Frances Arnold: New enzymes by evolution 

The way you implement the Noble ideas into society is the prize - How it benefits mankind.

Congratulations for the historical achievement 😍😍😍

congratulations , unbelievable, and it is the only near ever possible hopes in the future

Thank you mam for your valuable lectures, regards from India 💐

It's a new world to run in the speed of light! Thanks for Dr.Frances Armold's efforts!

Madam i want to be your student.

oh wow, what a inspiring and amazing talk about biocatalysis.

Congratulations, I am diehard lover of GENETICS

Awesome talk

Exciting!

Congratulations Frances Arnold

Congratulations

let us give a big salute to our beloved Darwin too for paving the way for wonderful scientists like Francis Arnold....it is high time a global investment is ensured to take up such great researches in evolutionary biology esp in the light of thee Covid19 outbreak...virology should have a strict evolutionary orientation...

Congratulation wonderful invention

Congratulation Madam

intresting

amazing woman

👏👏👏

may i reupload this video to a nonprofit site bilibili? I'll attach the link below

Wow

Is t here currently any research on creating designer proteins/ enzymes. By which I mean using AI AND SUPERCOMPUTERS to create enzymes that don't exist in nature. These could be used for example break down PFAs.

Brilliant research that shows intelligent design.

29:51 she just @vsauce 'd us

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-05r-FLGtsEQ.html: "[The protein space] is bigger the United States national debt." Great sense of humour. Congratulations !

🤗👍👏👏👏👏👏👏👏👏👏👏👏👏👏

Wake up

Brilliant. Try again, fail again, fail better harnessed as a portal into a whole new chemistry of life, I suspect frances Arnold will be back in Stokholm ere to long.

playing with chemistry and calling it evolution..its reaction.

Fascinating! I don't mean to take _anything_ away from this excellent work, but I'm amazed that such brilliant people have so much naive faith in evolution. At 4:28 it's acknowledged that enzymes are *so well designed.* 11:09 _"Imagine just a single protein a few hundred amino acids long, you've got twenty amino acids to work with. That's a really big space of possible sequences. ... It's a really _*_big_*_ number. And, it's mostly empty. ... So how do you search a space of enzymes that's bigger than you can even begin to comprehend and mostly empty?"_ Good question, but an even better question would be, how did _"nature"_ find the original enzymes? Oh sure, we know a mutation or two can wobble around an _existing_ enzyme and change its function slightly, as you've said and demonstrated. But that _"really big"_ space of 20^450 (or 10^585) permutations is, as you said, well beyond astronomically large. A few billion years just won't cut it. A little math, with assumptions very favorable to evolution, will easily show that _"nature"_ couldn't have found _any_ of those enzymes in a trillion trillion trillion trillion years. Seriously. Make some assumptions and do some math.

I compliment your work however as an engineer why are you not looking at the Crux of the problem you're part of the cog of the problem I understand you have a career a life a reality but you do realize you can change that reality in a instant, right? So which reality have you discovered? there's so many out there... for all of you, the natural world doesn't really need anybody's help however continue on as part of the cog of the problem and not the solution but we all understand you're driven by your academic nature to fix things remember to fix something you need to know what the actual problem really is, not a Band-Aid, especially in biochemistry

4:00 "Biology is great, but it can't do what I can do."(?) Let's not forget, biology and chemistry created you, silly. I'm just saying, it's the more impressive thing.

What’s so unreal about her is that she probably would have revolutionised solar power if she stayed in that area. Brilliant. Destined to make a big difference