Doctor explains HOW TO TAKE ALLOPURINOL (Zyloric / Zyloprim) for GOUT | + common doses, side effects

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In this video Doctor O'Donovan explains key facts you need to know about a medication called ALLOPURINOL (also known as Zyloric, Uricto or Zyloprim) and how it is used to treat a condition called GOUT - where uric acid crystals build up in the joints.
In the video we cover:
1. What is allopurinol? (0.43s)
2. Who can and can't take it (1.16s)
3. How to take it (1.49s)
4. Side effects (3.24s)
5. Advice if pregnant (5.43s)
6. Taking it with other medications (6.13s)
Key facts from the NHS:
*Allopurinol reduces the amount of uric acid made by your body's cells. *This reduces symptoms such as swollen and painful joints (gout).
*It may take several months before you feel the full benefit of allopurinol.
*During the first few months of treatment, as allopurinol starts to work, you may get more gout attacks. However, your doctor will prescribe non-steroidal anti-inflammatory drugs (NSAIDs) or colchicine to help with this.
*When allopurinol is taken regularly, it can lower the number of gout attacks and help prevent damage to the joints.
*Usually you will start allopurinol after an acute attack of gout has completely settled.
Further information:
www.nhs.uk/medicines/allopuri...
bnf.nice.org.uk/drugs/allopur...
www.mayoclinic.org/drugs-supp...
#doctor #gout #medication #pharmacy #health #healthcare
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Disclaimer:
The video is intended as an educational resource only. The information within this video or on this channel isn't designed to replace professional input, so if you have any medical issues please consult a medical provider. No professional relationship is being created by watching this video. Dr. O’Donovan cannot give any individual medical advice. All information should be verified for accuracy by the individual user. Dr O’Donovan accepts no responsibility for individual interpretation of data, although it is always accurate to the best of his knowledge at the time of the video being published. This is an EDUCATIONAL video. Images are used in accordance with fair use guidelines.
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Content provided via RU-vid is for general information purposes ONLY. Information videos are not produced to provide individualised medical advice. Medical education videos on Doctor O'Donovan are not a substitute for professional professional medical advice, diagnosis or treatment. NEVER ignore professional medical advice because of something you have heard here. ALWAYS consult your doctor regarding any concerns about your condition or treatment.

Опубликовано:

24 июл 2024

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Комментарии : 95

@brendangoodenough173 10 месяцев назад

I was on a number of medications for various aches and pains including Osteoarthritis and severe gout. Taking daily Allopurinol literally changed my life, it's now the only medication I need to take, no more nightmare getting moving in the morning, no general aches and pains or inflammation, and more importantly, a normal diet and no crippling flareups...

@destroyerarmor2846 7 месяцев назад

I know that pain🙏😬

@reggiepalmer6157 4 месяца назад

How long do you take it for?

@suecameron3124 10 месяцев назад

Thank you for taking your time to do this for us. What I am looking for is an explanation of what the medicine is actually going to do to my body physically, after 5 days of taking it I have had a big flare up in an effected area, this lasted a day and seems to be settling down today...

@lilacscentedfushias1852 Год назад

I did enjoy it and found it very useful, will be subscribing as you have an easy to listen to voice, concise whilst still informative:)

@DoctorODonovan Год назад

Wow, thank you for such a nice comment!

@strangetalkwithdoc3141 Год назад

Dr. O'Donovan thank you for the information

@DoctorODonovan Год назад

You are very welcome

@arsalan101 11 месяцев назад

Amazing content and very well explained. Subscribed

@DoctorODonovan 11 месяцев назад

Thank you so much

@vandajohn9128 Год назад

Thank you very much for explaining I do understand you clearly Doctor ❤

@DoctorODonovan Год назад

Great !

@jenifebungcasan8904 Год назад

Thanks doc for your explanation about allopurinol ☺️♥️

@DoctorODonovan Год назад

My pleasure

@JennyMillington-zy5li Год назад

Useful information

@DoctorODonovan Год назад

Thank you Jenny

@Daniel539BC 6 месяцев назад

Thank you Doctor 🙏🏻

@DoctorODonovan 6 месяцев назад

Most welcome!

@felicita437 2 месяца назад

Thank you Dr so much I find this video so helpful. I have a question (much more a concern) my dad is taking a 100mg alupirinol for 1 year and half (getting blood test and ALT,AST,ALT test)and and I am so worried about the side effects of this medicine on his liver in long time... Is it dangerous for liver or can this medicine cause any harms on liver? Does he need to do any other test or monitoring?

@Daniel539BC 6 месяцев назад

Hi Doctor Can you tell us about this medication? INDOCID indometacin 25 mg Thank you 🙏🏻

@reginaldchristopher9918 6 месяцев назад

Hello sir, if I need to take 200mg allopurinol, can I take two tabs altogether as "one dose" at night instead of two dose (100mg morning and evening)?

@tatteredquilt 11 месяцев назад

And, doctors/NPs/PAs- KNOW that allopurinol dosing in CKD is important. I recently found out that I'd been given an 8x overdose for 3 YEARS while having CKD-3B, which I had at the time of gout diagnosis. It was caught by a very astute new NP at my GPs office. I won't take any allopurinol now, because my kidneys are more important than dealing with a couple of days of pain when the flares hit. Yeah, those days suck- but dialysis would be worse. LOOK UP all meds you are prescribed, as well as the chronic disorders you have, to see if any medication is safe for you. Doctors tend to do "cookbook" medicine- where everybody gets the same thing. Having a bunch of specialists just means I'm a collection of separate parts, and not a whole human being.

@marsultra7032 Год назад

I'm on 100mg shall I take them together or separately?

@sobekstephanie Год назад

Thanks!

@DoctorODonovan Год назад

No problem!

@smilenowlaughlater 6 месяцев назад

what to do if there is inflammation of joints after chickengunya and steroids are not working ?

@waitang1961 Год назад

❤thank you very much

@DoctorODonovan Год назад

Thanks !

@cplai 2 месяца назад

You said Allopurinol should not be taken during a Gout flare up. My problem is that first time I started to take allopurinol, my gout flared up. Should I stop immediately or should I continue to take the second dose? I don’t know if it was due to the fact that I was like 12 hours late when taking my second dose or the dosage my doctor prescribed me was inappropriate? It seems a very tricky process to start and stop allopurinol. Can you provide more instructions regarding that?

@glorenesiarres897 5 месяцев назад

I am allergic to Allerpuro. 😢 so now do I do

@johnrutherford1650 5 месяцев назад

Cannot take this because it makes me sick so I take prednisone. Also take febuxostat Daily to stop the flag ups but does not work all the time. I try and watch what I eat but still get gout so I just about to give up. Drink plenty of water . Very frustrating!

@Thedrysurrealbloke 6 месяцев назад

I've got an underactive thyroid and been on it for a year. The doctors just upped it as well.

@reggiepalmer6157 4 месяца назад

Do you take it for thyroid issues as well?

@Thedrysurrealbloke 4 месяца назад

No just thyroid Meds

@sihammohammed2109 Месяц назад

Is Allopurinol good for aczma skins condition

@SRTHEMIMOPAR 5 месяцев назад

Can i take ibuprofen while taking this??

@anierylldcastillo5155 11 месяцев назад

My mother has a normal uric acid . However. She has tophi in her ankle and fingers. What would be that reason for her normal uric blood result

@DoctorODonovan 10 месяцев назад

Thank you so much for watching the video and taking time to leave a comment. Unfortunately (and I know this will be frustrating for you), I am unable to give individual medical advice out on this channel. This is because of medico-legal reasons, not knowing your full case, circumstances, and it would be unethical of me to do so otherwise. I have included the general resources I used to make this video in the description box but I have to advise that you speak to your own health provider (e.g. doctor, nurse) so that they can properly assess your case. This is the safest and most ethical advice I can give since this is just intended as a general educational resource. Thanks for understanding.

@tjyessir13 Год назад

I have not seen a Rheumatologist yet as I am booked in soon but my flare ups have been going on for sometime now maybe 2 months so I don’t know if it is working or not, my doctor had seen my uric acid level high but maybe I need a higher dose or I have too much built up crystals in my body and it is getting broken down.

@DoctorODonovan Год назад

I can't provide individual advice online for medico-legal reasons. Please speak to your own health provider if you have questions or concerns about your health.

@eagyinjection Год назад

How do you deal with a gout attack while you are taking allopurinol

@edwardbliss8931 Год назад

I was prescribed Colchicine with Allopurinol to prevent gout attacks. I'm not thrilled about the upset stomach it gives me, but it's either that or excruciating pain in my joints

@ZidanDua-sd2ji 3 месяца назад

Teu ngarti beggu, aing , kegunaan alupurinol naon??

@kleenslate5292 Год назад

Should a doctor run some tests for kidney/liver function before prescribing Allopurinol? The nurse practitioner of rheumatology I met this morning prescribed Allopurinol based on the fact that I had numerous gout flare-ups recently and uric acid level of 10 back in 2019. I expected some tests to be run before treatment proceeded because I haven't had a physical in about three years...surprised it wasn't. Is this common practice?

@DoctorODonovan Год назад

I am sorry but for medico-legal and ethical reasons I can't give individual clinical advice on this channel. This is designed as a general education channel. Please consult your doctor or health provider for individual questions and concerns. I hope you found the video informative nontheless. Best wishes.

@kleenslate5292 Год назад

@Craig Jones I'm obviously expecting too much from doctors, or a nurse practitioner in this case. I'm just taken aback she wanted to put me on two different medications for life without running some tests. After my encounter with her I cleaned up my diet, lost about 15 pounds and doing well so far.

@beatsmosaic Год назад

Kleen slate, I’ve had the same experience. No one tells your from young we’ve gotta figure this shit out on our own

@kleenslate5292 Год назад

@@beatsmosaic A doctor/nurse practitioner who actually gives a damn about their patient is not as common as one would expect. We have to be proactive when dealing with them you never know which one you're going to get.

@rhodorala-anan3781 3 месяца назад

Thank you dc

@dawnvaneeden2470 Год назад

Do I have to have Dr script

@DoctorODonovan Год назад

Here in the U.K. , yes

@ralphbarf773 9 месяцев назад

You didn’t mention it is a leading cause of dress syndrome, usually caused by starting with too heavy a dose before tapering up, that syndrone has a 10% fatality rated & is otherwise living hell.

@Thedrysurrealbloke 2 месяца назад

I'm on it and thyroxine for a underactive thyroid. My doctor said nothing about this.

@DoctorODonovan 2 месяца назад

Hope the video was helpful

@foolishbeat115 Месяц назад

Doc, why is it not suitable for Chinese, Thai or Korean and Persons with Thyroid Problem?

@lanskielutlut 25 дней назад

Tsungclk kekakin klungkekokok

@netkotreci3135 Год назад

Hi doctor Do I have take allopurinol for the rest of my life?

@lanskielutlut 25 дней назад

Yes even if u are gone

@georgekillian2852 2 месяца назад

I’ve had my first gout attack ever, has not gone away (lingering in big toe) does not hurt to walk anymore but when flexing big toe still feels like it’a inflamed. I have not taken allopurinol because my rheumatologist said not to take it during an attack, does this still count as an attack when it’s lingering? My podiatrist said to take allopurinol asap and I gave her my concerns that the rheumatologist said and she said to try it for a week I don’t know what to do

@georgekillian2852 2 месяца назад

Also should I stop drinking until this lingering goes away or for 6 months or what - it’s been 5 weeks no alcohol and I’m 26 so I’m definitely questioning if I can just have a beer or not.

@B-Killin Месяц назад

It is recommended to not start Allopurinol during an attack. Instead, you should be taking a steroid pack. It kills the attack. You need to reduce inflammation in your body. You are consuming shit food and need to reduce your caloric intake to combat this. I have a lot of experience in gout management. Start by reducing your daily caloric intake to 2,000 calories per day. You should lose body fat. Measure your weight while you do this. Once you stop losing, reduce your daily caloric intake by another 500 calories. You should notice you start to losing body fat again. This reduces inflammation which is what causes your attacks. Go to the frozen food section in your grocery store if you’re use to eating only fast food. Look for the blue bags by Voila! They are stove top meals of veggies, noodles, and meat. You get a lot of food with these and not overblowing your calories.

@B-Killin Месяц назад

@@georgekillian2852i admit im a drinker too. I have found that beer triggers attacks more than spirits or wine with me personally. Read my recommendation above and cut out beer. Maybe try vodka and cranberry juice. Cranberry juice is a natural anti inflammatory! Try your red wines and neat whiskeys. PS: I found that any Corona beer use to highly raise my chances of an attack.

@kokyaw237 8 месяцев назад

Let me know is there any injection for gout?

@EnigamiNetshinobi 13 дней назад

You can get a cortisone shot.

@nimapahlevan5383 6 месяцев назад

Does it soften large tophus on the toes?

@carlo1300 Год назад

So Allupurinol lowered my Uric acid from 9.5 to 4.8 and now I’ve had ankle gout for a month straight. Is this my body getting rid of the dissolved gout crystals. How do I speed this process up.

@reginaldchristopher9918 11 месяцев назад

How long is this reduction from 9.5 to 4.8? And HOW did you take allopurinol? Gout attack must use Colchicine and Allopurinol 100mg first. Unless you develop swelling, don't add NSAID.

@carlo1300 11 месяцев назад

It didn’t take long, maybe 3-4 months. But I was taking 900mgs of Allupurinol a day.

@carlo1300 11 месяцев назад

Colchicin upset my stomach so I stopped. Methylyprednilosone also stopped working for gout attacks. I’m trying to get on KRYSTEXXA TO RID my body of crystals

@reginaldchristopher9918 11 месяцев назад

@@carlo1300 or you can use Stinging Nettle tea daily and save $30k for Krystexxa or summat. I usually eat medium sized meal before consuming colchicine.

@reginaldchristopher9918 11 месяцев назад

@@carlo1300 3 to 4 months is usually alright. I don't know whats ur uric acid level, but I hope 900mg was from a diagnosed measurement.

@alanhutchison9490 7 месяцев назад

I am on 200mg, I take on in the morning and 1 at night...

@loudee3595 4 месяца назад

My biggest problem is in the past I have taken it it’s actually CAUSED gout attacks

@Bumerism 28 дней назад

Taking now for to weeks not helping

@user-xu2nv4jf9w 3 месяца назад

should i take allopurinol during the gout attack?

@SladeBling 2 месяца назад

another video said to take colcochine during an attack then take allopurinol once the attack is over.

@shyamaherath7524 9 месяцев назад

This user morning or night ..?

@lanskielutlut 25 дней назад

Afternoon

@daddyteddy85 Месяц назад

Have had a gout flare up for 6 weeks now...am in pain

@DoctorODonovan Месяц назад

I’m sorry to hear this

@B-Killin Месяц назад

Brother! Get a steroid pack! Do you not have medical insurance?

@yourentertainmenttonight9355 3 месяца назад

can Allopurinol cause Memory loss

@lanskielutlut 25 дней назад

Yes u will forget ur name

@Daniyalumer95 Месяц назад

Anyone else experienced that when you take allopurinol , it makes gout worse.. and more pain.

@B-Killin Месяц назад

No. Did you start Allopurinol during a gout attack?

@Daniyalumer95 Месяц назад

@@B-Killin no before attack

@MagicCarpetMusic 2 месяца назад

The side effects sound horrendous, totally off-putting. Is there really nothing more gentle than this to lower uric acid in the blood?

@B-Killin Месяц назад

I have been on Allopurinol for over a year with perfect results. Another alternative is reducing inflammation in the body. How? Consume less calories. Its that simple. Skip a meal a day. How many calories are you consuming per day? If its over 2,000, reduce to 2,000 or 1500. This will reduce inflammation and even make you lose some body fat

@B-Killin Месяц назад

I dont know who needs to hear this, but i have a lot of experience with gout management. I havent had an attack in over a year using Allopurinol as well as lifestyle changes. Im 6’ 230lbs. I would describe myself as chubby athletic. I train in martial arts and can average 10 minute mile jogs for four miles at a time. I drink heavily once a week and my diet is pretty poor. I have found that skipping a meal a day reduces inflammation of the body very well. Try to consume 1200-2000 calories a day while measuring those effects on your weight. My first week i lost 10 lbs by just limiting myself to a 2,000 calorie daily intake. I needed to move to 1200 calories a day after that to continue losing fat. This will greatly help reduce inflammation and help prevent gout attacks when paired with Allopurinol.