Gluconeogenesis Pathway: Overview, Enzymes, Co-Factors and Precursors

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Gluconeogenesis Pathway lesson: An In-Depth Overview of Required Enzymes, Co-Factors and Precursors.
Hey everyone! In this lesson you will learn about the gluconeogenesis pathway, including an in-depth overview of the pathway, where gluconeogenesis in the body, and what types of nutrient precursors can be used to synthesize glucose.
What is gluconeogenesis? Gluconeogenesis is not simply the reverse of glycolysis; gluconeogenesis requires specialized enzymes, which you will learn about in this lesson. You will also learn about how many ATP are required for the pathway, and how glycerol, lactate and various amino acids can be converted to glucose.
I am always looking for advice on how to improve my videos - any and all help would be greatly appreciated :) And as always, if you need help with any concepts, please don't hesitate to ask - I'll try my best to help you :)
JJ
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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.
Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
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Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.
I am always looking for ways to improve my lessons! Please don't hesitate to leave me feedback and comments - all of your feedback is greatly appreciated! :) And please don't hesitate to send me any messages if you need any help - I will try my best to be here to help you guys :)
Thanks for watching! If you found this video helpful, please like and subscribe!
JJ

Опубликовано:

5 окт 2024

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Комментарии : 82

@kileyross998 2 года назад

very clear explanation but I have no idea how I am going to memorize all of this

@marcus00077 5 лет назад

I have no idea what I would do without your channel! Thank you !!

@917hshzuan2 2 года назад

Sleep?

@M1c2h3 3 года назад

Great! Not too detailed to lose the overview but detailed enough to understand more than just the general pathway

@abdallahelsabbagh7403 4 года назад

Really well organized and thorough explanation- thank you so much

@alvarorietmann7546 5 лет назад

Thank you!!! I enjoyed your video and explanation a lot more than other more "popular" videos

@hannamiller4466 4 года назад

ALL of your videos are life changing and excellent. THANK YOU

@ashle2714 4 года назад

This was very well explained but I really wish you would just have one long commercial in the middle instead of all the mini ones. Very distracting

@ateffayed1 Год назад

Simple and made easy. Thank you for your hard work :)

@Thegoodchanelsonly Год назад

The summarization cascades are very clear and good , clearer than references cascades ….

@missceeceeoh Год назад

I LOVE YOUR VIDEOS ABOUT BIOCHEMISTRY !!! THANK YOU !! REALLY HELPED ME A LOOOT

@syafinazsharif7351 3 года назад

this is soooo helpful, very clear explanation ! thank you

@bilgesultan2306 4 года назад

Thank you so much, everything is really clear 🌺

@harman_sidhu95 2 года назад

😳😳😳😳 what r u saying

@esraakhamees986 3 года назад

This is more than perfect

@banmahmood9339 4 года назад

Thank you so much, you did a great job saving my life 😂❤️

@yogayantra 4 года назад

I love your videos on chemistry. thank you so much

@arkajyotibanerjee8308 3 года назад

Very well explained. Thank you.

@SirBroni 5 лет назад

It very thoughtful, I actually understood the concept

@heyheidi8 6 лет назад

I think it might be gluconeogenesis requires 4 ATP (2 from pyruvate to PEP, 2 from 3 p glycerate - 1,3 bisp glycerate 6 p) and 2 GTP

@Zetsuke4 5 лет назад

By far the best video on this topic sooo good

@roaamaged4311 11 месяцев назад

it was so helpful thank you for your hard work

@xeebot 5 лет назад

Very clear explanation. thank you

@jgbdickcleland 5 лет назад

Hi there. Could you link the video going deeper into the mechanisms of amino acid usage please? You named it right at the end. Thanks for your efforts with these. J

@abdullahbrock952 3 года назад

i guess Im randomly asking but does someone know of a way to get back into an Instagram account?? I stupidly lost the password. I would appreciate any assistance you can offer me

@greysonira4536 3 года назад

@Abdullah Brock instablaster =)

@abdullahbrock952 3 года назад

@Greyson Ira Thanks for your reply. I found the site through google and I'm waiting for the hacking stuff atm. Looks like it's gonna take a while so I will get back to you later with my results.

@abdullahbrock952 3 года назад

@Greyson Ira It worked and I now got access to my account again. I am so happy:D Thanks so much you saved my ass :D

@greysonira4536 3 года назад

@Abdullah Brock No problem :D

@ferinasteffi4978 2 года назад

Very helpful, thanks

@niloofarrabiei5257 4 года назад

Amazing, thank you so much, I really enjoyed it, this video should get millions of likes!!!

@jjmedicine 4 года назад

Thank you so much!! Glad you liked it :)

@wasgames3541 4 месяца назад

Amazing 🤩 presentation

@olinekihlman5435 2 года назад

Verry good video, easy to understand and remember. But according to my biochem book does Glucose go through T2 and Pi through T3

@bitaelisha1891 Год назад

Good explanation..sir, But assist me understand how Propionyl CoA incorporated into the gluconeogenesis pathway?

@dinuandish8301 3 года назад

thank you sir.

@Xiaoyu100 4 года назад

Really helpful!

@yasirmohammedali 3 года назад

Hi ... Thanks for your videos

@juststudies8341 3 года назад

This was very helpful! Thank you

@forumjoshi6279 5 лет назад

cleared my concepts thank you

@yogayantra 5 лет назад

thank you so much. I love all your videos

@anaherrera4805 Год назад

Great video !

@fawwazali8169 3 года назад

Amazing video altogether but, could you explain how does glyceraldehyde 3 phosphate (3 carbon) get converted to fructose 1,6 biphosphate?

@Tchotch_ke 2 года назад

By the enzyme triose phosphate isomerase. As these reactions are reversible the enzymes are same with glycolysis (but in reverse manner) except the three reactions where Hexokinase, phosphofructokinase 1 and pyruvate kinase are involved.

@sam-lj9lz 9 месяцев назад

@@Tchotch_ke this is old but u actually need aldolase to convert GAP into fructose 1,6-bisphosphate. the enzyme u mentioned is the one we use to turn DHAP into GAP (both in glycolysis and gluconeogenesis)

@emastrovito 2 года назад

If I got it right it looks like glycerol has a shorter/easier path to glucose than amino acids (i.e. proteins) and lactate, does that mean that the body will favor glycerol (i.e. fat) during fasting to supply the body with glucose?

@ketoonkratom 2 года назад

Love One Another God Bless Everyone

@markaguilera493 8 месяцев назад

So which of amino acids and glycerol are the greater precursor of glucose?

@yogayantra 6 лет назад

great video, and so clear. thank you

@ozumeceozcan6231 3 года назад

But i have heard everywhere else that the first step of glycolysis is irreversible??

@alevelsdemystified3410 3 года назад

so helpful 💜

@abigailthylda5842 5 лет назад

thank you!!

@swen6797 7 месяцев назад

Brain can switch to burn fat only when leptin signal gets to it, otherwise only stuck burning glucose. Almost all brains have stuck the body in glucose burning mode. This is a crux for the proper understanding of fasting and starvation.

@IsratjahanLiza-h7k 9 месяцев назад

Awesome 😍😍😍

@mohanjr 7 лет назад

Lypolysis , beta oxidation alpha ...... thnks 😊

@kaustubhrege969 3 года назад

Thanks

@manicpixiedreamgirl7930 6 лет назад

You're awesome! Thanks!

@michaelrowland-us3he 5 месяцев назад

Will people doing the keto diet only get glucose from gluconeogenesis

@mohamedalipasha7753 4 года назад

If you can help me please tell me about the two reactions that convert pyruvate back into PEP quickly please

@pigeonlove 4 года назад

Why would you not Google that?

@Medic-ulous 3 года назад

i LOVE ur vids

@davecristianconejos7524 3 года назад

Is there any difference between glucogenesis and gluconeogenesis???

@tul_ipa520 3 года назад

No ,the process is called gluconeogenesis not glucogenesis Gluco---glucose Neo------new Genesis---formation Hope its useful!

@lauralaura5042 4 года назад

Why we have more NADH in the mythocondria (5:21)?

@hamiddarabi5506 4 года назад

because crebs cycle takes place there

@nehartandcraft День назад

Can be use this msc. Zoology. Semster. 1. This gluconeogenesis according to 2024. -2025

@timetothrive1637 6 лет назад

What percentage of the brain can run completely off beta hydroxybutyrate in place of glucose?

@user-po6ln2gd2l 5 лет назад

aprox. 20% I believe

@ProfFeinman 3 года назад

It can be slightly greater than 50 %

@btudrus Год назад

It depends on the state. There seems to be some adaptation going on with prolonged fasting (>4~7 days).

@btudrus Год назад

0:51 "Brain requires Glucose" -- this is not accurate. Brain requires glucose TO A DEGREE. But the brain is completely happy with a mix of ketone bodies and a some amount of glucose. The brain can even use other fuels like lactate very effectively as an additional fuel sources. Which means during fasting the brain is more than happy with about 2~3 mmol/l of blood sugar if the BHB levels are steadily above about 5~6 mmol/l.