So as I understand it, frequency probably works like this example. X = hypertrophy from doing 5 sets 1x/week. If doing 10 sets 1x/week, hypertrophy = 1.5X (or at least less than 2x) If doing 5 sets 2x/week (10 sets total per week), hypertrophy = 1.5X (0.75X + 0.75X) so the same. If you train more frequently, you get repeated bout effect, so the hypertrophy evens out (at least with lower than normal volumes) But we dont know how far that stretches, whether 20 sets 1x/week is better than 10 sets 2x/week. We wont know until we have some studies with that specific design.
Honestly , if i do 6 sets of something. I think the body part will fall off. Doing that 4/week makes it easier. But still 6sets for me is about right as max volume i do in a workout
