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Fighting Antibiotic Resistance with Phage Therapy 

Science Communication Lab
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Phages have been battling bacteria since the dawn of time. Evolutionary biologist Paul Turner explains how phages could be harnessed to fight the rising threat of antibiotic resistance, and it’s not what you think!
For Educators: Access free teaching resources at sciencecommuni...
~ About the Film: How to Kill a Superbug ~
Phages, the natural viral adversaries of #bacteria, have been locked in an ancient battle since the dawn of time. This relentless evolutionary struggle has taken on renewed significance in the face of antibiotic-resistant bacteria, commonly known as #superbugs. The widespread overuse and misuse of antibiotics have made antibiotic-resistant bacteria a grave global health threat.
Evolutionary biologist Paul Turner’s groundbreaking research centers on using #phagetherapy to tackle the modern challenge of antimicrobial resistance. Phage therapy works by treating bacteria, like Pseudomonas aeruginosa, with #phages. These #viruses infect the bacteria, killing most of them off, until they evolve in a way that makes them susceptible to conventional antibiotics. It’s biological trickery at its best!
This approach holds immense promise in the ongoing battle against antibiotic resistance. It not only targets specific superbugs but also addresses the risk of perpetuating further #drugresistance, a concern associated with conventional antibiotics. By utilizing phage therapy, Paul's work offers a glimpse into a future where we can outsmart and ultimately overcome the resilient superbugs that threaten public health.
#antimicrobialresistance #antibioticresistance #phage #PaulTurner #virus #microbe #microbes #microbiology
~About the Science Communication Lab~
We are a non-profit organization of scientists and filmmakers collaborating on documentaries in order to build a more scientifically-engaged society. Find out more at sciencecommuni...
~ Credits and Resources ~
Directed by Ruth Lichtman & Sharon Shattuck
For full credits and more resources, please visit the film's website at sciencecommuni...
Except where otherwise noted, this work is licensed under
creativecommons...
© 2023 Science Communication Lab™. All rights reserved.

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26 сен 2024

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Комментарии : 53   
@scicommlab
@scicommlab 10 месяцев назад
Teaching resources for educators are now available! Check them out here: sciencecommunicationlab.org/science-videos/phage-therapy/
@sheshnathbharti9783
@sheshnathbharti9783 6 месяцев назад
😊😊😊😊😊😊😊p😊😊😊😊😊😊😊0😊😊
@Sehara
@Sehara 2 месяца назад
I am suffering from osteomyelitis caused by Pseudomonas bacteria. It's in my calcaneus. Waiting for another surgery while on Cipro who is not working. It is bad. Really bad. I don't have diabetes but I did have radiation therapy a long time ago. I feel that phage is the only option for me but how to get it?
@michaeltimpanaro5622
@michaeltimpanaro5622 4 месяца назад
I remember when Bacteriophage study was just coming of age in the mid 70s in grad school! Prof talked about their potential. Great that they are now being studied for their anti bacteria properties.
@scicommlab
@scicommlab 11 месяцев назад
Related Resources: - Chan, B., Sistrom, M., Wertz, J. et al. Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa. Sci Rep 6, 26717 (2016). doi: 10.1038/srep26717 (Link: www.nature.com/articles/srep26717) - Kortright KE, Chan BK, Koff JL, Turner PE. Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria. Cell Host Microbe. 2019 Feb 13;25(2):219-232. doi: 10.1016/j.chom.2019.01.014. (Link: doi.org/10.1016/j.chom.2019.01.014)
@scicommlab
@scicommlab 11 месяцев назад
Thank you all for joining us for our World Premiere today! If you enjoyed this film, make sure to join us for the premiere of our next film in the series about Electric Microbes on November 2nd at 1pm ET | 10am PT: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-cXARtgRHFsM.html
@seanchristiansen4982
@seanchristiansen4982 13 дней назад
Shout out to Dr. Pollenz and the sea phages program at USF!
@hans-petermuller4771
@hans-petermuller4771 11 месяцев назад
Very interesting. Two questions: 1.Do these phages naturally use the pumps as a entry receptors. 2. Is there a chance that the bacteria mutate such that the pump remains active but no longer works as a phage receptor? Thanks very much in advance.
@bioquimica_animal
@bioquimica_animal 11 месяцев назад
Or what if phages mutate and gain the ability to infect mammalian cells?
@hans-petermuller4771
@hans-petermuller4771 11 месяцев назад
This is extremely unlikely or impossible because the respective host cells differ in many ways.
@DemonZest
@DemonZest 10 месяцев назад
@@bioquimica_animal There is already virus very adapted to infecting human cells ^^ Phage are too specialized into specific species of bacterias.
@MrDeathray99
@MrDeathray99 10 месяцев назад
@@hans-petermuller4771 Just like how bat studies for coronaviruses was 'unlikely or impossible' to spread to humans because it used receptors humans don't have. Or 3 days ago a research lab in Guanzhou has had 3 workers die suddenly due to an infectious cancer which should not be possible as cancers are not infectious.
@chinese_bot
@chinese_bot 10 месяцев назад
Love that this is a sponsored video that pops up with searching “mycoplasma pneumonia” haha. I anticipate that this video is about to become very popular. It’s going to be a rough winter.
@NETWizzJbirk
@NETWizzJbirk Месяц назад
Problem is it will quit working the moment your body is immune system starts attacking the virus that is killing the bacteria
@DarkWarchieff
@DarkWarchieff 24 дня назад
Prednisone
@hxtunq
@hxtunq 11 месяцев назад
Can't wait to see this video!!! T___T
@scicommlab
@scicommlab 11 месяцев назад
We can't wait for you to see it!
@raene52
@raene52 25 дней назад
Use for EEE?
@garydodge2949
@garydodge2949 5 месяцев назад
So much information except the info we need . How in the hell can I get my hands on phages. My girlfriend is dying. At the rate the bacteria is growing in her she doesn't stand a chance if I don't know where to get the phages we need.
@BLACKLABEL405
@BLACKLABEL405 Месяц назад
What happens to her? How is she?
@mdzahidhossan7336
@mdzahidhossan7336 Месяц назад
Sir iam need phage threpy
@mdzahidhossan7336
@mdzahidhossan7336 Месяц назад
Sir my need phage threpy
@rodrigomelendez1545
@rodrigomelendez1545 11 месяцев назад
Please upload more often 😅
@scicommlab
@scicommlab 11 месяцев назад
Two more films are coming in the series! Next one on Electric Microbes will premiere November 2nd. Click "Notify Me" button on this video to get an alert to join us when the time comes: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-cXARtgRHFsM.html
@davidhale6929
@davidhale6929 10 месяцев назад
What are the side effects of using phages in humans?
@sneakerbabeful
@sneakerbabeful 8 месяцев назад
Side effects are eliminating one specific species of bacteria from a persons body.
@Cin9999
@Cin9999 11 месяцев назад
This is MEGA funny to pretend this is innovative when Georgia has been doing this since the 1920ies lol.
@rodrigomelendez1545
@rodrigomelendez1545 11 месяцев назад
What are you talking about?
@davidbahry9092
@davidbahry9092 11 месяцев назад
​@@rodrigomelendez1545 phage therapy was actually invented before antibiotics! It fell out of use in the Western world when antibiotics were discovered, but former USSR countries kept the tradition alive, especially at the Eliava Institute in Tbilisi, Georgia Fun fact: America's first Nobel Prize in Literature was for a 1925 novel about a doctor who independently discovers phage therapy ("Arrowsmith")
@Cin9999
@Cin9999 11 месяцев назад
@@rodrigomelendez1545 Go on Wikipedia
@Downtrodden_cat
@Downtrodden_cat 10 месяцев назад
​​@@rodrigomelendez1545 i understand what he means and a few google search said this phages are being used in Soviet Union countries ie Russia and the Eastern Bloc because the west denies them antibiotics for political reasons so they use viruses these to kill bacteria in the body to cure illness and on the special occasions they are being used there
@bruhmoment879
@bruhmoment879 9 месяцев назад
⁠@@rodrigomelendez1545The Soviet Union and its states used to use phage therapy as a common way to treat illness until mass production antibiotics was available to them,for Georgia,though they also use antibiotics,but phage therapy is still a common method of treatment,you can even find phage paste for open wounds there
@SteveHazel
@SteveHazel 11 месяцев назад
why do ya call em phages instead of viruses?
@davidbahry9092
@davidbahry9092 11 месяцев назад
It's short for "bacteriophage" (or "bacteria-eater"), the kinds of viruses that specifically infect bacteria It is a bit silly because that means we're just calling them "eaters," but oh well-etymology often falls between the cracks of language!
@SteveHazel
@SteveHazel 11 месяцев назад
@@davidbahry9092 i mean every virus eats bacteria by definition. seems like just a fancier word which implies tryna be fancy for no good reason. aw well
@davidbahry9092
@davidbahry9092 11 месяцев назад
@@SteveHazel every virus attacks cells, but not every virus attacks bacteria! E.g. the smallpox virus only attacked human cells; different kinds of influenza viruses attack different mammal and/or bird cells; etc.
@serenitybay5544
@serenitybay5544 9 месяцев назад
Gc-MAF ????
@Brandon-dl2wf
@Brandon-dl2wf 8 месяцев назад
Super bug fighter ginseng from tablets not from roots as you were
@malachiwhite2195
@malachiwhite2195 3 месяца назад
Does this kill the super bug
@Phil-D83
@Phil-D83 3 месяца назад
Attack it from multiple vectors
@jenlf2855
@jenlf2855 6 месяцев назад
💜👍
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