To set up vendors for items in D365 F&O so they appear in purchase requisition lines, first create the vendors and items in the system. Then, assign the vendors to the items using the Approved Vendor List under the Purchase tab in the item's details. Configure the Procurement and Sourcing Parameters to allow vendor selection in purchase requisitions. When creating a purchase requisition, the linked vendors will be available for selection.
A question, how to work with partial purchase requests. Example: I make a purchase request for 50 lines but I have a supplier who answers me with 5 lines and I want to place the Purchase Order for those 5 lines while I am still waiting for the response from the other suppliers for the other 45 lines.