It's only annoying when you're unprepared or surrounded by a bunch of seeker. I solo'ed it yesterday, it was challenging but hella fun when I took it down by myself. I was using fully upgraded Plain armor and weapons and forgot to bring the fire res wine. My experience is make use of terrain that can cover myself from the fireball or water to cancel the effect, in the worst case: block or dodge, whichever saves the most stamina. Iron sledge to deal with the Ticks, and Draugr Fang + Neddle arrows aim for the underbelly in the small window when it spawn those Ticks.
@@shironeko3457i had some problems once because i was using the swamp chest for a seeker nest, and didnt have any fire resistance potion so i died more than 5 times trying to recover my equipment, but normally its just annoying to deal with.