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From our free online course, “Cell Biology: Mitochondria”: www.edx.org/course/cell-biolo...
Harvard Professor Rob Lue explains how mitochondrial diseases are inherited and discusses the threshold effect and its implications for mitochondrial disease inheritance.
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8 окт 2017

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Комментарии : 2 тыс.   
@HarvardOnline
@HarvardOnline 5 лет назад
Learn more in our free online course, “Cell Biology: Mitochondria”: harvardx.link/pwnt
@letsbehonest4221
@letsbehonest4221 4 года назад
I am from Australia .. May i do this course .. and how hard is the exam. .I am not an educated person, I work as a Roadie (event set up for bands and other events) but would love an opportunity to learn some thing new.
@higherresolution4490
@higherresolution4490 3 года назад
Has the animator mistakenly shown Complex II as transmembrane instead of being part of the Citric Acid Cycle in the Matrix? I love the video. Just wondering if the mistake is on my part.
@SeaJay_Oceans
@SeaJay_Oceans 3 года назад
I would say that now, a key difference between biology and technology is stability at room temperature. You can turn off a computer and turn it on weeks later and it's still works. But you can't 'shut down' a living being, and restart them weeks later - their molecules break down and degrade, too fragile.
@geraldbamberger927
@geraldbamberger927 3 года назад
Outstanding work. Thank you for this magnificent legacy, Dr. Lue.
@100nirosta
@100nirosta 2 года назад
please remove the reality under the microscope. Show the real nature, not this fictional graphics.
@LavenderTheArj
@LavenderTheArj 4 года назад
I remember when I was studying biochemistry II in my bachelor's degree, desperately looking for a video on this on the night before the final exam, didn't find one and had to memorize it the old fashioned way, all I'm saying is that what you're doing is extremely valuable for a lot of students, best of luck.
@sortof3337
@sortof3337 4 года назад
Hello, I have a question for you. There is a news about a company called Solar foods, which apparently converts C02, h20 and electricity to make single celled proteins. I am a software engineer but very disturbed by the fact that I can't find anything about this. Wouldn't it be creating life out of soup or could the be just using microorganisms?
@PriyageethKS
@PriyageethKS 4 года назад
@@sortof3337 single-celled protein🙄
@Cazy243
@Cazy243 4 года назад
@@sortof3337 There's no such thing as a single celled protein. Proteins are macromolecules made of amino acids and they make up parts of cells, but they themselves aren't cells. Maybe you meant to say that they were designing a way to synthesize simple proteins?
@2bdocvarun
@2bdocvarun 4 года назад
Was thinking the same
@rajarshigupta6207
@rajarshigupta6207 3 года назад
There are single celled proteins which are being used by astronauts for their protein requirements. It is made by microbes like spirullina They have way more protein content than meat
4 года назад
Imagine a whole biochemistry book animated like this... I wish I'd be alive till then :'(
@vblaas246
@vblaas246 4 года назад
Not a whole book, but the ibook EO Wilson's Life on Earth comes very close. Same animators. More people should get to know of it. It is great.
@LouieAblett
@LouieAblett 4 года назад
@@vblaas246 thanks so much, I've got it now and installed itunes u so I can do all the assignments. I can't believe it's free
@vblaas246
@vblaas246 4 года назад
@@LouieAblett You're very welcome :) Check pdb101 (protein data base) if you're looking for more specific background information.
@vblaas246
@vblaas246 4 года назад
@Sakurako Hikari Yes, I'm thinking at the Cardboard Demo app by google by which you rotate objects (masks and vases) by rotating your head. Create the scene with mMaya plugin and use Unity to render the scene. Have been thinking about making a website for that, must be cheap though.
@kathrinat9824
@kathrinat9824 4 года назад
@@vblaas246 hey would you know any way to get it on android
@noelsrx376
@noelsrx376 3 года назад
This is physics, chemistry and biology combined in one! And I love it!!
@hugodaniel8975
@hugodaniel8975 3 года назад
I wish there were more black, women and lgbt in science
@Hexnilium
@Hexnilium 3 года назад
I would add computer science / engineering here as well. It's functioning as a molecular machine, and starting to work with information at a computational level.
@carmenmoldoveanu4897
@carmenmoldoveanu4897 3 года назад
@@hugodaniel8975 they have first to define themselves.
@gameslayer404
@gameslayer404 2 года назад
@@Hexnilium lies
@gameslayer404
@gameslayer404 2 года назад
@@jacky9575 Cause life is better then machines and stuff, and has absolutely no correlation to it.
@killianoshaughnessy1174
@killianoshaughnessy1174 4 года назад
I am amazed at the complexity of being alive.
@kxmode
@kxmode 2 года назад
(Psalms 139:1) "O Jehovah, you have searched through me, and you know me." (Psalms 139:14) "I praise you because in an awe-inspiring way I am wonderfully made. Your works are wonderful, I know this very well." 🙂
@dr.cheeze5382
@dr.cheeze5382 2 года назад
@@kxmode ok and? no really, do you seriously think quoeting some old book full of so many contradictions and compleatly ficticuous facts is going to make me belive in a being that doesn't need to even exist to explain the universe?
@MegaBlack077
@MegaBlack077 2 года назад
​@@dr.cheeze5382 is there a reason why the redox centers are perfectly aligned clusters of different atoms?
@Haven_city_civilian
@Haven_city_civilian 2 года назад
Me too.
@casualbird7671
@casualbird7671 2 года назад
@@MegaBlack077 yes, the ones that weren't didn't survive :>
@hasen_judi
@hasen_judi 4 года назад
"and this is why we have to breath oxygen" was a mind blowing moment for me.
@denislavvladimirov4977
@denislavvladimirov4977 4 года назад
it's mind blowing how God made it friend :) He is like that... : D
@javsw.1878
@javsw.1878 4 года назад
Denislav Vladimirov dont claim god for this, it’s evolution that made us this way
@hasen_judi
@hasen_judi 4 года назад
@@javsw.1878 Sure, whatever
@maryweprin
@maryweprin 4 года назад
Perhaps God and evolution are not different. Billy
@Verspassungsschutz
@Verspassungsschutz 4 года назад
@@maryweprin which god? Vishnu? Thor? Ra?
@nickmagrick7702
@nickmagrick7702 4 года назад
the visual explanation really helps a lot.
@lilyilyily323
@lilyilyily323 2 года назад
RIP prof lue, this video is just one of many thousands of wonderfully helpful, selfless things he contributed to the world during his too-short lifetime.
@hosoiarchives4858
@hosoiarchives4858 Год назад
0:29 inner mitochondrial membrane 0:47 key role is to separate protons, inner from outer protons 1:08 ATP synthase, makes ATP. Uses proton flow to work 2:24 Complexes 1, 3 and 4 pump protons out 2:49 complexes get energy from electrons 3:18 complex 1 uses NADH and reduces it
@pasqualethene
@pasqualethene 10 месяцев назад
Thanks. Bruh no replies
@Mala-tg1lg
@Mala-tg1lg 16 дней назад
Thanks
@absbi0000
@absbi0000 23 часа назад
Beautiful, thank you.
@aryansaeedi7618
@aryansaeedi7618 4 года назад
My god what a beautiful video. Very clear and well explained. I’m in love with this channel.
@SachinSharma-id9kd
@SachinSharma-id9kd 4 года назад
@arin saeedi HI DEAR!
@muhammadtayab1909
@muhammadtayab1909 3 года назад
You are nice
@muhammadtayab1909
@muhammadtayab1909 3 года назад
@@SachinSharma-id9kd f
@grantfryer407
@grantfryer407 2 года назад
why you say God?
@MarceloCostaoficial
@MarceloCostaoficial 2 года назад
@@grantfryer407 HOW CAN YOU NOT? If you can't see GODs desing on that you are blind
@Roger-go6jc
@Roger-go6jc Год назад
This is just awesome. I'm 69 now and still doing paediatric nursing, but started my career in Pathology. I remember pawing through my Biochemistry text to sit exams and trying to memorise the Krebs Cycle, which is all part of this. But the process I did on a page that showed chemical energy utilised for cellular respiration has just blown right off the page. This visual takes me into a Mitochondria and starts to put the cycle into a visual sense. What a wonderful progression in knowledge we have. Now lets not forget who we are and what a beautiful planet we have.
@NewWesternFront
@NewWesternFront Год назад
who are we
@comamiday462
@comamiday462 2 месяца назад
lol u may now at least something @@NewWesternFront
@vedantbhardwaj7582
@vedantbhardwaj7582 4 месяца назад
I'm a medical student at King's College London, and honestly this has helped me sooo much with actually being able to visualise how Oxidative Respiration actually occurs! Thanks!!!!!!!!
@prernakumari7273
@prernakumari7273 4 месяца назад
Medical student also study botany..?
@vedantbhardwaj7582
@vedantbhardwaj7582 4 месяца назад
@@prernakumari7273 this type of process is also what happens in human/animal cells, so it is something we cover in medical sciences.
@hridyansh-san5270
@hridyansh-san5270 5 дней назад
​@@prernakumari7273 why are you stupid? This happens in all eukaryotic cells containing mitochondria!!
@Lisargarza
@Lisargarza 2 года назад
Learned all this stuff in grad school 40 years ago, but it was more like a concept, a chemical formula written on a page. To see it spring to life as an animated video is astounding. Thanks for posting.
@prestonburton8504
@prestonburton8504 4 месяца назад
i was simply struggling to get through it - and i hated it. but it was still something i wanted to learn later as it was a void. He found a way that i could visualize and understand it. This is teaching!
@umu-i-d2785
@umu-i-d2785 4 года назад
This happens a few Trillion times a second in our bodies. No big deal!
@mikkirefur
@mikkirefur 4 года назад
Nope, not for a loving intelligent creator - but people prefer to listen to the darkness of the enemy and deny the existence of the engineer of life. ridiculous.
@elbretto6062
@elbretto6062 4 года назад
@@mikkirefur what
@koaoi9172
@koaoi9172 4 года назад
@@mikkirefur how many shrooms did you ingest
@jtktomb8598
@jtktomb8598 4 года назад
@@mikkirefur u okay ? having visions ?
@jacobkudrowich
@jacobkudrowich 4 года назад
@@mikkirefur insane how you can see this and take it as proof of your god
@makaylamoore8831
@makaylamoore8831 4 года назад
Such a great, clear explanation! Videos like this remind me why I love biology so much. Life is amazing.
@antoniodimaggio5658
@antoniodimaggio5658 4 года назад
i was about to write the same thing!
@audreya7543
@audreya7543 9 дней назад
This is easily the most clear-cut and visually useful aid I could find online to look at the ETC complexes 1-4. I can't thank you enough for this resource!
@raplopez4258
@raplopez4258 2 года назад
What makes this video stand out is not just the breaks, but the respect for the student, BY GIVING US 5-30 SECOND BREAKS TO JUST RELAX THE BRAIN!!!! (*Cough to all you other science videos/teachers out there cough cough*)
@matthewmayorga2855
@matthewmayorga2855 5 лет назад
This is the best visual explanation of the ETS I have seen on youtube
@mindyourbussines8698
@mindyourbussines8698 3 года назад
Enfermedad de transmisión sexual.
@mrkoelle
@mrkoelle 2 года назад
Agree
@Bananappleboy
@Bananappleboy 2 года назад
@@mindyourbussines8698 why
@mikethespike056
@mikethespike056 2 года назад
@@mindyourbussines8698 SIII JAJAJ
@ectogamut
@ectogamut 4 года назад
5:19 The shark tooth ghosts show up, get their eyeballs, and leave.
@Biliana_Stanimirova
@Biliana_Stanimirova 4 года назад
I am not the only one thinking the same. The shark tooth ghost is my spirit animal! :D Its so little and cute
@COUNTERSTRICKGAME
@COUNTERSTRICKGAME 4 года назад
What 😂
@uzaysezen7319
@uzaysezen7319 4 года назад
nice one!!!!! :) :) :)
@benjaminfranklin5137
@benjaminfranklin5137 4 года назад
@@Biliana_Stanimirova don't get it
@blazednlovinit
@blazednlovinit 4 года назад
@@Biliana_Stanimirova * Pacman Will Remember This ( ? )
@yvonnemoreno8805
@yvonnemoreno8805 3 года назад
This is amazing. It puts all these concepts we're inundated with and makes it more clear. As a visual learner, I wish there were more animated videos like this!
@Ronin777z
@Ronin777z 3 года назад
The animation was incredibly helpful in understanding the material. My mind tends to wander during lessons so the visual aspect was immensely helpful.
@peterschmidt1453
@peterschmidt1453 3 года назад
We can thank Drew Berry for pioneering the animation of this invisible world, his ability to visualise these subatomic processes has made these animations possible.
@lucachirico4183
@lucachirico4183 2 года назад
I watched this video 3 years ago for the First time, when I was studying biochemistry for the exam of the bacheloor degree. Now I've just re-watched it to review the topic at all for work, and it's gorgeous like ever. I think immagines and videos can teach better then thousand of a book's pages. Colours and animations are for me the best way to rember and put every feature in our brain.
@jayski9410
@jayski9410 3 года назад
I wish we could have had visualizations like this back when I was a pre-med student in the 1970's. All we had were acronyms, arrows, and line drawings. The best analogy I can come up with is a wrist watch - in my day we could look at the watch face but just read about what made the hands go around; this animation is like opening up the back of the watch and finally seeing all the gears and springs in action.
@dielaughing73
@dielaughing73 2 года назад
I studied this stuff in the 90s and the technology had barely progressed. I am in awe at what has been achieved since then. This is very, very important work.
@edehc
@edehc 2 года назад
INSANE IN THE MEMBRANE! AND ALL OF THIS IS HELD TOGETHER BY DIFFERENCES IN ELECTRICAL CHARGES? JUST WOW…
@jesusmiguelalvarezfernande8761
@jesusmiguelalvarezfernande8761 2 года назад
Just the opposite of what happens during photosynthesis in chloroplasts. What a wonderful balance!
@NewWesternFront
@NewWesternFront Год назад
we are the plants. the plants are we. forward backward with the trees. vroom skeet skloom dbbdhfjskkdf
@geofractal
@geofractal 4 года назад
This is incredibly amazing. It is also amazing that humans can figure this out -- very smart humans, that is.
@turquoisecoleman6006
@turquoisecoleman6006 4 года назад
Geo Fractal well it's more like 'The Apple doesn't fall far from the Tree ' . (of life) ... right ? if you get me .? 🤗
@larscp
@larscp 3 года назад
Compare to the nature, then we are still monkeys
@bili4591
@bili4591 2 года назад
That’s more amazing than the fact that human can figure this out. Its impossible to build this for any human this is the creation
@maxjurish2589
@maxjurish2589 Год назад
Very smart God, that is!
@brandon-pz2ye
@brandon-pz2ye Год назад
Can figure it out but also immediatly forget all of it when talking about profitable things like cancer, diabetes, heart disease.
@amira6405
@amira6405 Год назад
I just clicked on this video. 10 seconds in and I am welcomed by a voice I recognize. The voice of a fellow Jamaican (RIP to Robert Lue). It's so surreal how just a voice can connect you to someone and now to a video I am wholly excited to watch and learn from.
@rachelchristiansen9218
@rachelchristiansen9218 4 года назад
I was literally feeling so screwed over my biochem exam because i could NOT grasp this concept. This was so clear and easily explained and I feel way more confident going into my test, and better yet it was INTERESTING and easy to continue to watch. Thanks!!
@XFz2nLDWo73x95
@XFz2nLDWo73x95 2 года назад
Did you pass? lol
@sunilnale
@sunilnale Год назад
@@XFz2nLDWo73x95 Hope So 🙃
@saysHotdogs
@saysHotdogs Год назад
@@sunilnale we still waiting
@user-pt8zt8ip3b
@user-pt8zt8ip3b 10 месяцев назад
Như trên 🤩
@divinephanes
@divinephanes 3 года назад
I remember seeing this in my first year bio class, it blew my mind when I first saw it and it still does. Thank you for this!
@fabiobarreiro
@fabiobarreiro 5 дней назад
It's almost unbelievable how complex and precise life is. A lot of hard work to keep us alive.
@TommyTumma
@TommyTumma 4 месяца назад
Professor Lue’s microbiology course at Harvard was really easy to understand. The hallmark of a great teacher. I recommend taking his full online class for free!
@judas611
@judas611 Месяц назад
How do I find this course? Do you have a link?
@andychow5509
@andychow5509 4 года назад
Wow. Amazing how much progress and knowledge we are starting to have access to. Never saw anything like this when I was growing up.
@kritikathakur5895
@kritikathakur5895 3 года назад
We want animations like this really. They helps us to have a deep insight in the topics. Thanks
@SoirEkim
@SoirEkim 4 года назад
I may not be fully aware of what it took to put this information together. Yet, I love learning in this way and the visuals are mesmerizing. Therefore I would willingly watch several days worth of videos like this. Excellent! Thank you.
@PheedPhil
@PheedPhil 2 года назад
Great video. Haven't seen a better animation anywhere else. And very accurate too, with the exception of one small detail (which most text books also get wrong). FADH2 is not the electron donor to complex II, it is physically attached to the first protein of the complex (a flavoprotein). Succinate is the electron donor (CII is called succinate dehydrogenase) and CII oxidizes it to fumarate in the Krebs cycle, passing the electrons to it's FAD, and onward into the complex.
@vitoria96634
@vitoria96634 Год назад
It's amazing you have such knowledge :D glad to know!
@sunilnale
@sunilnale Год назад
@@vitoria96634 Do You Difference between NADPH and NADH. Similarly between FADH and FADH2. my textbook is Using them alternatively... 😑
@AnuragTarmaster
@AnuragTarmaster 8 месяцев назад
@@sunilnale Sorry this is 6 months late but to answer your question they are just two different electron carriers. For every NADH the electron transport chain can produce 2.5 ATP, whereas for every FADH2 the ETC can produce 1.5 ATP. Like @PheedPhil said, succinate dehydrogenase catalyzes the reduction of FAD whereas isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase, and malate dehydrogenase catalyze the reduction of NAD+ in the citric acid cycle.
@sunilnale
@sunilnale 8 месяцев назад
@@AnuragTarmaster Thanks... I am Still Giving Same Exam... Thanks for Explaltion... Have a Good Day/ Night... ☺️
@igoralencar4817
@igoralencar4817 4 года назад
This is so beautiful. I've been looking at it for five hours.
@rolandoe.diazolivom.d.4777
@rolandoe.diazolivom.d.4777 4 года назад
Congratulations for this excellent video. Next up, please: The microscopic machinery of the outer mitochondrial membrane. This is the gatekeeper preventing a massive influx of H+ and other cations in the surrounding matrix from entering the inner mitochondrial matrix.
@trainerbrock2428
@trainerbrock2428 2 года назад
Videos like this are the future of molecular biology education at all levels. Great video!!
@michaelK.3272
@michaelK.3272 Год назад
This is one of the most informative videos I have ever seen. Excellent quality. Thank you!
@ngc-ho1xd
@ngc-ho1xd 4 года назад
Life is the ultimate Rube Goldberg machine, that in essence performs a task very similar to Maxwell's deamon. It's so beautiful!
@ffghjj9996
@ffghjj9996 4 года назад
ngc 4594 found paul davies youtube account
@lenn939
@lenn939 4 года назад
Nothing in humans violates the second law of thermodynamics.
@greggrobinson5116
@greggrobinson5116 2 года назад
Seeing this chemistry written out as reactions is impressive enough, but seeing it animated is just astonishing! And to think that this is going on effortlessly in every one of our cells all the time is downright religious.
@theSilentPsycho
@theSilentPsycho День назад
Thank you for creating this video. As a software engineer, I've always been intrigued by understanding the intricacies of how things operate on a smaller scale. Your video also highlights how we often operate in our professional lives akin to machines, much like the mitochondria units showcased, and how this can sometimes obscure our awareness of the broader universe to which we belong. It serves as a reminder that we each have a unique purpose within this vast ecosystem.
@maryamfazal3180
@maryamfazal3180 2 года назад
No other video could convey the concept that this video has conveyed. Best video ever, I'll never forget ETC ever again.
@dickmorhead6165
@dickmorhead6165 4 года назад
I have my mother's eyes and my mother's mitochondria.
@peacenow42
@peacenow42 4 года назад
Moms share like that.
@rutvin8763
@rutvin8763 3 года назад
@Sumanoharam Jha "X has their mother's eyes" is a common expression. Ask before going on a pointless rant.
@rutvin8763
@rutvin8763 3 года назад
@Sumanoharam Jha Yes, it was; dumb comments need addressing.
@stephenarmiger8343
@stephenarmiger8343 2 года назад
Reading Brian Greene’s book, Until the End of Time. He does an admirable job explaining this. I appreciate this attempt to help us understand the situation in three dimensions!
@jadhavaniket100
@jadhavaniket100 2 года назад
I was searching for a perfect explanation for the ETC and couldn't find any. Came to RU-vid and saw your video and was blown away. Thank you so much. It shows that it has taken immense efforts to create this amazing video. Thank you once again..
@MrZooganopolos
@MrZooganopolos 3 года назад
That was a lovely and descriptive review! Thanks for taking the time to make such a great video!
@xinchen3547
@xinchen3547 3 года назад
Respect to the masterpiece of the Creator, and the marvelous job of the makers of this video.
@cynthiaalbrecht3248
@cynthiaalbrecht3248 2 года назад
That is what leaps out at me, that this degree of complexity, not to mention the homochirality of the sugars and amino-acids, points to Creation by means of technology far more advanced than that employed by humans.
@leonardsipula1063
@leonardsipula1063 2 года назад
@Hemlock Cocktail Archeology is based on Science. Archaeology has proved more than 50 people from the bible to be real. EVIDENCE IS THERE YOU JUST HAVEN'T LOOKED FOR IT.
@davidtompkins5000
@davidtompkins5000 2 года назад
@Hemlock Cocktail Xin Chen was indicating that the electron transfer chain is evidence of design. The video narrator himself remarks twice the similarity to power plants. Those are designed by engineers. A consistent interpretation of the mitochondrial process would be that it was engineered. That's the argument.
@nikitasid4947
@nikitasid4947 4 года назад
That feeling when you read an offline paper book on Mitochondria and then RU-vid recommends you this.
@blazednlovinit
@blazednlovinit 4 года назад
It's okay, youtube just enjoys listening to you breathe at night.
@Bman-1970
@Bman-1970 3 года назад
Your household appliances hooked into the internet may have suggested it.
@anushkapande2085
@anushkapande2085 2 года назад
@@blazednlovinit that sounds oddly threatening im terrified
@brilwiljeff
@brilwiljeff 4 года назад
Endlessly fascinating. This self organizing system evolved from random chemical reactions into bizarre and complicated organic machines so small we hardly know they are even there.
@samp-w7439
@samp-w7439 2 года назад
The fact that this is constantly going on in our bodies is insane. The fact that people have somehow figured out all the details and intricacies of this tiny and complicated processes is on a whole other level!
@fzka_
@fzka_ 4 года назад
This is such a good visual explanation. Thanks!
@AyeshMedic
@AyeshMedic 2 года назад
This was Amazing!!! The most distinct video of it's type. I was having so much trouble in ETC and here it is in such an easy way. Good Job.
@iainmacdonald8379
@iainmacdonald8379 4 года назад
I'm reading The Vital Question by Nick Lane and this video really helped me to understand respiration, particularly redox. Fantastic book, by the way.
@Mighty_Deeds
@Mighty_Deeds 2 года назад
God's craftsmanship. A design of perfection.
@dear_imran
@dear_imran 2 года назад
Perfection Literally fall apart by goin into water/ space / fire 😒
@Mighty_Deeds
@Mighty_Deeds 2 года назад
@@dear_imran Can you do better?
@IzzytMe
@IzzytMe 2 года назад
So I can actually harness quantum energy in each cell of my body, simply by breathing oxygen and my teacher said I'm no good at physics. That can't be right!
@michaelrobinson9952
@michaelrobinson9952 Месяц назад
The line between the three big scientific disciplines becomes blurred here, wonderful.
@user-gn3sy7mq6w
@user-gn3sy7mq6w 2 года назад
This is extremely helpful for me !!!!!!! Super grateful for the master piece that you produced !
@mingngyt
@mingngyt 4 года назад
This was beautiful. amazing music and lesson.
@saisasori1073
@saisasori1073 4 года назад
Yes Ming ning ding,ho chi new, ho Lee 🐮
@iwantafreetrial7611
@iwantafreetrial7611 4 года назад
@@saisasori1073 wtf
@chetan6984
@chetan6984 3 года назад
@@iwantafreetrial7611 ming ping chow pee lee✊🏼✊🏼
@myblueparadise5807
@myblueparadise5807 Год назад
This is the best animation I've seen so far....I just have no words to appreciate you❤
@abhinabachakraborty7207
@abhinabachakraborty7207 3 года назад
Dont have words to appreciate enough how beautifully this video has been made 🥰
@danteseluvathingal5292
@danteseluvathingal5292 5 лет назад
That was amazing.thanku soo much
@rodneywar
@rodneywar 4 года назад
Thank you for sharing this highly educational video.
@kirschkern8260
@kirschkern8260 4 года назад
Amazing, you tube is the biggest Libraru or best University/school. Sad they will block or bann it. They try to make it payable.
@snowwhite2038
@snowwhite2038 3 года назад
@@kirschkern8260 seriously....... Why don't they want poor people to get educated for free
@fantaxtick9482
@fantaxtick9482 2 года назад
The most amazing thing about this is that all this came into being all by itself. Wow
@AbuQamari
@AbuQamari 2 года назад
Maybe the reason why it amazes you is because of how irrational that idea is
@JosiahFickinger
@JosiahFickinger 2 года назад
@@AbuQamari Yeah!
@JosiahFickinger
@JosiahFickinger 2 года назад
Don't be pulled into the Naturalistic worldview! You'll be decieved into ideas that are greatly irrational against Believers.
@JosiahFickinger
@JosiahFickinger 2 года назад
It takes blind faith to believe complex systems of complex systems of complex systems evolved from a blind purpose without a creator God!
@johnathanh9369
@johnathanh9369 2 года назад
I start off watching videos then I dig into the textbook so then I can imagine it. This allows me to memorize and understand it better.
@kaukabbhatti1661
@kaukabbhatti1661 3 года назад
To be honest, this is the best animation I have seen on this subject.
@lenz5362
@lenz5362 3 года назад
fr fr
@denisa.6793
@denisa.6793 4 года назад
oh my god, i praise the author, incredibly helpful
@mikkirefur
@mikkirefur 4 года назад
The author of course is the Lord God in heaven above. Clearly our current understanding of biology has proven life is designed.
@RetrogradeBeats
@RetrogradeBeats 4 года назад
Mikki Refur no
@pigeonlove
@pigeonlove 4 года назад
@@mikkirefur evolution, trial and error, chance mutations and adaptions, not gods
@peacenow42
@peacenow42 4 года назад
I praise everyone this is the most intellectually cognizant conversations ever on RU-vid comments maybe.
@zhou_sei
@zhou_sei 4 года назад
@@mikkirefur that's not what i take away from it. actually, the more i learn, the less i believe in an invisible magic wand-waver in the sky.
@lorrainecamilly7354
@lorrainecamilly7354 2 года назад
É um dos melhores vídeos sobre o assunto que eu vi, muito didático. Excelente!
@aylinm5439
@aylinm5439 Год назад
I love how he stops occasionally, so the knowledge sinks in. Thank you so much, helped alot.
@rcarmisin3465
@rcarmisin3465 4 года назад
I got so lost watching this video, it was 20 minutes later until i realized i was staring at the wall. lol :)
@fotoflo
@fotoflo 4 года назад
4:26 - "a small amount of energy is released each time an electron is passed between redux centers" -- in what form is the energy released and stored?
@switchthechannel6317
@switchthechannel6317 4 года назад
Complex 1?
@AlecPerkey
@AlecPerkey 4 года назад
as i understand, its a physical conformation change of the protein (depending on which point the electron currently is) which allows movement or "pumping" of the protons into the intermembrane space. So the energy is stored via in the pH (electrical) gradient difference on either side of the membrane. I don't think Randy's answer of 'photons' is right, the electron isn't changing energy states, its just moving along different atoms on a transmembrane protein ending up on the other side of the membrane, changing pH see en.wikipedia.org/wiki/Chemiosmosis#In_mitochondria and en.wikipedia.org/wiki/Oxidative_phosphorylation#Electron_and_proton_transfer_molecules
@marijnstollenga1601
@marijnstollenga1601 4 года назад
Basically in kinetic energy in the protein complex, that then somehow pumps protons to the other size of the membrane. The energy is then stored essentially in the higher electron potential between the membrane and is harnessed by allowing the electrons to flow and create ATP. ATP is the final power storage that is essentially used everywhere in the body.
@May4thbwithu
@May4thbwithu 4 года назад
Look up the photoelectric effect first demonstrated by Einstein I believe.
@goku21youtub
@goku21youtub 4 года назад
@@marijnstollenga1601 the right answer , people who try to solve this with physics will get nowhere, but ,its not really kinetic energy either the molecule gets reconfigured
@evanquinn6092
@evanquinn6092 4 года назад
This was an amazing video, you didn’t skip info and make it confusing thank you
@apothecurio
@apothecurio Год назад
The jump from atomic particles make a thing that is deemed as a system that sustains itself had always fascinated me and ,as a lowly layman, found it hard to actually find where I could find that info. This is the perfect start. Amazing.
@howtogaintime739
@howtogaintime739 4 года назад
What a beautiful little world, wish I could see it up close.
@turquoisecoleman6006
@turquoisecoleman6006 4 года назад
HowToGainTime Well you get to Experience it !! Which is even better . of course some would have to be done in Slow Mo !! 😜
@TheLoucM
@TheLoucM 4 года назад
Thats the weirdest part to me... because if you were to shrink enough too try too see it up close, you wouldnt see anything, because atoms and molecules are almost entirely empty and dont really emit or reflect photons at this scale (only emits photons when an electron loses energy). Add to that that we see by having photons reflecting on surfaces. We basically see our world only because of the scale at which we operate as an organism. In short, at this molecular scale, ''seeing'' means nothing. Animations like this is basically just like seeing the real thing for us hoomans, as its the only way for us to be able to interpret it and see it as something we can make sens of... if that makes sens ?
@rafiqshah2022
@rafiqshah2022 3 года назад
Become antman
@howtogaintime739
@howtogaintime739 3 года назад
@@rafiqshah2022 I dont want to become mediocrity
@MichaelBethel
@MichaelBethel 2 года назад
This really amplifies the words of the Psalmist when he says "I will praise You, for I am fearfully and wonderfully made; Marvelous are Your works, and that my soul knows very well." Psalm 139:14
@JosiahFickinger
@JosiahFickinger 2 года назад
Sorry, my reply was removed. Check out Is Genesis History? I know you'll enjoy that since you're obviously a Young Earth Creationist.
@JosiahFickinger
@JosiahFickinger 2 года назад
It's more about Christian science and Biblical verification than radical defensive talks given all the time by AIG. I stopped watching them because they were getting repetitive.
@BPLeroyLotusEvora
@BPLeroyLotusEvora 3 года назад
Absolutely fantastic educational video about the mechanisms of mitochondrial energy production!
@letsgo4834
@letsgo4834 2 года назад
Beautiful. I wish I’d had this type of material from which to learn and review years ago.
@hanadiam8910
@hanadiam8910 4 года назад
(صنع الله الذي أتقن كل شيء) سبحان الله Thank you for this very informative video!
@redemptivememelord6283
@redemptivememelord6283 3 года назад
For once I read it as "Electron transport chan" and I thought I'd meet a molecular biology waifu
@alessboo17
@alessboo17 3 года назад
HAAAHAHAHAHAHAH
@maxattacks25
@maxattacks25 Месяц назад
You might’ve seen Cells at Work already, but this reminds me of that 😂
@JohnHillEU
@JohnHillEU Год назад
Very newly interested in biochemistry and it's amazing to see the similarity in the proton concentration gradient has with the mechanisms at play in silicon transistors!
@JMYaden
@JMYaden Месяц назад
These clever animations really make this whole fascinating process come alive. Thank you! I will take your free online course!
@BramMichaelson
@BramMichaelson 4 года назад
I think I've seen all this before when I got REALLY high.
@peacenow42
@peacenow42 4 года назад
When you go back there, maybe you bring some post-its and tag some of the molecules. To say you were there.
@writer24x7
@writer24x7 4 года назад
4:26 A small amount of energy is released? Energy in what form? How the complex harnesses this energy?
@rthmjohn
@rthmjohn 4 года назад
Hands down, best video on the ETC on RU-vid.
@sangitasharma4692
@sangitasharma4692 9 месяцев назад
This is one of the best animation video i have ever seen with such a great and clear explanation
@An0nim0u5
@An0nim0u5 5 лет назад
Please can you guys make a video on Photosynthesis as well...???
@kirschkern8260
@kirschkern8260 4 года назад
Exyst somewhere for sure.
@abdulekimhuseen3971
@abdulekimhuseen3971 3 года назад
Please can you guys make a video photosynthesis as well.........?
@ashypharaoh8407
@ashypharaoh8407 Год назад
Who else is carrying out oxidative phosphorylation while watching this?
@lecturestudio4640
@lecturestudio4640 Год назад
I wish these resources were present when I was doing my graduation studies. Would have made my efforts so much more mindful and meaningful
@andrebonneau9919
@andrebonneau9919 2 года назад
I'm a physician with a bachelor's in biochemistry. Great images to transmit knowledge not just electrons.
@oleksiyalkhazov9201
@oleksiyalkhazov9201 4 года назад
Science is the best mystery and greatest magic in the multiverse
@ferid9k
@ferid9k 3 года назад
1:40 thats actually just a theory.We still dont know how atp synthase works
@servetbozdag2359
@servetbozdag2359 2 года назад
MaşaAllah Ferid. I heard that we just know one percent of the human body maybe less
@brucejohnson5786
@brucejohnson5786 3 года назад
Dude this just blew my mind. Thanks, it really clears things up
@tomorourke6301
@tomorourke6301 2 года назад
Since I've gotten Clean and Sober, this has become my all-time favorite video...feels like a Plato's mystery school subset....
@neigeepierrot4694
@neigeepierrot4694 4 года назад
Amazing this happens everyday
@goku21youtub
@goku21youtub 4 года назад
every nanosecond, trillions of times in just a single living being
@goku21youtub
@goku21youtub 4 года назад
@As It is physics= assembler chemistry/atomic and molecular level = c++ life = error doesnt compute
@mikkirefur
@mikkirefur 4 года назад
@As It is I would think, analogically speaking, both. low level super efficient machine language, and high level OO designs.
@mikkirefur
@mikkirefur 4 года назад
Thank God, literally, for that !
@Rek-55
@Rek-55 4 года назад
@As It is at old age there processes not ideal...
@rodschmidt8952
@rodschmidt8952 4 года назад
When the gradient is insufficient and the mitochondria no longer produce ATP, the cell can become starved of energy and -- become cancerous? Are not small amounts (~5%) of ATP always produced elsewhere in the cell by fermentation?
@jamesralston5293
@jamesralston5293 4 года назад
Death occurs
@demonking86420
@demonking86420 4 года назад
Depends on the organism. Some organisms aren't facultative anaerobes.
@kirschkern8260
@kirschkern8260 4 года назад
I also though on cancer. But maybe it shows other results or symptoms.
@kirschkern8260
@kirschkern8260 4 года назад
I heared omega 3 fat or faty acids are importsnt to kerp the Membrane strong. Anf the industrial fats in cookies are destroyinh the Membrane. Making the Metochondria "leaking" Protond. So it produce less Energy ir get useless at all.
@jamesralston5293
@jamesralston5293 4 года назад
@@kirschkern8260 it is now thought that this weakening of the membrane is the root cause of diabetes
@nsbd90now
@nsbd90now Год назад
I like biology and I really like modern animations of biological processes. Absolutely amazing! I subscribed.
@Bitmaker64
@Bitmaker64 3 года назад
Who else just likes to see this animations.
@ElectricityTaster
@ElectricityTaster 4 года назад
ahh yes, the powerplant of the cell.
@blazednlovinit
@blazednlovinit 4 года назад
That's one of those sound bites that will always follow these little creatures/organelles around, like whenever I watch something talking about black holes, I'm waiting for the words "not even light" to crop up.
@kalldr6355
@kalldr6355 2 года назад
Thank you so much for this, you're saving lives out here
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