Genetic Engineering and Diseases - Gene Drive & Malaria

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We have the choice to attack one of our oldest enemies with genetic engineering. But should we do it?
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Lucien Delbert, Mike C, Ricardo Chavarria, Juha Wellman, Zachary Jordan, Patrick Chang, Adrian Mihali, Nicodemos Nicodemou, Lacey Larson, Austin Earnest, Andre Wee, Koroslak, Alex Brady, Roberto Cano, Andreas Stokholm, Plamen Ivanov, E Smith, Kieran Hunter-East, Christopher Trinh, Tony Kwok, Adam Rabenstein, Andrew Whitehurst, Alena Vlachova, Mackenzie Broadbent, Andreas Hertle, Martin Petersen, Kasturi Raghavan, Gregory Griffin, KiaTheDead, Aaron Stevens, Jimmy C, Benedikt Jaletzke, Jonathan Bowler, Zdravko Šašek, Wouter Stokhof, Zealotus, Long Vu, Fatman13, Jeremy Dumet, Miles Spoor, Mirton I, Al Fl, Jonathan Carter, Stanislaw Wasowicz, Marek Turcani, Francisco Santos, Justin Choi, Dagoberto Chapa, Chip Salzenberg, TinFung, Bob Bergeron, Peer, Justin Elstrott, Rachid Malik, Octavio Astillo, Romain Isnel, Rich Sekmistrz, Kuosora, Mozart Petter, Justin Jeffries, Nicola Licheri, Bahram Malaekeh, Florent Petterschmitt, David Mark, Gaby Germanos, Shweta Bharadwai, Lux Stamm, Marc Johann, Joe, Nefaur Khandker, Anders Madsen, Sarah Yoshi, monoxide, Brandon Meador, Dovydas Bartkevicius, Tyler Vigen, Michael Niella, Gordon Timilty, Slava Dzyba, Bagel Krippen Chandra, KodinCage, Miikka Harjuntausta, Magid Elgady, Vince Houmes, Irae Carvalho, Josh Talbot, Mr.Z, Pawel Urbanek, Russ Clarke, Lucas Tostes, Oscar Chamaria, Zachary Langdon, Steve Bollenbaugh, Xiaogiang Zheng, Peter LoPinto, Jenny Nordenborg, Evan Faas, Greg Fowler, Cicmil Mladen, Canut Durgun, Malovich, Cedric, Dave Anderson, Jones, Elliot, Denis Dube, David Allen, Dawson Reid, Jake Zwirdowski, Denis Leu
SOURCES AND FURTHER READING
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Harvard FAQs on gene drive:
bit.ly/1TYNIAo
Research paper on using CRISPR for malaria gene drive:
bit.ly/2cGXNqp
Nature article on engineered mosquitos:
go.nature.com/1Ij39yS
STAT new article on using gene drive against Zika:
bit.ly/2ctw24X
Tech review article on using gene drive against malaria:
bit.ly/1V0Qpr7
Smithsonian on deadliness of mosquitos:
bit.ly/1sqQ1D7
Science article about the risks of the technology:
bit.ly/2dgtpCt
New Yorker on Pros and Cons:
bit.ly/1PTKGlt
Gates note on death rate through mosquitos:
bit.ly/1UdvIqI
Status quo on field trial in the U.S.:
bit.ly/2b16ufu
Evolution working against gene drive technology:
theatln.tc/2cmMjau
Research paper on evolution of resistance against gene drive:
bit.ly/2cGWPKO
Science news on possible safety feature for gene drive:
bit.ly/29I0Z26
Help us caption & translate this video!
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Опубликовано:

20 сен 2016

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Комментарии : 19 тыс.

@kurzgesagt 5 лет назад

You want to learn more about science? Check out our sciency products on the kurzgesagt shop - all designed with love and produced with care. Getting something from the kurzgesagt shop is the best way to support us and to keep our videos free for everyone. ►► kgs.link/science (Worldwide Shipping Available)

@dldez8590 5 лет назад

Can you please fix your atom in the intro?! Its supposed to have two electrons on its first orbital not four

@xwater1361 5 лет назад

👍

@turkuas23626 5 лет назад

@@dldez8590 thanks Einstein

@Nugcon 5 лет назад

only 42 likes wow

@rejjaq7627 4 года назад

What if plasmodium develops resistance against the antibodies?

@YMS 7 лет назад

I'm okay with eradicating mosquitoes.

@Stalast. 7 лет назад

Sup

@dylanbreheny4359 7 лет назад

Don't mind me, just another commenter with no Subscribers passing through--- Wait, what are YOU doing here?! At the bottom of the comment section, no less!

@mahatmaghabdu7592 7 лет назад

i should have assumed a educated man like you watches kurzegesagt

@Petrico94 7 лет назад

It'll be next to impossible and besides not all mosquitoes even suck blood. Plus other animals eat them so we'd need to get more flies to replace them or everything is fucked

@DeineLieblingsvideos 7 лет назад

Seeing this comment excited me more than the fact that Brad Pitt and Angelina Jolie broke up.

@Derpsider 7 лет назад

so the mosquito is one of Our Deadliest Enemies? well then, I just killed one of them on the wall and will call myself from now on a *WAR HERO*

@ImperiaGin 7 лет назад

If you get malaria would you have ptsd also ?

@nonenothingnull 7 лет назад

I wonder if we could differ the genetic modified from regular

@bassiroucamara5711 7 лет назад

Thank you for your service!

@PacoCotero1221 7 лет назад

TRIGGERED

@stefanilserbo2 7 лет назад

In the second world war, they didnt call you a hero if you killed one nazi because there were millions of them... when your kill counter goes over 1 billion, then we'll call you a hero ;)

@swiftycortex Год назад

"Imagine that, killing someone from their inside, and then using their skin as camouflage. Brutal!" Imagine that, sharing scientific information with love, and highlighting the horrific. Contagious! Thank you Kurgesagt, every video I have watched has been a concise, informative, and joyous piece of art, which I have loved watching equally as much as it's made with love.

@arvt_ 2 месяца назад

they stole my tatics bro

@NguyenMinh792 Месяц назад

a wolf in a sheep’s clothing

@lunawazhere Год назад

It's now 2023, and I am very pleased to inform this video that genetic mosquito engineering has been a success in many countries, and I have visited one called "Singapore". This country uses Project Wolbachia, a name they came up with for a project, in which they released thousands of genetically modified male mosquitoes into the surroundings to mate with female mosquitoes and produce harmless offspring. Some versions of the modified mosquitoes completely block off the birth of female mosquitoes by killing them even before they turn into adults. As a result, more male mosquitoes are hatching than female mosquitoes and dengue cases in Singapore are going down rapidly. I am proud of this country and every country in the world that has tried this genetic mosquito project. This might just be what we all need to overcome malaria, dengue, zika and many other diseases mosquitoes have brought horror upon in this world.

@stressed_vivi 7 месяцев назад

You've given me a cause to believe in humanity thank you.

@onlyms4693 7 месяцев назад

Sheeshh... W Singapore, let's hope Malaysia and Indonesia do the same

@doggommm6963 3 месяца назад

@@onlyms4693Malaysia actually did this too, though not the whole Malaysia, mostly KL

@mo5h3rman 7 лет назад

Just build a wall and make the mosquitoes pay for it.

@greaterspirit4033 7 лет назад

the rate of sarcasm is too high..😂

@LordyNateur 7 лет назад

Mosquitoes don't have jobs. How are they supposed to pay for a wall?

@TheRisingDzn 7 лет назад

its sarcasm u know?

@Eddy-nn7wj 7 лет назад

They have jobs! We work to get money --> to make a living, buy food, home.. They work to get the living literally, by gaining life essence as their custom.

@user-vp6cn4kb2t 7 лет назад

They evolve to steal wallets!!!

@70jcarbon 7 лет назад

Malaria too OP for game, must be nerfed/banned. - Immune System

@erikjohnson315 7 лет назад

But the admin(human) are too busy

@DavidAllen-px7gr 7 лет назад

Fortunately, one of the players has found the console. (Dropping the joke, at least humans found C.R.I.S.P.R. & CAS9) [Edit removed ambiguity]

@zaoralj 6 лет назад

70jcarbon thats called overwatch nerfing XD

@catrinasmith5366 6 лет назад

David Allen said he is only provide any service or the trash container itself it was her first day on the phone fighting with Westgate shopping mall and the best part he wearing it like Now Wal-Mart shut down for the other families such a tragedy for me the pic of the other illusion that was given but most illusion of course you have to show it to the next level and I know it but you continue loving it up tonight or tomorrow night with the correct names and stuff like the orange 58 chairs for you have become 8th and chairs sometime.

@katraena5225 6 лет назад

God: -Buffed Immune System

@natileroxs5226 Год назад

As someone with beta thalassemia, I'm not too worried about contracting malaria. but the rest of the symptoms aren't exactly a great trade-off even with a mild version

@smiley5836 Год назад

what that

@AlOqab_ Год назад

@@smiley5836 cuz thalassemia/ sickle cell anemia gives u somehow an Immunity to malaria

@di_bortz Год назад

@@AlOqab_ bc of the shape of the blood cells the malaria cant hide itself

@bananaraptor7747 2 года назад

5:15 Damn, those fleas are *menacing*

@grande1899 7 лет назад

So I guess my hatred for mosquitoes is justified.

@ServrHax 7 лет назад

Weird finding you here xD

@yanjia1777 7 лет назад

hi grande!

@angeloanan 7 лет назад

Why are you here lol.

@mattstorm360 7 лет назад

it's not there fault.

@occult14 7 лет назад

yup same here

@magicman8166 7 лет назад

I love this channel, i wish school was like this...

@magicman8166 7 лет назад

Really good visuals and brief but acknowledging facts!

@aphoticlight 7 лет назад

Yep

@Kollynator 7 лет назад

Tell me how they change the DNA then....

@pvic6959 7 лет назад

mainly i _LOVE_ the visuals. they can even make a boring lecture fun

@astodone9022 7 лет назад

If school was like this I'm pretty sure everyone would become an Einstein but the government doesn't give a shit.

@nooneofconsequence5847 3 года назад

These videos help to remind that the professionals and experts do really consider all the possibilities along with consequences in science.

@Lowkeykindabi 2 года назад

Bro!!! I am living in Africa and lets say I get malaria like every two months since when I was six I would get really sick😪.......now I am 12 and my immune systems are stronger to malaria and still living!!!! Thanks immune systems😊

@Lowkeykindabi 2 года назад

Don't forget vaccines

@sahilbaxi 3 года назад

Coming here after the news of genetically modified mosquitoes being released in Florida, and it suddenly makes more sense

@muratakpinar9094 3 года назад

For real? Great news

@ayasya. 3 года назад

what happened sorry ive been hiding in cave im confused

@kornelfarkas6224 3 года назад

@@ayasya. same, never heard about it , but i'm happy about it

@yoavboaz1078 3 года назад

wait really?

@Lumberjack_king 3 года назад

What I haven't heard about this. I hope this is a good thing and it doesn't back fire final last words sorry I had to

@yes4612 4 года назад

Kurzgesagt: about 5 kids have died since this video started Murderer: *watches video multiple times*

@user-zg4dx2sw3y 4 года назад

Makes sense to me 👍

@Monarch_Prime 4 года назад

Makes sense

@xxmarblesodaxx9798 4 года назад

-_________-

@aidanhays8348 4 года назад

100% plausible

@goldensupmanz 4 года назад

[sad dead meme noises]

@oslopaper5538 2 года назад

Our recent lesson in biology was genetic engineering and the timing of this video popping out couldn't be more perfect. Great video as always!

@nithen8179 2 года назад

Can we just appreciate how their animation has improved over the years

@brendanb4361 7 лет назад

We should use CRISPR to save the bees so we don't all fucking die

@ricksanchez8081 7 лет назад

how do you think we should do that?

@jeremiaholszewski1844 7 лет назад

Same reason of how we are eradicating mosquitos well eradicating the diseases Mosquitos spread. But I don't know if when someone is given CRISPR it's genetic. That's my only question

@ricksanchez8081 7 лет назад

not why,what could we alter to help the bees?

@Deathmachine513 7 лет назад

Make the bees more resistant to pesticides that are currently killing them?

@ricksanchez8081 7 лет назад

i don't think you can just flip a switch in their DNA or add something like that the only i see them building a resistance to that stuff is by evolving by themselves but im not a scientist im a student that's training to be a doctor behind a screen with a keyboard and im not too caught up on the subject of DNA

@R9000 7 лет назад

If this sort of thing becomes common, are we going to get video game-like patches for planet earth? "X species is becoming endangered because it doesn't readily produce enough offspring." "Oh don't worry, that'll be fixed in patch 2.6.7 beta. I heard they're nerfing mosquitoes too, people have been complaining their 'disease attack' was a bit too OP."

@BamseTheBear 7 лет назад

you are terrible

@SUPERSamuraiGaming 7 лет назад

come the fuck on

@R9000 7 лет назад

What's up man?

@SUPERSamuraiGaming 7 лет назад

ceiling man.

@metcas 7 лет назад

Would make sense if we're destined for Type-1 civilization.

@Kam5 2 года назад

Just leaving a comment here to say that I'm re-watching your videos all these years later because we're doing topics that you've covered in my senior biology class and without your videos I would be failing this class. tysm!

@aryanasmith4426 Год назад

I extremely like the video, man. Very helpful and informative. Thank you very much. It is presented so well too. Great, positive work.

@-hitman-9103 4 года назад

The immune system really needs a buff in the next update

@adorablecheetah2930 4 года назад

You are from that animal channel right

@KalleVonEi 4 года назад

Tierzoo knows how this engine works

@badgerous8320 4 года назад

the update is under development the video just said that

@anunayy 4 года назад

The game is supposed to be challenging tho, else there will be no fun, and in any case the "Modern Medicine" exploit is too OP anyway.

@neonicplays 4 года назад

Anunay ikr humans are becoming too end game

@user-by7gk4nn7v 7 лет назад

How can people dislike a Kurzgesagt video?? how can you find fault in their videos? who are these people?!?! mosquitos?

@hawkecrail5186 7 лет назад

Although I don't, I see why. TheY have different opinions than the kurzgesagt team

@MegaMGstudios 7 лет назад

people who hate genetic modification

@awesomeman3750 7 лет назад

Parents/Religious people who believe that vaccines cause autism.

@arjunmodi1729 7 лет назад

People who held their phones upside down

@1footflash 7 лет назад

mosquitoes hated this vid.

@ElTwOJaY 2 года назад

As an employee of the Umbrella corporation I can say that genetic engineering of viruses is the future 😀

@passerby4507 2 года назад

6:10 That's not how heads are supposed to turn.

@peterhuwe8709 2 года назад

lol

@TheKrensada 2 года назад

Speak for yourself.

@leinadlink 7 лет назад

I think it should be tested first in an enclosed enviroment to see how the mosquitoes develop and evaluate it's effectiveness. We want to help those affected by that terrible virus, but we don't want to make a mistake that could create a bigger problem.

@rockets-dont-makegood-toas7728 7 лет назад

true true

@djr5995 7 лет назад

Good point. By doing so they could get a clearer idea about how fast the trait gets passed on and how long it will take to change the whole population

@bigbluebuttonman1137 7 лет назад

Yes, I had the same exact idea in mind.

@rancidmarshmallow4468 7 лет назад

the problem is that an "enclosed environment" large enough to properly model it would be huge, costly, take years, and possibly not be accurate because of the lack of other factors like actual humans to bite (and use to spread the disease) among other things. (you can't put humans in there because they would die. putting this here because inevitably somebody will say "well then just put those other factors in")

@sasuke2910 7 лет назад

I've sure that's been done countless times by now. What we don't know is how this stuff works when it's released into the open environment.

@James33498 7 лет назад

Everytime I watch Kurzgesagt's video, it feels as if I'm watching a movie.

@joshuapeters567 7 лет назад

I feel that way too

@ScibbieGames 7 лет назад

James Lupei the production is high quality indeed

@jeanicehoffing8935 7 лет назад

Every time I watch a Kurzgesagt video, I feel like I have to rethink a lot of my views and ethics

@jum8082 4 года назад

@Paddy Lawn that is like the opposite of school

@masupalami33 2 года назад

I contracted malaria in utero (thanks mum), it was obviously untreatable at the time. The doctors in Papua New Guinea treated mum with tetracycline which gave me grey teeth. Throughout my life I’ve suffered relapsing malaria symptoms and liver problems. Luckily, as an Australian, I’ve access to excellent free public health care. There are so many who don’t. I wouldn’t wish this disease on anyone.

@Krunchier Год назад

5:52 "oh god a muto?" MAN THAT GODZILLA REFFERECE JUST HIT. PERFECT

@fish6550 4 года назад

“Imagine that! Killing someone from the inside and using their skin for camouflage!” *Laughs in leather jacket*

@haztetv7226 4 года назад

@Mohammad Al Arab You can do it for military purpous, like colour it for camo in military. So yea you're just a sand dumbass

@paryudisaditya8845 4 года назад

@robizzlor i wish you know

@frog8878 3 года назад

@robizzlor dumbass

@Vissorilio 3 года назад

Well at least you dont use it as camflouge, also you can say the same thing for fur coats except some don't kill the animal and only try to get the fur of the animal.

@BB-uo1qy 3 года назад

Are you calling yourself a cow?

@Qureas 7 лет назад

I want a DNA sword in a RPG!

@squartron2473 7 лет назад

why not Terraria? It would fit perfectly

@hennyzoel7062 7 лет назад

Jørn Haugum well screw it i want it in real life of curse

@shaisai6798 7 лет назад

You'd know what would be cool if that happens? What if it has a chance to change (insert enemy monster here) in some way? ex. giving it the ability to inflict you with some sort of fire-damage, or another ex: making its attack lower

@shivaprakash4717 7 лет назад

lol

@brandonvelde5774 7 лет назад

The sword will work like this, whenever you hit an enemy you would gain +5 points of health back. And if you'd got 5 kills with it you would be able to heal you and your friends to full hp.

@claricesiau7905 3 года назад

i love this youtubes channel videos as i like science,things about space,learning about diseases and nukes

@fastlion2747 2 года назад

That’s what I said when a video from this channel called The Most Efficient Way To Destroy The Universe came up on my recommended

@Plantsandanimals979 Год назад

In 2021 there was 617,000 deaths from malaria which is 1717.8 deaths a day or 71.5 deaths an hour which also equals over 1 death a minute and this possibly could have been prevented

@puggumpus 3 года назад

Living in Africa, as a young kid, I've heard of malaria once, and every single time I've gotten a mosquito bite, I was getting ready for death...luckily those preparations were never used

@Jensenrobinb 3 года назад

Phew

@puggumpus 3 года назад

@@Jensenrobinb ikr

@bluejacket4429 3 года назад

Funny enough, I lived in Africa when I was a kid due to my parents being missionaries. I got Malaria once, and that was probably the most miserable week of my life as I felt terrible just standing up, and vomiting was frequent. Though as you can see, I'm not dead, so I suppose that's good. Though a missionary lady that I knew passed away because of Malaria. Personally I wouldn't use the Gene modification for mosquitos though.

@fernandorobinson8272 3 года назад

@@bluejacket4429 why not? You don't want others to avoid the terrible experience you had?

@bluejacket4429 3 года назад

@@fernandorobinson8272 It's terrible, yes. But it's avoidable and survivable. It's hard to do either of those in a 3rd world country, but it isn't the only solution. Gene modification is the easy way out, and one of the biggest impacts it'll have is on the food chain. A lot of animals need mosquitoes for food, and I don't know how well they'd do without them.

@sebastianpoppenborg6850 7 лет назад

I always get goosebumps when you say 5 People died of Malaria since the video started.

@geilerhengst6892 7 лет назад

pussy

@pilzening2810 7 лет назад

Goosebumps of happyness?

@geilerhengst6892 7 лет назад

Mitglied der Pilzarmee oh yeah maybe

@antonioetv 7 лет назад

Its sexually arousing

@moddy252 7 лет назад

@lastrusomg 2 года назад

5:41 not mr DNA

@neveyjcammans808 Год назад

This was really interesting, and super helpful for my biology assignment! I would really like to hear your opinions on the de-extinction of animals (woolly mammoths, tasmanian tigers, etc.) using CRISPR technology, since it sits similarly. Thank you!

@aidanrozema8522 5 лет назад

I did my health fair project on malaria, inspired by this. I got an A+ so thank you.

@PsychonautTV 5 лет назад

Congratulations! Nice work!

@erek 5 лет назад

Congratulations!

@PhoebeJaneway 5 лет назад

Good job! Bet your teachers didn't know that this is already researched! I didn't have a clue and I'm a biology teacher. But I'm definitely going to teach my kids about that. Sooooo interesting!

@erek 5 лет назад

@@PhoebeJaneway Yes, you should definitely teach students these things. I hate teachers because they are just teaching boring things. I learn more from youtube than books/teachers.

@PhoebeJaneway 5 лет назад

@@erek But on the other hand: some things are boring and STILL have to be learned like maths, history and politics, a foreign language and some basics in chemistry. Life isn't (oh what's the English term) a "Wunschkonzert" .....ah, there's no English idiom like that....So: Life in our modern world isn't always about what you want. And that's a lesson teachers should teach their students and thus make them strong for this world, don't you think?

@marclikesmoths 5 лет назад

That CRISPR sword was highkey aesthetic

@namelessguy199 5 лет назад

Need a skin of that in csgo

@WAZZA1235 5 лет назад

I guess gene editing is a....double edged sw- ok i'm out.

@silvertheelf 5 лет назад

AlliedExplore, kill all misquotes, effect all organisms, all organisms die because no misquotes, barley any organisms die because of misquotes, they are so popular they are a prime food source for many organisms, but it’s malaria we need to wipe out.

@AlanTheNoob 5 лет назад

How do i give all my money to the investigations so they will kill Malaria ;-; I'm sure that they van kill it but they don't have money :(

@notaweeb4177 5 лет назад

Did you say, *A E S T H E T I C*

@user-ej4ox8vg1u 3 месяца назад

These videos always make me feel smart 😊

@Coreykoon Год назад

I literally have malaria as I’m watching this. Release. The. Mosquitoes.

@CdeCiencia 7 лет назад

Since the biggest problem with modified mosquitoes could be the parasite adapting to become stronger, couldn't we test its interaction in the lab on a reduced scale and then proceed if there was no adaptation?

@imveryangryitsnotbutter 7 лет назад

Sure, but we'd have to make abso-fucking-lutely certain that the test population is completely sealed in.

@DrawCuriosity 7 лет назад

One of my friends is starting cutting edge research on Wolbachia very soon, hopefully in December we will have a video on this :) they have done tests with very positive results

@architrungta120 7 лет назад

*reduced scale*. That's the problem.

@danilooliveira6580 7 лет назад

they know the parasite can adapt. the problem is how fast the imune population will spread and how fast the parasite will adapt. its like a roulette, you can make a estimation, but there is no way to be sure. maybe the numbers will say that the estimate time of the imune population become dominant is higher than the probability of the parasite mutate, but then the improbable happen and one single parasite end up adapting just before the old population is eradicated and suddenly all effort is in vain

@DrawCuriosity 7 лет назад

I commented before watching to the end, I automatically assumed this was about Wolbachia which is going to be a groundbreaking bacteria which lives in many insects and can be engineered to stop the spread of zika and malaria :)

@stukz7094 7 лет назад

apparantly 455 Malaria supporters found this offensive

@psammiad 7 лет назад

I imagine they're probably anti-GM rather than pro malaria.

@Dailylilyful 7 лет назад

It's just a joke bro

@jbar3762 7 лет назад

Probably, as we all know GMO's are unnatural and therefore bad.... malaria is natural and by the exact same logic must therefore be good................. like arsenic, uranium, and anthrax; all natural stuff is good.

@lewiswright861 7 лет назад

I know, also nuclear weapons using naturally occurring elements, and our friend radiation

@seriouslywittygaming6471 7 лет назад

Thats not the case Anti-GMO supporters dislike the process, because GMO is reletivily new, so we don't know the effects of a long term "GMO-heavy society." I personally think there is far more to gain with GMO than without it, especially with food. There is no way we can feed a population of over 7 billion people with natural methods of cultivating food, GMO makes plants far more resistant to weather and that lets them grow in more environments and seasons. But we don't know how this effects the ecosystem in the long run. Both sides have good points, its not like one side is blatantly retarded.

@thvariableyt 2 года назад

First Ever Animation Channel I Have Seen That Upload Their Vids In 60 FPS :)

@frustik6330 2 года назад

I think we should do this, but why? I've had malaria and I know what's going on and I don't want anyone else to feel it. I'm lucky I'm not dead (I was in a coma)

@ahmadbintahir1562 7 лет назад

3 people died while watching this video... I hope none dies when I watch this the next time.

@Whydoineedahandlepissoff 7 лет назад

I hope more do

@ahmadbintahir1562 7 лет назад

-.-

@memedruglord472 7 лет назад

I hope both of you do next time you watch a video from malaria

@Deathmachine513 7 лет назад

I hope I do.

@ahmadbintahir1562 7 лет назад

Hhhh. Negativity.

@lenvos 7 лет назад

Just do it!

@dailydose8172 7 лет назад

baguette

@cheekysteak5238 7 лет назад

Moldy baguette

@Name-ul8es 7 лет назад

'let your dream come true.'

@papervalley_9918 7 лет назад

what if we did it wrong and made something far worse??

@ivopopov6661 7 лет назад

yesterday you said tomorrow

@user-vy1nu8cn6r 2 года назад

YOU GUYS ARE AWESOME With every single word you choose!!!!

@jasontong217 3 года назад

i love this channel its awesome!!

@PsychonautTV 5 лет назад

Me: *smiles in class* Teacher: what's so funny? Me: nothing. Brain: *_ELON MUSKEETO_*

@eve_avery 5 лет назад

They're electric. The wings are solar panels.

@tempest031 5 лет назад

🤣

@rubellite4480 4 года назад

wow

@akasakasvault7597 4 года назад

Omg

@tohrubo 4 года назад

Does this mean elon musk's dream come true?

@xannax2050 7 лет назад

This video ACTUALLY made me smarter. Actually, this whole CHANNEL makes me smarter.

@drxgium2340 7 лет назад

watch crash course.

@dcs3395 7 лет назад

You should have known all of this

@xannax2050 7 лет назад

yeah, I just started today!

@dcs3395 7 лет назад

Fuckin' know right

@patrickgrey7894 7 лет назад

I agree, me too

@andrewe2875 7 месяцев назад

Old video but still relevant, thankyou! Is the sword in the animation a reference to Excalibur? If so, I find it very appropriate.

@hxl29 2 года назад

My grandmother died of malaria I'm glad it's being talked about more

@williamsledge3151 5 лет назад

Now that I think of it, using CRISPR to change the genes of a creature is the biological equivalent of making a mod for a game.

@alessandroceloria4573 5 лет назад

Mosquito v2.13.45 + Added 3 different sizes + Mosquito can now be coloured + 30% more annoying - Removed malaria

@squishy_boi2524 5 лет назад

@TakingThisWay 5 лет назад

And it can always come with unwanted glitches.

@williamsledge3151 5 лет назад

@@TakingThisWay very true

@cadunkus 5 лет назад

And you can never uninstall the mod.

@triciaf61 7 лет назад

can we get a video on why your voice is so amazing?

@natanaelkristian1342 7 лет назад

Daniel A Freeman I just came here like 5 minute ago and already have orgasm.

@rohanagrawal6132 7 лет назад

ikr

@rickmcbigbolt808 7 лет назад

IKR he kinda sounds like Morgan Freeman

@nathanfrench1551 7 лет назад

Daniel A Freeman yay

@ebolapie 7 лет назад

+Rick McBigbolt I don't think he sounds like Morgan Freeman, but he does sound amazing in his own way. For one, MF has an American accent :D

@likemysnopp 2 года назад

Thank you for the decent explaination

@rudiewatzig2904 2 года назад

5:52 i love that Godzilla reference when that guy says OH GOD ITS A MUTO!

@blumer9615 7 лет назад

Honestly, if my teachers showed kurzgesagt in class I'd be way more excited to go to school.

@KyleAnderson-gh9rp 7 лет назад

Then ask them to

@UnframedAnimation 7 лет назад

tbh

@zacharymagnuson2147 7 лет назад

Frixon same

@Jarnt8 7 лет назад

Mine did, it makes no difference...

@intelbentium1204 7 лет назад

mine showed the measles video.

@ebinmemes2298 7 лет назад

i think screw it, we set off the first nuke expecting it to crack the crust of the earth, as long as this stuff is used carefully it can be the greatest tool ever invented.

@duskyracer8800 7 лет назад

just because one thing didnt kill us all doesnt mean something else we dont understand wont

@Potentialiser 7 лет назад

that's why Mitchell noted "as long as this stuff is used carefully"

@ebinmemes2298 7 лет назад

i think if we don't try we'll never know. we don't stop using hammers because they can be used to bash someone's head in, and we don't stop using scissors because you can stab someone with them. with great reward comes great risk, of course, and no corners should be cut, but this could be to genetic engineering as the combustion engine was to transportation

@theporcupine9993 7 лет назад

+Mitchell Anthony the question is not wether we should try it or not. the question is when shoukd we use it and is it ready to use, is more research needed ? the fact that we already set off a nuke is a bad argument and false reasoning. its nog because bad things happened we should continue doing things recklessly.

@miklosgergelymorandini2340 7 лет назад

Your parallel examples fall short in the nature that using a hammer or a nuke is a one time event. Whereas if we introduce this new genome to the genepool it will be self-replicating, and expanding. And we cannot know for sure WHAT will happen exactly.

@kevineleven5610 3 года назад

For such a gruesome clip it was awesome👹

@danilsmith7292 2 года назад

At the beginning, that DNA sword looks insanely cool

@rorocash7129 6 лет назад

I think people tend to forget that Kurzgesagt makes a simplified explanation of the issue. Which is awesome but also it means that before we completely agree or disagree, we should be educating ourselves more. Kurzgesagt is awesome because it makes you interested in the topic but it's just a beginner's conversation. You should research more into it and think critically about the situation, pros and cons of both sides before joining an agenda.

@ienigmaz8495 6 лет назад

agreed

@Banoffeenyx 5 лет назад

Yah

@jackozbloke5079 7 лет назад

Only the scientists that understand this can truly debate the topic as they know 1000 time more than the average person on this subject and all possibilities.

@Jan-vw5cg 7 лет назад

Where's the fun in that tho?

@davidknight3920 7 лет назад

EXACTLY! I've read up about CRISPR, but my input should never have any real weight on the debate to use or not use it. Only qualified (let me repeat that, QUALIFIED) scientists should decide. I say that because there's a lot of bad science going on out there (check John Oliver's report on scientific research).

@Squidward558 7 лет назад

I have to disagree. Scientists used to universally agree on some very stupid and harmful things, and many still do. I think that anyone should be able to debate these topics as long as they bring valid criticism to the table. This technology is going to effect everybody on the planet at some point or another.

@seriouslywittygaming6471 7 лет назад

agreed with Yewtub, Scientists will think like scientists, if they are going to fuck up the world, let everyone get involved in a debate, because earth belongs to us all and whatever results occur, it will effect everyone

@crimsoncount8215 7 лет назад

I feel like it will go the same way as antibiotics if we use it where we are met with a threat of a constantly changing threat so we try to stop but it just keeps changing to survive the changes

@viniciusfernandes2303 2 года назад

Thanks for the video!

@Evie.Luvs_you Год назад

hii ive been watching ur vids for a long time and youve made me really fasinated in lots of stuff and inspired me to become a doctor but i was wondering can u maybe make a video explaing polio? or the iron lung? pleaseeeee

@EMPBossHacks 7 лет назад

this needs to be a TV show

@thorr18BEM 7 лет назад

It is a TV show.

@squid_cake 7 лет назад

EMP Boss Really? What channel?

@jacksonheaberlin6051 7 лет назад

EMP Boss I agree

@stargirlgamer1315 7 лет назад

EMP Boss this helps me learn while TV is just a distraction to me.

@zepwafels 7 лет назад

Who watches TV now that we have internet?

@bertbuschbertbusch 3 года назад

Hey Kurzgesagt, almost 5 years passed, could you do an update video on this please? Dankeschön :)

@yukinaproductions5647 2 года назад

Fun fact: Biontech, the company which invented the covid vaccine Cominarty in cooperation with Pfizer, announced that they will try to develope a Malaria Vaccine with the help of MRNA Technology.

@blazingfish8486 2 года назад

I think they are being released in some places

@amberblyledge7859 2 года назад

I did not know that was how that was spelled. German is so confusing sometimes.

@almostcertainlynotapotato6528 2 года назад

Dankeschön: Thank you very much, Thank you. Translated from German

@cejuonline 2 года назад

@@yukinaproductions5647 the zombie apocalypse is upon us my friend

@blue_ice4 Месяц назад

trust me, if you ever got a fever, your body did a great job on noticing it

@Connorly800 2 года назад

totally will support on patreon just to have a birb

@marykapodistria7204 4 года назад

As someone who almost died from malaria and just caught it at the comma stage , I think we should use these genetic engineered mosquitoes

@e-deternaldatabase4721 4 года назад

Congratulations you are safe from coronavirus now

@Drealmers 4 года назад

They fear if the gene go wrong and it can't not be reverse back again

@busicals9015 4 года назад

it the gene goes wrong, let us sing a song. we will dieeee from zombies. and then everything WILL be screwed up.

@nattybird1146 4 года назад

F, and its been so long since this video was made, its most likely been tested for bad side affects, they should use it, if karen doesnt make a facebook blog so bad that it stops it, FUCK KARENS, and i havent had any bad disease or virus before, but i know its really bad because even common diseases are horrid, so i hope you have recovered well

@ahall9839 3 года назад

As someone who has died from malaria, I second this

@Nico-nt4id 7 лет назад

Only those who can understand gene editing like scientists and other intellectual people should have a say, for if we're going to trust this into the hands of politicians, they'll probably make the wrong decision

@Tachizuu 6 лет назад

Nicolo John B. David well said!

@vassalofthenight9945 6 лет назад

Nicolo John B. David indeed. Politicians do things that give them recognition and popularity, not things that are wise and right. The decision should be made by non-sided commission of the best scientists who know the topic, messing with nature is risky.

@karinwestscott7822 6 лет назад

Nicolo John B. David No shit sherlock

@peacefulinvasion 6 лет назад

Agreed. What the fuck does trump know about genetic modification?

@htoodoh5770 6 лет назад

Terezi Pyrope Agreed.

@8curious 3 года назад

these videos are so awesome ^-^

@lukask3714 2 года назад

The problem of using this in large scale, scales we can not yet realistically and holistically simulate in a lab, is that an already complex technology meets an basically unknown, vastly intricate, complex system. So the long term and butterfly effects can be of unknown scale and adversity - scales that can horrendously outdo half a million death.

@HelloTher1313 4 года назад

In Spanish, the suffix -ito means small, so a genetically modified mosquito that grew to a gigantic size would be called... EL MOSCO

@arcangelonmagus4239 4 года назад

Emmm. Noup. Mexican here. El mosco exist. Is a regular fly. You mean "El Moscote"

@arcangelonmagus4239 4 года назад

"ito" "o" "ote"

@HelloTher1313 4 года назад

@@arcangelonmagus4239 oh OK, well then, I guess my Spanish is getting a little rusty lol

@nomellameshomerollamamehomer 4 года назад

@@HelloTher1313 don't worry, he said mexican spanish, than it's so different from Spanish, "mosco" it's a good joke for a person from Spain, because we don't have that word, there's one so similar "mosca" in English "fly(insect)"

@HelloTher1313 4 года назад

@@nomellameshomerollamamehomer oh, I guess my Spanish isn't that bad then 😀 thanks for telling me, I forgot how much the different versions of Spanish vary lol, I learned the version most common in Spain

@violetazake8323 7 лет назад

Who on earth dislikes a free, entertaining and educationcal video? That's like giving a restaraunt where you don't have to pay for food 1 star.

@GESTOPTKANAALDJARO 7 лет назад

my minecraft parody with 770 views has more dislikes (this video 21 my video has 23)

@BuildMineSurvive 7 лет назад

yea there's a reason for that. this channel has a team of pros.

@SmashupPvper 7 лет назад

Their finger slipped. RU-vid should really leave some space between rating buttons.

@MrAntieMatter 7 лет назад

Actually I did accidentally dislike the video, good thing I came back an hour to look at the comments, right?

@mpw4c 7 лет назад

Its like giving a free restaraunt 1 star despite the food being good. Haters gonna hate. Potatoes gonna potate

@enderking_13 Год назад

I like how slowly, we are figuring out how to bend the world around us. Instead of adapting to new conditions, we make those conditions into what we are used to, since adapting takes longer. If we keep at a pace of advancing like we currently have(and we probably won’t it should get faster) then probably in the next 10,000 years we can bend reality itself.

@susanchristner551 3 года назад

You know I've seen all of your videos and I'm kind of a nerd, I've seen Cancer, Covid-19, the most feared bacteria in the world (has a really long name) But OMG paracites make me CRY in terror. I mean I can think of a million ways the world could end but I just absolutely hate paracites. Your videos are amazing. Definitely the BEST youtuber ever, keep on educating people.

@abot5533 2 года назад

it's written parasites, not paracites

@ArcKlight 3 года назад

I am still laughing by reading that bloodlust and cuteness of a mosquito is unharmed

@futuregmchess1561 3 года назад

Cuteness lol it looks hideous

@Anonymouse0538 2 года назад

Lol same hahahahaha

@micaelgarcia8532 2 года назад

Well, their bloodlust is pretty important for the survival of the species, and cuteness may affect how they distinguish between species, so although it is funny, they are two important factors that shouldn't be messed with!

@saileshnaidu8102 2 года назад

@@micaelgarcia8532 cuteness LOL, they are HIDIOUS no matter which angle you see them with

@micaelgarcia8532 2 года назад

@@saileshnaidu8102 Well, who said their cuteness levels were positive? they just remain unchanged :P

@drcrow5767 5 лет назад

We can make every other animal extinct, but we can’t do it to the mosquitoes? COME ON HUMANS, THIS IS OUR SPECIALTY!

@colin-kun3611 5 лет назад

Ikr

@agentc7020 5 лет назад

Well but what if we create a super mosquitoe by mistake, would you want that?

@warbirdgaming8091 5 лет назад

@@agentc7020t would be easier to kill.

@oatmeal7818 5 лет назад

I think the same. Lot of ethics for mosquitos but we have killeds billion of other inocents animals

@m.j.v.4463 5 лет назад

Well, in fact we can.

@neanderthal7405 Год назад

bro please make a video on advancements in crisper genetic engineering to wipe out malaria or other diseases..

@aliabbadi5707 Год назад

Love that they even included the sleeping sickness from the flies🤣🤣🤣

@vrmpyr 6 лет назад

"Cuteness- unharmed" Oh thank god! I tought we were gonna get ugly mosquitos up in here

@chennancy8822 6 лет назад

catvee lol

@tdub6542 5 лет назад

right

@rollypolly1557 5 лет назад

Wait, they count as cute?

@andreww5 5 лет назад

but they r cute

@bakedgoldfish45 5 лет назад

catvee Mosquitoes. Check the spelling

@mishcaferraz2754 4 года назад

*mosquito bites me* Me: *searches in google* how can I bite a mosquito back

@vrv3088 4 года назад

Good idea

@PointFear 4 года назад

Mosquito does even have a mouth to bite.

@guramritpalsingh6778 4 года назад

Hahaha

@fz_de 4 года назад

This man ate a mosquito to “retrieve” his blood

@bobsempletank1222 4 года назад

**No try search in English**

@baibaimanuelz4134 2 года назад

5:52 "Omg a muto" love that😂

@Davisnacho 2 года назад

Use it. It is simple risk vs reward. The potential to save millions versus the potential of the virus adapting and edit not working is a no brained.

@raivinbarker 5 лет назад

I’m sitting here, staring at my mosquito bites, very worried.

@SDLocke 5 лет назад

Same lol

@rosietano8810 5 лет назад

Rest In Peace XD

@cooperfreeman9102 5 лет назад

Checking in a month later, did you die? XD

@JONAHcrBL4CKDR4GON 4 года назад

o3o snake? Q3Q SNNNNAAAAAKKKKKEEEEE!!!

@ghxst5595 4 года назад

Bro u ok?

@L4CHI3 7 лет назад

why is every fantastic youtube video now spoilt by the same shitty copy pasted youtube comments

@MrJonojono34 7 лет назад

why is every fantastic youtube video now spoilt by the same shitty copy pasted youtube comments

@viktor-dy9tr 7 лет назад

Because: humans

@leetri 7 лет назад

Because people need their fake internet points.

@bigearcat96 7 лет назад

Because RU-vid is dead

@Spartan0430 7 лет назад

because people won't stop giving the spammers attention

@dragongirl215 День назад

Defiantly do many test trials before releasing the super-mosquitos, like on an enclosed environment or in a quarantined part of a town or city.

@chpark3147 2 года назад

Most educational chennel ever

@bonkc7313 7 лет назад

this channel is great but I hate that he only posts once a month. these videos are fucking great then I'm craving for more of these tasty videos.

@donsancho6690 7 лет назад

Bro, this stuff is this good because of the time they take to make it. Better this than rushed, low quality half baked videos.

@leonardoangeletti948 7 лет назад

Look at the animation is all little pieces carefully stacked

@leonardoangeletti948 7 лет назад

That takes ages

@user-bl4oq7fd8d 7 лет назад

+santisan You can't bake videos, dude! They would melt :(

@Omono 7 лет назад

Making these videos is not easy. It takes time, research, animation, editing, voice acting. You can't just open premiere and click the "make video" button and be done

@c.b.7153 5 лет назад

it’s a me *_malario_*

@elias7858 5 лет назад

Facking hell good one

@doggoslayer5679 5 лет назад

Country roads itsa meeeeeeee MARIOOOOO

@silvertheelf 5 лет назад

Lol

@starly3846 5 лет назад

Best pun I’ve ever seen

@10ksubswithnovidschallenge78 5 лет назад

Lol

@abot5533 2 года назад

I live in a place where there are dengue mosquitoes (Amazonas, Peru) and it's very annoying to live every single day being afraid of getting bitten by an infected mosquitoe

@maumaiti4477 9 месяцев назад

Malaria almost took me as a when I was 9, the symptoms developed so fast in a matter of nours

@Bibky 5 лет назад

Mario says: This technology could be used for dangerous purposes, if used unethically or in a incorrect matter it could present many new problems to our ecosystem, it might turn out worse for the people we’re trying to protect. Luigi says: If he can fly he can die!

@goundz857 5 лет назад

Oh boy! It was nice of the princess to invite us to have spaghetti!

@arpithasr128 5 лет назад

thats why we have biosafety commitee to look after it..and to select which is good for all of us and nature

@bernardogouvea 4 года назад

Hello, even if used for this purpose has some danger. This has to be applied together with the education of the population, especially those living in tropical forests. For the planet's population is increasing even with fatal diseases. Without them people have to know how to use contraceptive methods. Otherwise the population will grow at a faster rate.

@bernardogouvea 4 года назад

and poorventry will raise among the world

@big_joe_8478 4 года назад

sont you mean malario lmao

@thewatchingchurch8687 7 лет назад

I want that sword.

@TexelGuy 6 лет назад

It could be a great kurzgesagt mascot. Like the master sword.

@K.azanti 6 лет назад

It's a DNA sword or something

@diebananaface 6 лет назад

it's the legendary gene slicer. You need a logic skill of 90 or over and level 50 or over to even equip it!

@kitsuko810 6 лет назад

It's not an ordinary sword it's excalibur. Only the king can wields it.

@argenteus8314 6 лет назад

It looks like Fierce Deity's sword.

@_Ducky420_ Месяц назад

As an insane godzilla fan that scene where they call a big mosquito a muto had me pointing at it with a stupid grin

@Eurofighter542 3 года назад

I remember the day when my school went on a field trip to a national health institute and we went to a place where they had mosquitoes. There were two rooms each keeping one type of mosquito and a graph between them showing the growth of mosquitoes. Anyways, we went to the second room and I saw some mosquito eggs laying straight on the water, remembering what I saw from the graph I asked one of the doctors the following: "Are these malaria mosquitoes?" "Yes." "Oh. Thanks for the terrifying news *chuckles in fear*" (we were wearing a suit with a mask and gloves so it wasn't that much of a problem)

@CT--gs1wj 7 лет назад

Mosquitoes don't kill humans, viruses do. Mosquito is insect of peace. #MosquitoLivesMatter #MosquitoesAreMisunderstood

@boomerboxer3574 7 лет назад

Exactly. This video represents the changing of mosquitoes but not actually harming them.

@johnmotherfuckincoltrane1242 7 лет назад

#Mosquitoesisareligionofpeace

@TaraZaraChara 7 лет назад

#mosquitosarefuckingannoyingandicanthaveamomentspeaceoutsidewithoutthembitingmeforcingmetogobackinside

@DavidAllen-px7gr 7 лет назад

Exactly, mosquitoes don't kill anyone, only their pathogenic payload does. The only kind of person this would hurt would be someone who can't make additional blood, which would always result in a miscarriage anyway.

@Tylernal 7 лет назад

All religons are "religons of peace." No religions are peaceful. If there are super insane followers of any religon, they will do harm. (Islam just has the most insane people)