First year path resident here, thank you so much for these. I've been looking for easy to digest histology videos to help familiarize myself under the scope and these have been so great. Please please make more for each organ system.
I know this isn't geared towards me because I'm MS1 but I was curious. So this may be a stupid question, but the defining characteristic of adenocarcinoma is the fact that it invades glands ? While the scc's characteristic is the the prolific dysplasia of cells and whether or not it then invades vascular structures ?
Not a specialist of any kind in the matter, but these terms don't refer to invasion but rather refer to tissue differentiation. Adenocarcinomas (ADK) come from glandular tissue or present characteristics of glandular tissue (the cancer itself forms glands). SCC's come from epithelial/squamous cells. This is why SCC is present where there is presence of epithelium (ENT, esophagus, skin, cervix) and ADK is more present where there are glands (distal esophagus, stomach, colon, breast)
Hi, I'm sorry if my video confused you. I totally agree with @Marc-Antoine Lalonde! Defining characteristic of adenomacarcinoma, SCC, all epithelial carcinomas is the presence of invasion past the basement membrane. Lumen formation is a characterized of glandular differentiation.
