Thank you for taking the time to make the animation and explaining the concepts. I couldn't understand the graph and didn't know how to interpret it until I watch your video. Keep up the good work!!!!
Fantastic video! I was just wondering if the net ultrafiltrate illustration at the end should actually cover even smaller highlighted area because there's a gap between the bottom line of each P_bs and pi_bs. Rather technical and not rly important (plus nothing's wrong with the calculation and equation) but just wanna make sure I get it correctly. That aside, thanks for making the video. Very succinct and helpful.
Hi, interesting observation. It's possible that it could be a little smaller in the illustration since we only approximated the calculation in the animation. Hopefully, that wasn't confusing. Thanks for the comments.
When there are proteins in a fluid, they like to keep the water for themselves and this happens in all the vessels. in this case, glomerular capillaries proteins are preventing the water from escaping towards Bowman's Capsule. AKA they "oppose" filtration.
Hi playitback8623, Good catch, you are correct, hydrostatic pressure decreases slightly as blood moves into and out of the glomerular capillary due to filtration.
Yes. In fact, this can happen when the filtration fraction increases from the typical 20% to near the maximal of 40%. This is referred to as the paradoxical effect. Does that help?
@@LanceMillerPhD Unfortunateley, I do not know about this effect. However, now I know how this is called and I will do some research. Thus, this helps me. Thank you for your answers and videos! Greetings from austria :)
You are welcome. You are not the first ask this type of question. In fact, it's a challenging topic to teach and it's often tested on the USMLE Step 1 exam. You've motived me to make a short video to explain the paradoxical effect. I'll be posting it by the end of the week. Cheers.