Dr. Eric Ruderman of Northwestern University and Dr. Arthur Kavanaugh of University of California, San Diego look at the latest developments in psoriatic arthritis for rheumatologists
Thank you so much for this work. My Achilles is so stiff that my ROM is deteriorating which led to the purchase and use of a cane for stability and assistance in walking. At 48 it’s important that I know the disease process and can work with my rheumatologist on appropriate treatment. My rheumatologist diagnosed enthesitis and is considering an additional biologic treatment to Cosentyx.
I am HLA B27 +. I have been on Rivoq x1 yr. I am 51 and very active, exercise daily(run, cardio, free weight HIIT exercises). I have to rotate my workouts because without fail, a joint will flare. Currently, it’s my elbow after increasing my free weight to 12lbs. I’be never been able to explain to anyone until the past 4 years when my ortho dr did labs then sent me to Rheum.
Point well taken. Enthesopathies are where it's at !!! Most investigation of musculoskeletal pathology is arthrocentric in it's "philosophy". The earliest version of musculoskeletal regenerative medicine dating to the 1950's is prolotherapy. The targets for successful treatment outcomes in prolotherapy are almost universally enthesopathic attachment sites. For some reason , I wonder if you can shed light on, is that mid-substance targets aren't really part of the injection lore. It might be that immune activation of of the entheses induces repair at mid-substance targets or perhaps chronic lesions go bad at the entheses whereas catastrophic failure from rapid high force injuries are more likely to occur at the mid-substance regions. Any thoughts??
How you achieved that? I'm recently diagnosed with psoriatic arthritis and peripheral neuropathy. Also have scalp psoriasis. Enthesitis is affecting my right foot very hard.