A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
Thanks very much for this wonderful video! I just met a tenosynovial giant cell tumor without any giant cells, but the presence of foamy cells and the collagenization of the stroma helped me a lot to achieve this diagnosis. Thanks for your teaching video a lot!
My pleasure. A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
Super helpful review, as usual. Especially topical for me given a sclerosed GCT on my desk this week from finger, which threw me a little to start with as very scant on the actual giant cells. But thanks to your rules, am happy!
What a great presentation! I like the clues at the bottom. Thanks for all your teaching. It's helping me as a histopathology trainee in the UK (looking for ladybirds).
Thanks for the amazing concepts, comparisons and the ever lucid way of explaining Sir..Feel all the more in love with this subject after seeing your videos!
Can you also do a video about differentiating ddx for the hyaline deposits! Like EPp vs lipoid proteinosis vs colloid millium vs nodular amyloid. The more I look it up and try to learn it.. the more confused I get! Thanks in advance
Haha you’re not alone! I think they look nearly identical as well and I have to look them up every time I am considering them. Maybe that’s a good reason to make a video though...
Common? My understanding was it is a rare disease... I also had a large nodule (Giant cell tumor) in my knee-It pressed on my ACL and I couldn’t straighten my leg. In addition, I had a lot of diffuse growth. Both types returned less than one year after the resection and synovectomy. Waiting for the new chemotherapy. I certainly hope that they keep on top of it because if someone misdiagnoses it non-malignant in error, this is a very deadly sarcomatous type cancer if it does in fact become malignant!
Thank you! No I haven’t done one on malignant transformation in these because it’s incredibly rare. I’ve only see one or two (back in fellowship) and not sure if I even have recuts of those.
@@JMGardnerMD Thank you so much. A few days ago, we received a case of a malignant transformation of GCT of tendon sheath, in our department. I will do my best to send you some histological slides, in case they might be useful to you to make a video about this rare and infrequent type of tumor.
Thank you for your presentation. My query is about prominent angiomatous proliferation of capillary endothelial cells in addition to plenty of haemosiderin loaded histiocytes.
I don’t understand. Are you asking if these things can be present in tenosynovial giant cell tumors? Abundant hemosiderin is a common feature. But I don’t recall seeing prominent proliferation of capillaries in this tumor before.
No, Far from it! I’m just a pathologist trying to share the small area of pathology that I know about with others so they can better help their patients. But thank you for the kind sentiment. 😊
I did surgery for giant cell tumor of tendonsheath nearly two years back in my right ring finger.biopsy confirmed diffuse gctts and it is benign.Now I had a pain in my joints (tumor site)without any swelling. What can I do for this?.I met a orthopedic surgeon for my previous surgeries.
It is probably a good idea for you to visit your orthopedic surgeon again and have them do a work up to see if they think the pain is related to a recurrence of your tumor or something else. Best wishes for a quick healing.
I was diagnosed with gct of tendon sheath in my right hand thumb . fnac test confirmed gct. And yesterday I went through excision biopsy. My Doctor once again asked for biopsy of removed tumor. Is this going to worrying .I have this tumor since last 5. To 6years painless. But slowly its size grew up.
They are benign tumors but most of the time they are removed surgically. However if yours is not causing you any symptoms and you don’t want another surgery, then you can discuss with your doctor the risks vs benefits of choosing to watch and wait rather than remove the tumor now. If it were my own thumb, I would probably personally choose to have it removed just to avoid having a mass there if nothing else. But as you are not my patient and I am not your doctor I can’t give you official personal medical advice. Discuss with your own doctor so you can make the best decision for you. Best wishes.
@@JMGardnerMD thanks Sir but please tell me one more thing is fnac test is accurate and I already had removed gct on my thumb . now what is reoccurring rate
I wad diagnosed with Giant cell tumor of the tendon sheet on my 5 finger of my left hand. Now I am showing the same symptoms on the 4 finger of the left hand. Is it posible to get it on multiple areas? What should I do? I have visited 3 different surgeons and the don’t know what to do.
I can’t recall seeing a patient with this in 2 different places but I think it is possible. Did your surgeons do an MRI of the left hand to see if there is a mass present? Did they do a biopsy or surgery on the left hand? A hand surgeon or an orthopedic oncologist (a specialized Orthopedic surgeon that deals not only with malignant but also benign tumors of bone and soft tissue)...they are familiar with this type of tumor. Most other doctors would not be very familiar with it. Please be sure to talk with your surgeon, ask them to explain what they think is going on and what the options are for dealing with the issue. Best wishes for good health.
Jerad Gardner, MD thanks for your response I am from Puerto Rico here we only have 2 specialists in hands and they decided not to take my case. Yes they did an MRI and it shows soft tissue. It keeps growing and it gets so painful, they only inject me for the inflammation and that’s it. I don’t know what else I can do. Really appreciate your suggestions
I cannot recall ever seeing a siderophage that looks like these in a DF. But regardless, the other features discussed here would easily differentiate tenosynovial giant cell tumor from DF. And these tumors rarely involve the dermis which is where most DFs are located.
That just looks terribly pathological and one might even auspect Rheumatoid Arthritis among all the neoplasia. It is highly plausible that an idiopathic autoimmune disease is conducive to many other disorder, neoplasia amongst many others.
