion, Mobilization, and Transport of Fats - Part I 

khanacademymedicine
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How are fats digested, mobilized, and transported inside the body in the fed and fasted states? By Jasmine Rana.

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8 апр 2014

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Комментарии : 195   
@alisonhenley353
@alisonhenley353 5 лет назад
whoever is being mean, stop!!! LOL this woman is blessing us with her knowledge and all you guys can do is focus on the negative! you're awesome Jasmine!
@danilemark3642
@danilemark3642 4 года назад
her voice is anoying, ando nobody asked her to make a fake voice
@matthewbateman6487
@matthewbateman6487 2 года назад
@@danilemark3642 Yeah -- and at 2:08, she said Mac-Man, instead of Pac-Man.... Fake fan over hear...
@nikhiljaiswal2331
@nikhiljaiswal2331 8 лет назад
I'm sorry, but I honestly think she explained it really well. You have a talent of explaining ma'am. Clear, concise, and short. Keep up the excellent work. And no, your voice is not as others have said, it's great! Thanks for helping me prep for my MCAT :D
@zinedinelaichaoui9673
@zinedinelaichaoui9673 6 лет назад
ليا1ق9نوزتهدظتااالةقفغظظنتتلبباتاغت0
@jamesbedore9051
@jamesbedore9051 9 лет назад
I have been learning a lot about nutrition and how the body works so I can take better care of medical issues. Your videos fill a lot of missing pieces and are very understandable. Keep up the good work. Great voice!
@mattricca9508
@mattricca9508 5 лет назад
These videos are amazing! They present the information with the perfect level of complexity and depth, and they are so incredibly thorough-they are an invaluable resource for me as a nutrition coach. And for the record, the narrator’s voice is lovely 😊
@hannahhorsch5282
@hannahhorsch5282 7 лет назад
No idea what people mean about your voice... Seems like people can never be happy. Thanks for the video! I needed this.
@danilemark3642
@danilemark3642 4 года назад
it's a fake, high piched, cringy, anoying voice, simple as that
@vargvikernes4859
@vargvikernes4859 4 года назад
It's shitty voice trying hard to vocal fry . It's irritating to hear
@DinosaurKale
@DinosaurKale 4 года назад
I just found this video looking up fat metabolism, and all I see is four years of mean comments about a nice, normal voice.
@theclassroomdoc
@theclassroomdoc 5 лет назад
I sincerely hope you are a teacher because you are brilliant at it!!! Thank you so much for the generous time you spent doing this. I've subscribed and you will be my go to for all things biochem.
@ashishjain871
@ashishjain871 8 лет назад
This video is amazing :). Thank you so much for taking the time to produce this video. I am fairly impressed by how you have simplified the information such that it is readily understandable by laymen like me. I always wondered how fat is digested in our body.
@ahameedjamal6141
@ahameedjamal6141 9 лет назад
First of all you have an amazing voice, secondly the way you break it down it is so understandable and i am an engineer. Thank You very much you have been very helpful.
@LahiruRandikaDetails
@LahiruRandikaDetails 8 лет назад
You Guys are doing an awesome service.. Thank You so much
@sreenath1987
@sreenath1987 7 лет назад
There is a major mistake.... Its PacMan and not MacMan. 😬
@zannatul23
@zannatul23 7 лет назад
macman loooool
@genmasaotome3503
@genmasaotome3503 4 года назад
IRK?
@janjamesramos247
@janjamesramos247 4 года назад
it's a Big Mac burger, makes sense... lol...
@ekbergiw
@ekbergiw 4 года назад
Also, it's an imaginary Pac Man
@fmn2628
@fmn2628 4 года назад
Milenial mistake for sure.
@Keval_ek_insaan
@Keval_ek_insaan Год назад
This is so far the best explaination . Detailed but precise. Lol. I just fell in love with learning the process.
@yvetteb330
@yvetteb330 4 года назад
This is the clearest and most coherent explanation of this process I have come across. My professor explained it terribly.
@Mariatyra
@Mariatyra 2 года назад
Thank you so much for helping me understand stand this material for Human nutrition. Love when I understand what someone is teaching.
@Juls127
@Juls127 10 лет назад
Omg it is soooo helpful thank you so much. I'm a French medical student and it helped me a lot understanding my lessons for my finals thank youuuuu! Btw, i love your voice!!!
@lukasi6688
@lukasi6688 9 лет назад
Thank you very much. I had a very hard time understanding walls of scientific words on the internet, but this video is way easier to understand. You help me with my homework a real lot.
@Rakesh-zh9qh
@Rakesh-zh9qh 8 лет назад
u r makin my job easier.. thanku for al ur informative videos!!
@oblivyeon9308
@oblivyeon9308 7 лет назад
I can't stop laughing at that sudden "is" on that sentence around the middle point of the video.
@abdalla8558
@abdalla8558 6 лет назад
😂😂 i repeat it lots of times
@renatojosediaz1
@renatojosediaz1 5 лет назад
6:14 😂
@crazy-d1am0nd
@crazy-d1am0nd 3 года назад
Excellent explanation about this fascinating process, well done !
@mandanamashoof3015
@mandanamashoof3015 8 лет назад
Great explanation. Thanks for your great and hard work.
@jess100ize
@jess100ize 5 лет назад
This is so concise and clear. Thank you.
@israrkarim65
@israrkarim65 7 лет назад
The voice motivates me more to learn. keep going.
@davidvincent1932
@davidvincent1932 8 лет назад
wow, 45 minutes of reading condensed into 5 minutes (if watching 2x). Good job.
@theclassroomdoc
@theclassroomdoc 5 лет назад
You are a great teacher. Appreciate the free lessons. #gratitude
@loukraft7322
@loukraft7322 5 лет назад
Great process summary. I have a question. When lecithin or Phosphatidylcholine is used as a carrier to encapsulate a nutrient, is the release of this nutrient triggered in the first encounter with the lipase molecule or in the second encounter with the lipoprotein lipase in the blood?
@mrkristung
@mrkristung 7 лет назад
Very well explained. Thank you!
@sancho2005
@sancho2005 Год назад
Great video! God bless anyone who liberates knowledge
@billking2314
@billking2314 6 лет назад
Very clear, concise & extremely informative. Do you have similar lectures on carbohydrates and proteins?
@backstreetfan2887
@backstreetfan2887 3 года назад
Good information. The part about lacteals I didn't know before. Thanks.
@CST1992
@CST1992 3 года назад
Your voice is beautiful, and you also explained it clearly. Keep up the great work!
@razatoor3701
@razatoor3701 8 лет назад
Excellent piece of work.
@Kuvaji
@Kuvaji 9 лет назад
Very nice and simple! thank you :)
@nha8909
@nha8909 5 лет назад
your voice is so lovely! thanks !!!!! this was very clear and your explanation was very genuine
@ab-lz2gh
@ab-lz2gh 3 года назад
now understood properly, very beautifully explained thank you soo much
@j7ndominica051
@j7ndominica051 3 года назад
When medium chain fat is absorbed directly into the blood, does it go in as a triglyceride or is it broken down into fatty acids? The name of the MCT oil suggests that the trig. are entirely short, but natural substances like milk have mixed trig. and also work for quick energy delivery.
@kingot90
@kingot90 6 лет назад
I find her voice soothing. Well organized and informative video. At 3:41 she says that, "our body secretes something called bile from the liver." This is incorrect. The bile is produced in the liver but stored and secreted from the gallbladder.
@DavidEdwards-pc1sw
@DavidEdwards-pc1sw 7 лет назад
LOVE YOUR VOICE , IT MAKES ME CONCENTRATE , AND YOU HAD THE BEST EXPLANATION EVER !!!!!!! YOU`RE THE BEST , TACTICAL TEACHER . THANK YOU .
@rachelregalado9563
@rachelregalado9563 6 лет назад
Are the FAs of the C2 on the glycerol backbone cleaved? I thought they were left on the glycerol backbone, and then absorbed, and then once inside the endothelial cells, repackaged? Also, before entering the blood, don't the chylomicrons go to the liver first? There were a few details of this video that I thought were misrepresented, but other than that, thank you so much for the video. The way you described everything was easy to understand.
@pgiladyrosequeturas6842
@pgiladyrosequeturas6842 7 лет назад
Isn't it lipase only hydrolyzes the ester-bond in the carbons 1 and 3 of TAG? so the resulting products are 2 free fatty acids and a 2-monoacylglycerol? Just asking :) thanks for the vid though. its helping me a lot
@sshihale7
@sshihale7 7 лет назад
My Lady Rose Queturas I thought so too
@vbt1992
@vbt1992 8 лет назад
-Thanks for the Great Explanation , But Doesnt the Pancreatic Lipase Cleave Ester bonds of C1 and C3 , and leaves Fatty acid of Carbon 2 unchanged ? And shouldnt Bile Salts Provide a Micelles for Transport of Fatty acids and Monoglycerol into the enterocyte ? . Thanks :)
@shubhammk6922
@shubhammk6922 4 года назад
Vayne Manson you are right
@adamzeuspowell6424
@adamzeuspowell6424 10 лет назад
Does this mean that all our consumed fats get absorbed and transported before reaching the large intestine? If they don't. What would cause this lack of absorption and are they just considered waste and excreted at that point? Your videos are incredibly informative by the way, I'm just extra curious
@wantingtolearn2732
@wantingtolearn2732 8 лет назад
Are the lipoproteins mentioned that carry the fats, LDLs?
@TRXMOM
@TRXMOM 9 лет назад
hi really love the drawing and explanation. does any body know were is she drawing everything, like the program or where? lol thanks
@ucheobi7430
@ucheobi7430 4 года назад
Amazing explanation!!
@kp74952
@kp74952 6 лет назад
Ignore the ignorant comments from the guys who watch too much porn. Great video, very helpful, clear and concise with the right amount of detail. Nothing distracting or annoying about your voice.
@raanoooshh9296
@raanoooshh9296 5 лет назад
I did not find the voice annoying, it was actually very clear.
@susanaadamtey2138
@susanaadamtey2138 3 года назад
Thank you. This lesson was helpful
@xabdulaziz
@xabdulaziz 5 лет назад
Very nice, thank you so much ❤️
@d.2542
@d.2542 6 лет назад
thanks! helped me a lot
@murtadahassan263
@murtadahassan263 5 лет назад
اريد المقطع مترجم
@MrPokerblot
@MrPokerblot Год назад
I thought the burger was a ufo trying to catch the good gentleman’s attention. I like your illustrations. 😊
@rafiknabil2144
@rafiknabil2144 4 года назад
Great Video, thanks a lot
@queenhauwa5357
@queenhauwa5357 8 лет назад
NICE VIDEO AND ALSO NICE VOICE.
@swetaruparel3233
@swetaruparel3233 4 года назад
Very helpful !!! Thanks a lot...
@ismaelnaruto30
@ismaelnaruto30 4 года назад
wow thanks a lot excellent video
@26chrisb
@26chrisb 7 лет назад
Very clear, thank you.
@bamhen
@bamhen 7 лет назад
Very nice presentation. However, the packaging of TAGs is not made inside a protein molecule. Instead, the TAG are surrounded by a phospholipid layer (purple circles). These phospholipids have polar head groups (phosphocholine) and hydrophobic tails (fatty acids). On this layer (facing the aqueous environment) several proteins are attached.
@WillLiang
@WillLiang 8 лет назад
It's not just the voice, it's the enunciation as well.
@NoR3m0rs3
@NoR3m0rs3 8 лет назад
dont mock her lithp
@ab-lz2gh
@ab-lz2gh 3 года назад
sooo sweet voice. couldnt concentrate properly. have to listen again. but got the zyst.
@jordannemclean6467
@jordannemclean6467 Год назад
you are an amazing lady!!
@kristina9605
@kristina9605 3 года назад
So is does your body break down the cheeseburger fat differently than say, a fresh salmon fat?
@anjujambhalkar6351
@anjujambhalkar6351 5 лет назад
Great explaination
@brianknittle6642
@brianknittle6642 3 года назад
Awesome vid.
@liyuling1984
@liyuling1984 5 лет назад
anyone can tell which part of America is this voice from?
@onyx8862
@onyx8862 5 лет назад
thank u for my life
@exploremyideas7234
@exploremyideas7234 9 лет назад
Cheers for that Jasmine
@andrewtauma3090
@andrewtauma3090 7 лет назад
thanks the explanation..
@guillaume6373
@guillaume6373 2 года назад
Great video :)
@AxelZaore
@AxelZaore 5 лет назад
I'd pay for you to spell "chessburger" 100 times. Really. Great explanation as well, thanks!
@MK-cf1rm
@MK-cf1rm 3 года назад
people are actually hating on her voice? i really like her voice haha
@JS-rg7vo
@JS-rg7vo 4 года назад
Fantastic!
@ArjunKelaiya
@ArjunKelaiya 5 лет назад
Excellent!
@TheSweetalchemist
@TheSweetalchemist 4 года назад
How many hours of fasting for the fat cell storage to un-store the fatty acids & triglyceride and back into the blood stream for use?
@lethabonkadimeng3273
@lethabonkadimeng3273 4 года назад
For weight loss? I don't know but probably a lot of hours because even if you don't eat, the human body has BACKUPS to ATP production😂😂😂 like🙆🙆🙆 wow.
@tbcytdg1988
@tbcytdg1988 9 лет назад
Beautiful voice!...AND AN INCREDIBLE WORK!!!
@vidinfoful
@vidinfoful 6 лет назад
I am in the middle of viewing this video, and am thinking, "I really like this instructor." She explains everything clearly and concisely. I am also thinking, "Hmm, I really like the voice." I quickly check out some comments, and see that some have the opposite opinion. I am a guy, so I don't know, I really like this instructor's voice. Soothing, relaxing, but clear and bright at the same time. It's true that the voice alone can tell us whether we will like a person or not. For example, for me, when it comes to radio station hosts, generally speaking, the Jazz station hosts have the most pleasant and interesting voices.
@TheSuperawesomness
@TheSuperawesomness 6 лет назад
I know this isn't the point.... but did she say MacMan?
@Hussainishak
@Hussainishak 5 лет назад
Its a beautiful voice
@hybeofficial2287
@hybeofficial2287 2 года назад
Its the lisp for me
@PheonixBird14
@PheonixBird14 9 лет назад
Congratulation for the video, is very well done and really helped me, but I have a question: at 2:45 you've said "colesterol backbone" (or that's what I heard, if it's me, please excuse me for bothering you)...shouldn't it have been "glycerol backbone"?
@johnmichael5135
@johnmichael5135 9 лет назад
she said "glycerol" mate. Cheers.
@beejayolorunfemi9350
@beejayolorunfemi9350 9 лет назад
It actually sounds like cholesterol..but I'd want to assume she said glycerol..since we all know it's a triglycerol head. End of story.
@d.p3540
@d.p3540 5 лет назад
so how does eating fat give you high cholesterol?
@angy2950
@angy2950 4 года назад
I love this
@israrkarim65
@israrkarim65 6 лет назад
The voice will lead me do my phD in Biochemistry. :p
@fmn2628
@fmn2628 4 года назад
The fret, very suggestive
@FrozenVodka1
@FrozenVodka1 3 года назад
that was a ton on information
@bonmec101
@bonmec101 9 лет назад
Beautiful voice!
@cara.bella15
@cara.bella15 8 месяцев назад
Best video
@adarshvenugopal8981
@adarshvenugopal8981 7 лет назад
Great content. But your voice is damn good ,maybe too good that it seems to bother certain other paracortical Areas other than hippocampus . other than that great work .hats off
@RoverT65536
@RoverT65536 6 лет назад
This video missed digestion of medium chain and shorter fatty acids through the portal vein and is perhaps using a restricted definition of what is "fat".
@lethabonkadimeng3273
@lethabonkadimeng3273 4 года назад
I confuse this pathway with that of re-esterification😭 as the chylomicrons are transferred to the lacteals enter the lymphatics, not the portal vein😭😭 (in monogastrics)
@froggyaddicted1522
@froggyaddicted1522 4 года назад
mlas la nk test mlm ni
@Abominatrix650
@Abominatrix650 6 лет назад
What is that weird, unearthly groaning sound playing over the title card?
@user-dq4gl1vt9f
@user-dq4gl1vt9f 7 лет назад
IS
@ma7cr1ada7
@ma7cr1ada7 6 лет назад
is this?
@aniketshad
@aniketshad 5 лет назад
Amazing voice....❤️
@MelbourneMaster
@MelbourneMaster 4 года назад
*Some points you missed* Remember fatty acids dont simply diffuse into enterocytes in the intestine. They are absorped by *facilitated diffusion* , they are assisted by FABPs (fatty acid binding proteins) located at the enterocyte membrane. Another factor aiding the diffusion gradient/ translocation of fatty acids and monoacylglycerols from the micells and into the enterocyte is the rapid re-esterification of long-chain-fatty-acids into 2-MAG into triacylglycerols already happening inside the enterocyte (completed by the enzyme acyl-CoA-cholesterol acyltransferase, ACAT). Speaking of cholesterol, cholesterol also associates within micelles and are similarily absorbed by a different *sterol* -carrying protein in the enterocyte membrane. However much less cholesterol is absorbed this way (about 40% compared to 90% in fatty acids and MAGs), this is because cholesterol is reabsorped in the ileum together with bileacids in a salvaging hepatic circulation system designed for the liver to re-use cholesterol in the making of bileacid.
@CitriReg
@CitriReg 4 года назад
congrats mate you want a trophy
@MelbourneMaster
@MelbourneMaster 4 года назад
@@CitriReg What a strange comment. His videos are meant for education. It is only fitting for health professionals watching to add to the level of sophistication so that viewers can aid each other in learning the topics that are presented.
@Karenqay
@Karenqay 4 года назад
Would’ve been nice if it was detailed from mouth to rectum rather than just explaining the breakdown that occurs in the small intestines
@uctuyentran2253
@uctuyentran2253 7 лет назад
The voice is really bland giọng nói thật dễ thương
@sadeema1942
@sadeema1942 8 лет назад
6:14 What even.
@poggernation
@poggernation 7 месяцев назад
Mac Man?
@annatomasova8477
@annatomasova8477 3 года назад
❤️❤️❤️
@ayasamer7731
@ayasamer7731 3 года назад
I really wanna huge u after seeing ur explanation cause I understand perfectly from u ❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤😻 I'm going to complete this huge great explanation in the 2nd video 🚶‍♀️🚶‍♀️🚶‍♀️🚶‍♀️
@Moss9100
@Moss9100 8 лет назад
Why cheese out of all food really
@matthew_bang
@matthew_bang 4 года назад
Who's macman
@fmn2628
@fmn2628 4 года назад
Its pac-mans brother who eats a lot of Big Macs
@snowlynx1585
@snowlynx1585 4 года назад
Wait so there are chylomicrons in your lungs?
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