It seems that the information available is weak. Looking at the women's age but also lifestyle factors such as obesity, smoking, alcohol consumption, diet and cardiovascular exercise. The only certain information appears to be women with worse menopausal symptoms and earlier menopause onset have higher risk of stroke. It seems if women have severe menopausal symptoms they should be put on hormone therapy without question. If men went through menopause I believe we would know so much more.
Absolutely, thank you for commenting this mostly outdated info on oral synthetic HRT. Anyone interested in modern evidence-based info should go to the RU-vid channel of British menopause specialist of the brilliant Dr. Louise Newson... 🙏💪
Modern HRT does NOT use the old synthetic medroxyprogesterone anymore which must indeed be associated with higher risk of stroke & CVD... Instead BODYIDENTICAL MICRONIZED progesterone is used. In the estradial-only arm of the WHI study, women had better outcomes for all risks. So don't blame any increased risks on estradiol. By the way, most of the studies cited here were done with the old horse-urine-based ORAL synthetic estradiol which gets metabolized in the liver and indeed increases the risks of clotting ... Good that you at least mentioned much better risk-benefit-outcomes for transdermal! Please, finally start researching the MODERN types of HRT instead of spreading old, outdated info scaring women away from the only long-term intervention to deal with symptoms and diseases associated with hormone deficiency (=menopause)...
