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How Adrenaline and Acetylcholine Affect Heart Rate

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In this episode, I discuss the effect of Adrenaline and Acetylcholine on heart rate. Adrenaline speeds it up and Acetylcholine slows it down. They both have their effect by modifying the conductance for ions such as Sodium, Potassium and Calcium across the membrane of the cells of the SA node. Watch the video to find out how :)
➟ Video Chapters
00:00 Intro
00:58 Release of adrenaline from the body
01:18 Effect of adrenaline release in pacemaker cell conductance
01:46 Action potential graph with increased adrenaline release
02:33 Release of acetylcholine from the body
02:46 Effect of acetylcholine release in pacemaker cell conductance
03:07 The action potential graph with increased acetylcholine release
04:03 Summary
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Опубликовано:

17 авг 2024

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Комментарии : 43

@SamGuthrie1977 12 лет назад

Thanks! Great video -- this is exactly what I was looking for concerning Acetylcholine's effects on heart rate.

@InteractiveBiology 13 лет назад

@petercourt Yes, that's correct. That's what I said in the video. When it reaches the threshold, Calcium channels open, resulting in Calcium rushing in. Sodium is involved in the pacemaker potential primarily and how the membrane depolarizes to reach the threshold, but the overwhelming effect is due to Calcium causing the action potential. Hope that answers your questions!

@janedee3271 10 лет назад

When I read about this I was so confused. Thank you heaps much for making it not just simple but easy to remember!

@InteractiveBiology 13 лет назад

@petercourt You're Welcome!

@billyshears678 8 лет назад

Just an fyi that, physiologically speaking, acetylcholinergic agents actually increase heart rate when administered. Ach's effect on the SA node is weaker than the vasodilatory effects systemically (which cause a drop in blood pressure) and in response there is a reflex tachycardia (a compensatory increase in heart rate).

@mattwilson7443 4 года назад

The explanation in the video still confuses me. Doesn't potassium want to stay around -92 mV, so if ACh causes potassium to leave the cell more quickly wouldn't the cell depolarize more quickly as well as?

@mhealthlete1322 8 лет назад

I love these interactive biology videos they are sooooooo simplified and helpful!!!

@jewelonvacation7962 7 лет назад

I don't know why.. I'm actually enjoying it :D Thank you so much!

@GGCMGC 8 лет назад

I love and I am grateful for every video here. It helps a lot. What about the plateau in the pacemaker?

@InteractiveBiology 13 лет назад

@johny2481 Thank you sir. Glad to know you are finding value in the content. Stay tuned for many more videos :)

@InteractiveBiology 12 лет назад

@KurikuShot Glad this helped a lot :) We have more Biology videos in our website just in case you need more help. Stay tuned!

@AmandaFlopp Год назад

The video was so helpful. Thanks

@InteractiveBiology Год назад

You're very much welcome, Amanda. I'm glad you found the video helpful. Make sure to subscribe and stay tuned for more.

@dr.shamsridha3088 8 лет назад

that was so nice and easy !! it help me for my study in the pharmacology thank you

@Alexsh2010 11 лет назад

This was really really helpful! Thanks!

@VinodSharma-vf5dd 3 года назад

Q. Acetylcholine effect on heart rate and Blood pressure A. Increase B. Decrease

@wezzard759 2 года назад

it’s not specific as you didn’t view by which cns the epinephrine was released and to which receptor did it bound ?

@romeolhk1008 9 лет назад

This is precious!

@abrara321 12 лет назад

gd job my teacher . i have a question , you said that adrenaline released when we get scary, what about acetylcholine what causes it to be released ? ?

@user-pi1xh1ol1t 6 лет назад

Thank you . Perfect explanation

@marcelamartinez8103 11 лет назад

I watch at least one of your videos randomly before I go to sleep,.

@InteractiveBiology 13 лет назад

@Livinglifehigh Yeah and that was a mistake. Maybe I need to be burning everything in my videos from now on. Keeps things interesting - LOL.

@abdulfattah8616 4 года назад

thank you sir, was very helpful

@SasidharMittapalli 11 лет назад

Thank you that was just perfect explanation i was looking for. You din't mention when acetlycholine will be released?

@jdgatlin8813 2 года назад

Is it possible that high acetylcholine levels is the reason for my low back getting crazy tight. I take pre workout. So just wondering

@Sonamyfan92 9 лет назад

This was helpful when trying to study for my bio test! C:

@petercourt 13 лет назад

Isn't the upward deflection of an action potential in the SAN a result of the inward movement of calcium ions, rather than sodium ions?

@Wolf3fd 6 лет назад

Well the thing I struggle with is that if you use an overdose of Acetylcholine, it will increase the production of adrenalin due to its effect on ggl. neurons via Nicotine-receptors.... so the final effect will be what? It will cause tachycardia. Or?

@richaisdbest 11 лет назад

Hi...i have a question...dosent hyperpolarisation occur beyond the RMP ?? In the depiction the hyperpolarisation was not shown or i am lacking some concept here..please correct me if i am wrong...on the whole a very nice video!