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Exploring bias in forensic DNA profiling | Dan Krane | TEDxDayton 

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This talk was given at a local TEDx event, produced independently of the TED Conferences. The science of DNA profiling is sound, but much of what passes as DNA profiling is not scientific. Many testing labs resist interpreting evidence samples without having knowledge of a suspect's reference DNA profile. Blind interpretation of test results is possible and would greatly increase the reliability of the statistical weights given to DNA profile matches in some cases.
Dan is a professor in the Department of Biological Sciences at Wright State University where he has been a faculty member since 1993 and where he currently serves as the President of the Faculty. He graduated with a Bachelor’s degree for a double major in Biology and Chemistry from John Carroll University, and a Ph.D. in Biochemistry from the Cell and Molecular Biology Department at the Pennsylvania State University in 1990. Dan is also the president and a co-founder of Forensic Bioinformatic Services Inc., where he has overseen the development and implementation of software designed to automatically and objectively review STR DNA testing results.
About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)

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27 июн 2024

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Комментарии : 30   
@RosannaMiller
@RosannaMiller 6 лет назад
You're brilliant! Thank God for at least one objective man in there, fighting for good.
@sr69511
@sr69511 9 лет назад
I would love if there was a transcript for this talk. It got a bit confusing at times.
@Treblaine
@Treblaine 4 года назад
Next to where the "like" buttons and share and "save" buttons below this video, to the right of all of those is a ". . . " click on that and you'll get a dropdown menu where you can open the transcript.
@irishgirl1519
@irishgirl1519 8 лет назад
Great informative video !
@333thelc
@333thelc 7 месяцев назад
Thank you, amazing talk! Very easy to understand
@a1milan708
@a1milan708 Год назад
voor de mensen die deze video moeten kijken voor engels dt is het antwoord: a= 2e bolletje b= 2e bolletje c= 1e vakje, 4e vakje en laatste vakje d= 2e bolletje
@Jack61
@Jack61 8 лет назад
Very well explained!
@darksideofthemoon2348
@darksideofthemoon2348 Год назад
I'm 6 years late in watching this lol hey Jack 😎💕👋
@Jack61
@Jack61 Год назад
@@darksideofthemoon2348 Hey!! 💘💘
@GeneticsLessons
@GeneticsLessons 5 лет назад
Oh, these type of problems are easy to overcome - just use DNA profile kit of a different producer that is using different primers sets. Then compare again.
@krecikowi
@krecikowi 4 года назад
Exactly. Problem is that in those labs there are not many REAL scientists but many technicians... doing job. I'm molecular biologist and I would love to work on issues like this. How to get there? You know, I'm overqualified... with my PhD to get job in the lab like this...
@karthikkumard8623
@karthikkumard8623 3 года назад
@@krecikowi Your from India I think 🤣🤣😂😂
@RockerProf
@RockerProf 5 месяцев назад
Great talk!! Are those allele variations due to a different number of short tandem repeats in the alleles, or are those allele variations due to single nucleotide polymorphisms? Also, how do you know which allele comes from which parent?
@Rowgue51
@Rowgue51 Год назад
Confirmation bias is certainly a major problem in this field. But the methodology itself is highly suspect as well. Most people don't realize that they are not actually comparing a full DNA profile and that they're using the STA shortcut. It's claimed that this methodology produces a result that will only match a sample with 1 in a billion people. But there is nothing that actually supports that claim other than wild speculation. There have been exactly zero studies done on how often we actually see people with the same repeating pairs, or more aptly enough of the same repeating pairs that an analyst could make a plausible case that their profiles match.
@neallesimpson9663
@neallesimpson9663 7 лет назад
do these problems arise in electrophoresis?
@DracenaMarge
@DracenaMarge 8 лет назад
Right?
@ahmedfarooq1137
@ahmedfarooq1137 2 года назад
These issues may be resolved by following the established guidelines regarding subject.
@theforensicinstitute367
@theforensicinstitute367 2 года назад
Sorry, you are just wrong.
@tfb123
@tfb123 Год назад
What is meant by blind testing? If the question is, "Does Suspect DNA match Sample (Crime Scene) DNA?", how can it be answered without looking at the Suspect DNA? I can imagine providing multiple samples and asking, "Which of these samples matches the crime scene DNA the best". Is that what is meant by "blind"? Too bad that wasn't explained.
@Rowgue51
@Rowgue51 Год назад
Blind testing in this context would mean that the person doing the analysis would not know beforehand where any of the samples were from. If you know sample A is from the crime scene and sample B is from the suspect then you may be prone to confirmation bias when comparing the results. In theory if you don't know anything other than that you're being asked to compare two samples then it should eliminate any confirmation bias and result in a more honest evaluation of the evidence. The main problem with that theory though, is that in the context of criminal investigations the lab is always going to know that they are comparing a crime scene sample to a suspect sample. Prosecutors don't send them samples to test for any other reason.
@falseaccusationjapan5640
@falseaccusationjapan5640 2 года назад
This is horrifying! I was forced to give a DNA sample based on a false accusation with racial undertones here in Japan. After all the charges were dropped the police insist on keeping the DNA sample in their “suspects“ database forever for future matches.
@ashishkishorchavan3766
@ashishkishorchavan3766 2 года назад
That's sad, but you can always file a case against the Japanese Government, according to the LAW.
@SarahDIrish
@SarahDIrish 10 месяцев назад
👀
@jofogarolli5379
@jofogarolli5379 3 года назад
Can somebody explain if there is No DNA against the defendant and victim can a cps and police charge them.?.rsvp
@roverbett3858
@roverbett3858 Год назад
police will still charge them to conclude the case and be labeled as heros, the so called experts r biased, and the jury is not smart enough to understand the flaws.
@victorlota9501
@victorlota9501 4 года назад
guys pls help me for this question :After watching the video, write a short paragraph on how bias can influence the DNA profiling.
@MUZKF47
@MUZKF47 Год назад
Pointless vid and I’m a molecular biologist
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